Bicocca Open Archive

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LONGHESE, MARIA PIA
 Distribuzione geografica
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Continente #
NA - Nord America 10.330
EU - Europa 6.771
AS - Asia 2.068
SA - Sud America 106
AF - Africa 21
Continente sconosciuto - Info sul continente non disponibili 7
OC - Oceania 4
Totale 19.307
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Nazione #
US - Stati Uniti d'America 10.172
IT - Italia 1.852
DE - Germania 952
RU - Federazione Russa 760
SE - Svezia 718
CN - Cina 666
SG - Singapore 632
PL - Polonia 606
IE - Irlanda 387
UA - Ucraina 330
FR - Francia 329
HK - Hong Kong 293
GB - Regno Unito 292
VN - Vietnam 165
CA - Canada 152
AT - Austria 140
FI - Finlandia 124
IN - India 109
DK - Danimarca 99
BR - Brasile 88
NL - Olanda 88
TR - Turchia 75
ID - Indonesia 68
BE - Belgio 40
CH - Svizzera 10
ES - Italia 10
JP - Giappone 10
ZA - Sudafrica 10
GR - Grecia 7
AR - Argentina 6
EU - Europa 6
PK - Pakistan 6
UZ - Uzbekistan 6
BD - Bangladesh 5
CZ - Repubblica Ceca 5
IR - Iran 5
MX - Messico 5
AZ - Azerbaigian 4
MA - Marocco 4
PT - Portogallo 4
RS - Serbia 4
SC - Seychelles 4
AU - Australia 3
BG - Bulgaria 3
EC - Ecuador 3
IL - Israele 3
KZ - Kazakistan 3
PE - Perù 3
PH - Filippine 3
CO - Colombia 2
IQ - Iraq 2
KR - Corea 2
MU - Mauritius 2
MY - Malesia 2
NO - Norvegia 2
PY - Paraguay 2
TW - Taiwan 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AE - Emirati Arabi Uniti 1
CL - Cile 1
CY - Cipro 1
EG - Egitto 1
GE - Georgia 1
HR - Croazia 1
HU - Ungheria 1
IS - Islanda 1
JO - Giordania 1
KW - Kuwait 1
LT - Lituania 1
LV - Lettonia 1
MD - Moldavia 1
MK - Macedonia 1
NZ - Nuova Zelanda 1
PA - Panama 1
PS - Palestinian Territory 1
RO - Romania 1
SK - Slovacchia (Repubblica Slovacca) 1
TH - Thailandia 1
VE - Venezuela 1
Totale 19.307
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Città #
Ann Arbor 2.426
Fairfield 931
Woodbridge 815
Ashburn 698
Milan 681
Chandler 659
Houston 649
Frankfurt am Main 642
Wilmington 603
Kraków 594
Singapore 447
Dublin 375
Seattle 366
Jacksonville 361
Hong Kong 290
Cambridge 278
Dearborn 258
New York 213
Santa Clara 209
Princeton 164
Vienna 134
Dong Ket 128
Nanjing 117
Moscow 108
Altamura 92
Shanghai 90
Lawrence 81
Jakarta 65
San Diego 64
Council Bluffs 61
Lachine 55
Fremont 54
Guangzhou 54
Helsinki 50
Nanchang 48
Rome 48
Beijing 47
Boardman 45
Los Angeles 42
Brussels 39
Ottawa 37
Toronto 30
Andover 29
Hebei 29
Hefei 29
Munich 28
Botticino 26
Huizen 26
Jinan 26
London 23
Kunming 22
Shenyang 21
Capralba 19
Falls Church 19
Zhengzhou 19
Seveso 18
Changsha 17
Chicago 17
Cuggiono 17
Tianjin 17
Brescia 16
Nuremberg 16
Philadelphia 16
Sacramento 16
Cinisello Balsamo 15
Edmonton 15
Jiaxing 15
Düsseldorf 14
Taizhou 14
Auburn Hills 13
Montpellier 13
Mountain View 13
Novate Milanese 13
Sesto San Giovanni 13
Vedano al Lambro 13
Bonndorf 12
Kiev 12
Ningbo 12
Norwalk 11
Dallas 10
Pavia 10
Rossiglione 10
Seregno 10
New Delhi 9
Romola 9
Stockholm 9
São Paulo 9
Bologna 8
Grafing 8
Hangzhou 8
Leawood 8
Santa Cruz 8
Tappahannock 8
Torino 8
Turku 8
Verona 8
Changchun 7
Citta Sant'angelo 7
Como 7
Hyderabad 7
Totale 13.988
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Nome #
Structure–function relationships of the Mre11 protein in the control of DNA end bridging and processing 463
Sae2 Function at DNA Double-Strand Breaks Is Bypassed by Dampening Tel1 or Rad53 Activity 441
DNA binding modes influence Rap1 activity in the regulation of telomere length and MRX functions at DNA ends 432
Uncoupling Sae2 functions in downregulation of Tel1 and Rad53 signaling activities 423
The MRX complex regulates Exo1 resection activity by altering DNA end structure 408
Tel1/ATM Signaling to the Checkpoint Contributes to Replicative Senescence in the Absence of Telomerase 391
The ATP-bound conformation of the Mre11-Rad50 complex is essential for Tel1/ATM activation 387
Processing of DNA double-strand breaks by the MRX complex in a chromatin context 368
Structurally distinct Mre11 domains mediate MRX functions in resection, end-tethering and DNA damage resistance 356
Tel1/ATM prevents degradation of replication forks that reverse after topoisomerase poisoning 341
Rad9/53BP1 protects stalled replication forks from degradation in Mec1/ATR-defective cells 324
Tel1 and Rif2 Regulate MRX Functions in End-Tethering and Repair of DNA Double-Strand Breaks 323
