LONGHESE, MARIA PIA
 Distribuzione geografica
Continente #
NA - Nord America 10.344
EU - Europa 6.811
AS - Asia 2.482
SA - Sud America 107
AF - Africa 21
Continente sconosciuto - Info sul continente non disponibili 7
OC - Oceania 4
Totale 19.776
Nazione #
US - Stati Uniti d'America 10.185
IT - Italia 1.881
DE - Germania 956
RU - Federazione Russa 760
SE - Svezia 718
CN - Cina 689
HK - Hong Kong 633
SG - Singapore 633
PL - Polonia 606
IE - Irlanda 387
UA - Ucraina 330
FR - Francia 329
GB - Regno Unito 292
VN - Vietnam 175
CA - Canada 152
AT - Austria 142
FI - Finlandia 127
IN - India 109
DK - Danimarca 99
BR - Brasile 89
NL - Olanda 88
TR - Turchia 75
ID - Indonesia 68
KR - Corea 42
BE - Belgio 40
ES - Italia 11
CH - Svizzera 10
JP - Giappone 10
ZA - Sudafrica 10
GR - Grecia 7
AR - Argentina 6
EU - Europa 6
MX - Messico 6
PK - Pakistan 6
UZ - Uzbekistan 6
BD - Bangladesh 5
CZ - Repubblica Ceca 5
IR - Iran 5
AZ - Azerbaigian 4
MA - Marocco 4
PT - Portogallo 4
RS - Serbia 4
SC - Seychelles 4
AU - Australia 3
BG - Bulgaria 3
EC - Ecuador 3
IL - Israele 3
KZ - Kazakistan 3
PE - Perù 3
PH - Filippine 3
CO - Colombia 2
IQ - Iraq 2
LT - Lituania 2
MU - Mauritius 2
MY - Malesia 2
NO - Norvegia 2
PY - Paraguay 2
TW - Taiwan 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AE - Emirati Arabi Uniti 1
CL - Cile 1
CY - Cipro 1
EG - Egitto 1
GE - Georgia 1
HR - Croazia 1
HU - Ungheria 1
IS - Islanda 1
JO - Giordania 1
KW - Kuwait 1
LV - Lettonia 1
MD - Moldavia 1
MK - Macedonia 1
NZ - Nuova Zelanda 1
PA - Panama 1
PS - Palestinian Territory 1
RO - Romania 1
SK - Slovacchia (Repubblica Slovacca) 1
TH - Thailandia 1
VE - Venezuela 1
Totale 19.776
Città #
Ann Arbor 2.426
Fairfield 931
Woodbridge 815
Ashburn 703
Milan 688
Chandler 659
Houston 649
Frankfurt am Main 642
Hong Kong 630
Wilmington 603
Kraków 594
Singapore 448
Dublin 375
Seattle 366
Jacksonville 361
Cambridge 278
Dearborn 258
New York 213
Santa Clara 209
Princeton 164
Vienna 135
Dong Ket 128
Nanjing 117
Moscow 108
Altamura 92
Shanghai 90
Lawrence 81
Beijing 65
Jakarta 65
San Diego 64
Council Bluffs 61
Guangzhou 55
Lachine 55
Fremont 54
Helsinki 50
Nanchang 48
Rome 48
Boardman 45
Los Angeles 42
Seoul 40
Brussels 39
Ottawa 37
Munich 31
Toronto 30
Andover 29
Hebei 29
Hefei 29
Botticino 26
Huizen 26
Jinan 26
London 23
Kunming 22
Shenyang 21
Capralba 19
Falls Church 19
Zhengzhou 19
Seveso 18
Changsha 17
Chicago 17
Cuggiono 17
Tianjin 17
Brescia 16
Nuremberg 16
Philadelphia 16
Sacramento 16
Cinisello Balsamo 15
Edmonton 15
Jiaxing 15
Dallas 14
Düsseldorf 14
Taizhou 14
Auburn Hills 13
Montpellier 13
Mountain View 13
Novate Milanese 13
Sesto San Giovanni 13
Vedano al Lambro 13
Bonndorf 12
Kiev 12
Ningbo 12
Norwalk 11
Turku 11
Pavia 10
Rossiglione 10
Seregno 10
São Paulo 10
Como 9
New Delhi 9
Romola 9
Stockholm 9
Bologna 8
Grafing 8
Hangzhou 8
Leawood 8
Santa Cruz 8
Tappahannock 8
Torino 8
Verona 8
Changchun 7
Citta Sant'angelo 7
Totale 14.407
Nome #
Structure–function relationships of the Mre11 protein in the control of DNA end bridging and processing 468
Sae2 Function at DNA Double-Strand Breaks Is Bypassed by Dampening Tel1 or Rad53 Activity 446
DNA binding modes influence Rap1 activity in the regulation of telomere length and MRX functions at DNA ends 437
Uncoupling Sae2 functions in downregulation of Tel1 and Rad53 signaling activities 427
The MRX complex regulates Exo1 resection activity by altering DNA end structure 411
Tel1/ATM Signaling to the Checkpoint Contributes to Replicative Senescence in the Absence of Telomerase 395
The ATP-bound conformation of the Mre11-Rad50 complex is essential for Tel1/ATM activation 393
Processing of DNA double-strand breaks by the MRX complex in a chromatin context 371
Structurally distinct Mre11 domains mediate MRX functions in resection, end-tethering and DNA damage resistance 361
Tel1/ATM prevents degradation of replication forks that reverse after topoisomerase poisoning 345
Tel1 and Rif2 Regulate MRX Functions in End-Tethering and Repair of DNA Double-Strand Breaks 328
Rad9/53BP1 protects stalled replication forks from degradation in Mec1/ATR-defective cells 328
Regulation of telomere metabolism by the RNA processing protein Xrn1 307
