Bicocca Open Archive

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LONGHESE, MARIA PIA
 Distribuzione geografica
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Continente #
NA - Nord America 12.225
EU - Europa 7.263
AS - Asia 4.965
SA - Sud America 636
AF - Africa 78
Continente sconosciuto - Info sul continente non disponibili 7
OC - Oceania 4
Totale 25.178
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Nazione #
US - Stati Uniti d'America 11.961
IT - Italia 2.064
SG - Singapore 1.621
CN - Cina 1.438
DE - Germania 989
RU - Federazione Russa 774
SE - Svezia 737
HK - Hong Kong 680
PL - Polonia 634
VN - Vietnam 568
BR - Brasile 519
IE - Irlanda 391
GB - Regno Unito 367
FR - Francia 341
UA - Ucraina 338
CA - Canada 196
IN - India 182
AT - Austria 147
FI - Finlandia 142
NL - Olanda 109
DK - Danimarca 99
KR - Corea 91
TR - Turchia 89
ID - Indonesia 84
BD - Bangladesh 45
AR - Argentina 44
MX - Messico 44
ZA - Sudafrica 43
BE - Belgio 40
JP - Giappone 37
ES - Italia 26
EC - Ecuador 25
IQ - Iraq 21
SA - Arabia Saudita 16
PK - Pakistan 14
CH - Svizzera 12
VE - Venezuela 12
UZ - Uzbekistan 10
CO - Colombia 9
AE - Emirati Arabi Uniti 8
MA - Marocco 8
EG - Egitto 7
GR - Grecia 7
IL - Israele 7
KZ - Kazakistan 7
LT - Lituania 7
PE - Perù 7
PY - Paraguay 7
UY - Uruguay 7
AZ - Azerbaigian 6
CZ - Repubblica Ceca 6
EU - Europa 6
IR - Iran 6
OM - Oman 6
PH - Filippine 6
BG - Bulgaria 5
CL - Cile 5
DO - Repubblica Dominicana 5
KE - Kenya 5
RS - Serbia 5
JM - Giamaica 4
PT - Portogallo 4
SC - Seychelles 4
TT - Trinidad e Tobago 4
AU - Australia 3
JO - Giordania 3
KG - Kirghizistan 3
MD - Moldavia 3
MY - Malesia 3
NP - Nepal 3
RO - Romania 3
BA - Bosnia-Erzegovina 2
CR - Costa Rica 2
DZ - Algeria 2
ET - Etiopia 2
GE - Georgia 2
HN - Honduras 2
HR - Croazia 2
MU - Mauritius 2
NO - Norvegia 2
PA - Panama 2
PS - Palestinian Territory 2
SK - Slovacchia (Repubblica Slovacca) 2
TN - Tunisia 2
TW - Taiwan 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AL - Albania 1
BB - Barbados 1
BN - Brunei Darussalam 1
BS - Bahamas 1
CY - Cipro 1
DM - Dominica 1
GA - Gabon 1
GD - Grenada 1
GT - Guatemala 1
GY - Guiana 1
HU - Ungheria 1
IS - Islanda 1
KH - Cambogia 1
KW - Kuwait 1
Totale 25.172
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Città #
Ann Arbor 2.426
Ashburn 1.271
Singapore 975
Fairfield 932
Woodbridge 815
Milan 748
Hong Kong 676
Houston 662
Chandler 659
Frankfurt am Main 649
Wilmington 605
Kraków 594
Dublin 378
Seattle 372
Jacksonville 361
New York 290
Cambridge 278
Dearborn 258
Santa Clara 230
Beijing 226
Los Angeles 204
Hefei 182
Princeton 164
Ho Chi Minh City 143
Dallas 140
Vienna 137
Dong Ket 128
Nanjing 117
Moscow 109
Shanghai 95
Altamura 92
Seoul 89
Hanoi 82
Lawrence 81
Buffalo 70
Jakarta 69
Guangzhou 66
San Diego 64
Council Bluffs 62
Chicago 61
Rome 58
Lachine 55
Fremont 54
Munich 53
São Paulo 52
Helsinki 51
The Dalles 50
Nanchang 48
Boardman 45
Brussels 39
London 39
Ottawa 38
Toronto 36
Andover 29
Hebei 29
Montreal 29
Johannesburg 27
Tokyo 27
Atlanta 26
Botticino 26
Brooklyn 26
Huizen 26
Jinan 26
Warsaw 26
Changsha 24
Stockholm 24
Denver 23
Shenyang 23
Tianjin 23
Kunming 22
Seveso 22
Zhengzhou 21
Brescia 19
Capralba 19
Da Nang 19
Falls Church 19
Poplar 19
Tampa 19
Turku 19
Mexico City 18
New Delhi 18
Nuremberg 18
Orem 18
Philadelphia 18
Salt Lake City 18
Chennai 17
Cuggiono 17
Haiphong 16
Sacramento 16
Sesto San Giovanni 16
Taizhou 16
Cinisello Balsamo 15
Edmonton 15
Jiaxing 15
Brasília 14
Desio 14
Düsseldorf 14
Auburn Hills 13
Manchester 13
Montpellier 13
Totale 17.122
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Nome #
Structure–function relationships of the Mre11 protein in the control of DNA end bridging and processing 526
Sae2 Function at DNA Double-Strand Breaks Is Bypassed by Dampening Tel1 or Rad53 Activity 505
DNA binding modes influence Rap1 activity in the regulation of telomere length and MRX functions at DNA ends 493
Uncoupling Sae2 functions in downregulation of Tel1 and Rad53 signaling activities 482
The MRX complex regulates Exo1 resection activity by altering DNA end structure 475
The ATP-bound conformation of the Mre11-Rad50 complex is essential for Tel1/ATM activation 459
Tel1/ATM Signaling to the Checkpoint Contributes to Replicative Senescence in the Absence of Telomerase 452
Processing of DNA double-strand breaks by the MRX complex in a chromatin context 431
Structurally distinct Mre11 domains mediate MRX functions in resection, end-tethering and DNA damage resistance 423