Resection of a DNA Double-Strand Break by Alkaline Gel Electrophoresis and Southern Blotting 303
Local unwinding of double-strand DNA ends by the MRX complex promotes Exo1 processing activity 301
Functions and regulation of the MRX complex at DNA double-strand breaks 292
Escape of Sgs1 from Rad9 inhibition reduces the requirement for Sae2 and functional MRX in DNA end resection 292
Coupling end resection with the checkpoint response at DNA double-strand breaks 288
Processing of DNA ends in the maintenance of genome stability 285
DNA double-strand breaks in meiosis: Checking their formation, processing and repair 270
Sensing R-Loop-Associated DNA Damage to Safeguard Genome Stability 270
Distinct Cdk1 requirements during single-strand annealing, noncrossover and crossover recombination 265
The RNA binding protein Npl3 promotes resection of DNA double-strand breaks by regulating the levels of Exo1 258
Tbf1 and Vid22 promote resection and non-homologous end joining of DNA double-strand break ends. 256
The regulation of the DNA damage response at telomeres: Focus on kinases 256
The Saccharomyces cerevisiae Sae2 protein promotes resection and bridging of double strand break ends 248
The 9-1-1 Complex Controls Mre11 Nuclease and Checkpoint Activation during Short-Range Resection of DNA Double-Strand Breaks 248
A balance between Tel1 and Rif2 activities regulates nucleolytic processing and elongation at telomeres 243
G(1)/S and G(2)/M cyclin-dependent kinase activities commit cells to death in the absence of the S-phase checkpoint. 240
A Tel1/MRX-dependent checkpoint inhibits the metaphase-to-anaphase transition after UV irradiation in the absence of Mec1 239
Resection is responsible for loss of transcription around a double-strand break in Saccharomyces cerevisiae 238
Interplays between ATM/Tel1 and ATR/Mec1 in sensing and signaling DNA double-strand breaks 235
The MRX complex plays multiple functions in resection of Yku- and Rif2-protected DNA ends 234
Mechanisms and regulation of DNA end resection 233
Telomeres and DNA damage checkpoints 231
Processing of meiotic DNA double strand breaks requires cyclin-dependent kinase and multiple nucleases 226
Rif1 supports the function of the CST complex in yeast telomere capping 226
RNA-processing proteins regulate Mec1/ATR activation by promoting generation of RPA-coated ssDNA 226
The cellular response to chromosome breakage 224
Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation. 224
Hyperactivation of the yeast DNA damage checkpoint by TEL1 and DDC2 overexpression 222
How do cells sense DNA lesions? 222
The Yku70-Yku80 complex contributes to regulate double-strand break processing and checkpoint activation during the cell cycle 221
Functional and structural insights into the MRX/MRN complex, a key player in recognition and repair of DNA double-strand breaks 218
Dpb4 promotes resection of DNA double-strand breaks and checkpoint activation by acting in two different protein complexes 218
Characterization of mec1 kinase-deficient mutants and of new hypomorphic mec1 alleles impairing subsets of the DNA damage response pathway 216
Multiple pathways regulate 3’ overhang generation at S. cerevisiae telomeres 216
Saccharomyces cerevisiae Rif1 cooperates with MRX-Sae2 in promoting DNA-end resection 213
The S-phase checkpoint and its regulation in Saccharomyces cerevisiae 204
functional and physical interactions between yeast 14-3-3 proteins, acetyltransferases, and deacetylases in response to DNA replication perturbations 203
Mec1/ATR regulates the generation of single-stranded DNA that attenuates Tel1/ATM signaling at DNA ends 203
Physical and functional interactions between nucleotide excision repair and DNA damage checkpoint 201
Surveillance mechanisms monitoring chromosome breaks during mitosis and meiosis 199
RPA regulates telomerase action by providing Est1p access to chromosome ends 196
Budding yeast Sae2 is an in vivo target of the Mec1 and Tel1 checkpoint kinases during meiosis 195
The General Regulatory Factor Tbf1 and its interacting protein Vid22 promote repair of DNA double-strand breaks 195
Dual role for Saccharomyces cerevisiae Tel1 in the checkpoint response to double-strand breaks. 194