Tel1 and Rif2 Regulate MRX Functions in End-Tethering and Repair of DNA Double-Strand Breaks 402
Rad9/53BP1 protects stalled replication forks from degradation in Mec1/ATR-defective cells 401
Tel1/ATM prevents degradation of replication forks that reverse after topoisomerase poisoning 398
Exo1 cooperates with Tel1/ATM in promoting recombination events at DNA replication forks 396
Functions and regulation of the MRX complex at DNA double-strand breaks 373
Regulation of telomere metabolism by the RNA processing protein Xrn1 373
Escape of Sgs1 from Rad9 inhibition reduces the requirement for Sae2 and functional MRX in DNA end resection 361
Local unwinding of double-strand DNA ends by the MRX complex promotes Exo1 processing activity 361
Resection of a DNA Double-Strand Break by Alkaline Gel Electrophoresis and Southern Blotting 358
Coupling end resection with the checkpoint response at DNA double-strand breaks 349
The regulation of the DNA damage response at telomeres: Focus on kinases 347
Processing of DNA ends in the maintenance of genome stability 338
Sensing R-Loop-Associated DNA Damage to Safeguard Genome Stability 337
DNA double-strand breaks in meiosis: Checking their formation, processing and repair 328
The 9-1-1 Complex Controls Mre11 Nuclease and Checkpoint Activation during Short-Range Resection of DNA Double-Strand Breaks 319
Distinct Cdk1 requirements during single-strand annealing, noncrossover and crossover recombination 314
G(1)/S and G(2)/M cyclin-dependent kinase activities commit cells to death in the absence of the S-phase checkpoint. 311
The RNA binding protein Npl3 promotes resection of DNA double-strand breaks by regulating the levels of Exo1 307
Tbf1 and Vid22 promote resection and non-homologous end joining of DNA double-strand break ends 301
Functional and structural insights into the MRX/MRN complex, a key player in recognition and repair of DNA double-strand breaks 300
A balance between Tel1 and Rif2 activities regulates nucleolytic processing and elongation at telomeres 298
How do cells sense DNA lesions? 298
Resection is responsible for loss of transcription around a double-strand break in Saccharomyces cerevisiae 297
Mechanisms and regulation of DNA end resection 290
Dpb4 promotes resection of DNA double-strand breaks and checkpoint activation by acting in two different protein complexes 290
The MRX complex plays multiple functions in resection of Yku- and Rif2-protected DNA ends 288
A Tel1/MRX-dependent checkpoint inhibits the metaphase-to-anaphase transition after UV irradiation in the absence of Mec1 286
The Saccharomyces cerevisiae Sae2 protein promotes resection and bridging of double strand break ends 286
Interplays between ATM/Tel1 and ATR/Mec1 in sensing and signaling DNA double-strand breaks 286
RNA-processing proteins regulate Mec1/ATR activation by promoting generation of RPA-coated ssDNA 278
Rif2 interaction with Rad50 counteracts Tel1 functions in checkpoint signalling and DNA tethering by releasing Tel1 from MRX binding 276
Rif1 supports the function of the CST complex in yeast telomere capping 274
Processing of meiotic DNA double strand breaks requires cyclin-dependent kinase and multiple nucleases 270
Hyperactivation of the yeast DNA damage checkpoint by TEL1 and DDC2 overexpression 268
Saccharomyces cerevisiae Rif1 cooperates with MRX-Sae2 in promoting DNA-end resection 268
The cellular response to chromosome breakage 267
Telomeres and DNA damage checkpoints 265
The S-phase checkpoint and its regulation in Saccharomyces cerevisiae 263
Multiple pathways regulate 3’ overhang generation at S. cerevisiae telomeres 260
Characterization of mec1 kinase-deficient mutants and of new hypomorphic mec1 alleles impairing subsets of the DNA damage response pathway 256
The Yku70-Yku80 complex contributes to regulate double-strand break processing and checkpoint activation during the cell cycle 256
Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation. 248
functional and physical interactions between yeast 14-3-3 proteins, acetyltransferases, and deacetylases in response to DNA replication perturbations 242
Surveillance mechanisms monitoring chromosome breaks during mitosis and meiosis 241
Mec1/ATR regulates the generation of single-stranded DNA that attenuates Tel1/ATM signaling at DNA ends 241
The chromatin remodeler Chd1 supports MRX and Exo1 functions in resection of DNA double-strand breaks 241
Role of the Saccharomyces cerevisiae Rad53 checkpoint kinase in signaling double-strand breaks during the meiotic cell cycle. 238