The functions of budding yeast Sae2 in the DNA damage response require Mec1- and Tel1-dependent phosphorylation 189
The Saccharomyces cerevisiae 14-3-3 proteins are required for the G 1/S transition, actin cytoskeleton organization and cell wall integrity 188
The Saccharomyces cerevisiae Sae2 protein negatively regulates DNA damage checkpoint signalling 187
Shelterin-like proteins and Yku inhibit nucleolytic processing of S. cerevisiae telomeres 185
The checkpoint protein Ddc2, functionally related to S. pombe Rad26, interacts with Mec1 and is regulated by Mec1-dependent phosphorylation in budding yeast. 184
Role of the Saccharomyces cerevisiae Rad53 checkpoint kinase in signaling double-strand breaks during the meiotic cell cycle. 182
A central role for DNA replication forks in checkpoint activation and response 176
Sudden telomere lengthening triggers a Rad53-dependent checkpoint in Saccharomyces cerevisiae 176
PP2A Controls Genome Integrity by Integrating Nutrient-Sensing and Metabolic Pathways with the DNA Damage Response 174
Sae2 and Rif2 regulate MRX endonuclease activity at DNA double-strand breaks in opposite manners 172
The set1Δ mutation unveils a novel signaling pathway relayed by the Rad53-dependent hyperphosphorylation of replication protein A that leads to transcriptional activation of repair genes 171
MRX-dependent DNA damage response to short telomeres 171
Irreparable telomeric DNA damage and persistent DDR signalling as a shared causative mechanism of cellular senescence and ageing 171
The chromatin remodeler Chd1 supports MRX and Exo1 functions in resection of DNA double-strand breaks 167
Interplay between Sae2 and Rif2 in the regulation of Mre11-Rad50 activities at DNA ends 165
DNA damage response at functional and dysfunctional telomeres 162
The Ku complex promotes DNA end-bridging and this function is antagonized by Tel1/ATM kinase 161
The Mec1p and Tel1p checkpoint kinases allow humanized yeast to tolerate chronic telomere dysfunctions by suppressing telomere fusions 161
Telomere-end processing: mechanisms and regulation 161
Rif2 interaction with Rad50 counteracts Tel1 functions in checkpoint signalling and DNA tethering by releasing Tel1 from MRX binding 157
Dephosphorylation of γH2A by Gcl7/Protein Phosphatase 1 promotes recovery from inhibition of DNA replication 157
Functions of Saccharomyces cerevisiae 14-3-3 proteins in response to DNA damage and to DNA replication stress 154
Dominant TEL1-hy mutations compensate for Mec1 lack of functions in the DNA damage response 154
The role of shelterin in maintaining telomere integrity 148
Regulation of the DNA damage response by cyclin-dependent kinases 145
To Fix or Not to Fix: Maintenance of Chromosome Ends Versus Repair of DNA Double-Strand Breaks 140
The Rad53CHK1/CHK2-Spt21NPAT and Tel1ATM axes couple glucose tolerance to histone dosage and subtelomeric silencing 133
The DNA damage checkpoint: A tale from budding yeast 130
Checkpoint proteins influence telomeric silencing and length maintenance in budding yeast. 130
The PP2A phosphatase counteracts the function of the 9-1-1 axis in checkpoint activation 127
Exo1 cooperates with Tel1/ATM in promoting recombination events at DNA replication forks 102
Proteasome-mediated degradation of long-range nucleases negatively regulates resection of DNA double-strand breaks 91
Functional and molecular insights into the role of Sae2 C-terminus in the activation of MRX endonuclease 60
Multi-pathway blood biomarkers to target and monitor multidimensional prevention of cognitive and functional decline (nested in the IN-TeMPO study framed within the world-wide FINGERS network) 30
Checkpoint activation and recovery: regulation of the 9–1–1 axis by the PP2A phosphatase 12
Totale 20.577
Categoria #
all - tutte 63.075
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 63.075


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/202082 0 0 0 0 0 0 0 0 0 0 0 82
2020/20212.901 114 119 264 288 243 278 244 245 239 344 168 355
2021/20221.907 167 214 296 200 125 147 107 95 64 88 179 225
2022/20232.737 281 782 283 295 181 367 32 147 196 36 102 35
2023/20241.740 61 71 46 124 190 419 299 194 112 26 41 157
2024/20253.603 185 327 245 173 265 169 261 134 269 769 339 467
Totale 20.577