Shelterin-like proteins and Yku inhibit nucleolytic processing of S. cerevisiae telomeres 237
The General Regulatory Factor Tbf1 and its interacting protein Vid22 promote repair of DNA double-strand breaks 237
PP2A Controls Genome Integrity by Integrating Nutrient-Sensing and Metabolic Pathways with the DNA Damage Response 237
Physical and functional interactions between nucleotide excision repair and DNA damage checkpoint 232
The checkpoint protein Ddc2, functionally related to S. pombe Rad26, interacts with Mec1 and is regulated by Mec1-dependent phosphorylation in budding yeast. 232
Sae2 and Rif2 regulate MRX endonuclease activity at DNA double-strand breaks in opposite manners 231
The Ku complex promotes DNA end-bridging and this function is antagonized by Tel1/ATM kinase 230
Dual role for Saccharomyces cerevisiae Tel1 in the checkpoint response to double-strand breaks. 230
RPA regulates telomerase action by providing Est1p access to chromosome ends 229
Budding yeast Sae2 is an in vivo target of the Mec1 and Tel1 checkpoint kinases during meiosis 228
Interplay between Sae2 and Rif2 in the regulation of Mre11-Rad50 activities at DNA ends 228
The Saccharomyces cerevisiae 14-3-3 proteins are required for the G 1/S transition, actin cytoskeleton organization and cell wall integrity 226
The Saccharomyces cerevisiae Sae2 protein negatively regulates DNA damage checkpoint signalling 225
The PP2A phosphatase counteracts the function of the 9-1-1 axis in checkpoint activation 224
Functional and molecular insights into the role of Sae2 C-terminus in the activation of MRX endonuclease 222
The functions of budding yeast Sae2 in the DNA damage response require Mec1- and Tel1-dependent phosphorylation 218
The set1Δ mutation unveils a novel signaling pathway relayed by the Rad53-dependent hyperphosphorylation of replication protein A that leads to transcriptional activation of repair genes 215
Sudden telomere lengthening triggers a Rad53-dependent checkpoint in Saccharomyces cerevisiae 214
To Fix or Not to Fix: Maintenance of Chromosome Ends Versus Repair of DNA Double-Strand Breaks 214
The DNA damage checkpoint: A tale from budding yeast 208
A central role for DNA replication forks in checkpoint activation and response 208
MRX-dependent DNA damage response to short telomeres 204
Dephosphorylation of γH2A by Gcl7/Protein Phosphatase 1 promotes recovery from inhibition of DNA replication 203
Irreparable telomeric DNA damage and persistent DDR signalling as a shared causative mechanism of cellular senescence and ageing 201
DNA damage response at functional and dysfunctional telomeres 198
Dominant TEL1-hy mutations compensate for Mec1 lack of functions in the DNA damage response 197
Functions of Saccharomyces cerevisiae 14-3-3 proteins in response to DNA damage and to DNA replication stress 192
The Mec1p and Tel1p checkpoint kinases allow humanized yeast to tolerate chronic telomere dysfunctions by suppressing telomere fusions 192
Telomere-end processing: mechanisms and regulation 184
The role of shelterin in maintaining telomere integrity 181
Multi-pathway blood biomarkers to target and monitor multidimensional prevention of cognitive and functional decline (nested in the IN-TeMPO study framed within the world-wide FINGERS network) 170
Regulation of the DNA damage response by cyclin-dependent kinases 164
Proteasome-mediated degradation of long-range nucleases negatively regulates resection of DNA double-strand breaks 160
Checkpoint proteins influence telomeric silencing and length maintenance in budding yeast. 159
The Rad53CHK1/CHK2-Spt21NPAT and Tel1ATM axes couple glucose tolerance to histone dosage and subtelomeric silencing 149
Checkpoint activation and recovery: regulation of the 9–1–1 axis by the PP2A phosphatase 130
Stn1 supports Mec1 function in protecting stalled replication forks from degradation 82
Totale 25.982
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Categoria #
all - tutte 76.093
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 76.093
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.873 0 0 0 0 0 278 244 245 239 344 168 355
2021/20221.907 167 214 296 200 125 147 107 95 64 88 179 225
2022/20232.737 281 782 283 295 181 367 32 147 196 36 102 35
2023/20241.740 61 71 46 124 190 419 299 194 112 26 41 157
2024/20253.724 185 327 245 173 265 169 261 134 269 769 339 588
2025/20265.284 1.053 662 692 1.208 1.206 463 0 0 0 0 0 0
Totale 25.982