Regulation of telomere metabolism by the RNA processing protein Xrn1 302
Resection of a DNA Double-Strand Break by Alkaline Gel Electrophoresis and Southern Blotting 300
Local unwinding of double-strand DNA ends by the MRX complex promotes Exo1 processing activity 299
Escape of Sgs1 from Rad9 inhibition reduces the requirement for Sae2 and functional MRX in DNA end resection 287
Functions and regulation of the MRX complex at DNA double-strand breaks 285
Coupling end resection with the checkpoint response at DNA double-strand breaks 283
Processing of DNA ends in the maintenance of genome stability 278
DNA double-strand breaks in meiosis: Checking their formation, processing and repair 267
Sensing R-Loop-Associated DNA Damage to Safeguard Genome Stability 267
Distinct Cdk1 requirements during single-strand annealing, noncrossover and crossover recombination 258
Tbf1 and Vid22 promote resection and non-homologous end joining of DNA double-strand break ends. 254
The RNA binding protein Npl3 promotes resection of DNA double-strand breaks by regulating the levels of Exo1 254
The regulation of the DNA damage response at telomeres: Focus on kinases 248
The 9-1-1 Complex Controls Mre11 Nuclease and Checkpoint Activation during Short-Range Resection of DNA Double-Strand Breaks 243
The Saccharomyces cerevisiae Sae2 protein promotes resection and bridging of double strand break ends 241
A balance between Tel1 and Rif2 activities regulates nucleolytic processing and elongation at telomeres 239
G(1)/S and G(2)/M cyclin-dependent kinase activities commit cells to death in the absence of the S-phase checkpoint. 237
Resection is responsible for loss of transcription around a double-strand break in Saccharomyces cerevisiae 235
A Tel1/MRX-dependent checkpoint inhibits the metaphase-to-anaphase transition after UV irradiation in the absence of Mec1 234
The MRX complex plays multiple functions in resection of Yku- and Rif2-protected DNA ends 229
Mechanisms and regulation of DNA end resection 229
Interplays between ATM/Tel1 and ATR/Mec1 in sensing and signaling DNA double-strand breaks 226
Telomeres and DNA damage checkpoints 224
RNA-processing proteins regulate Mec1/ATR activation by promoting generation of RPA-coated ssDNA 223
Processing of meiotic DNA double strand breaks requires cyclin-dependent kinase and multiple nucleases 221
Rif1 supports the function of the CST complex in yeast telomere capping 221
The cellular response to chromosome breakage 220
Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation. 219
Hyperactivation of the yeast DNA damage checkpoint by TEL1 and DDC2 overexpression 217
How do cells sense DNA lesions? 217
The Yku70-Yku80 complex contributes to regulate double-strand break processing and checkpoint activation during the cell cycle 216
Functional and structural insights into the MRX/MRN complex, a key player in recognition and repair of DNA double-strand breaks 212
Dpb4 promotes resection of DNA double-strand breaks and checkpoint activation by acting in two different protein complexes 212
Characterization of mec1 kinase-deficient mutants and of new hypomorphic mec1 alleles impairing subsets of the DNA damage response pathway 211
Multiple pathways regulate 3’ overhang generation at S. cerevisiae telomeres 211
Saccharomyces cerevisiae Rif1 cooperates with MRX-Sae2 in promoting DNA-end resection 208
Mec1/ATR regulates the generation of single-stranded DNA that attenuates Tel1/ATM signaling at DNA ends 201
functional and physical interactions between yeast 14-3-3 proteins, acetyltransferases, and deacetylases in response to DNA replication perturbations 198
The S-phase checkpoint and its regulation in Saccharomyces cerevisiae 198
Physical and functional interactions between nucleotide excision repair and DNA damage checkpoint 195
Surveillance mechanisms monitoring chromosome breaks during mitosis and meiosis 194
The General Regulatory Factor Tbf1 and its interacting protein Vid22 promote repair of DNA double-strand breaks 191
Budding yeast Sae2 is an in vivo target of the Mec1 and Tel1 checkpoint kinases during meiosis 190
Dual role for Saccharomyces cerevisiae Tel1 in the checkpoint response to double-strand breaks. 189
RPA regulates telomerase action by providing Est1p access to chromosome ends 188
The functions of budding yeast Sae2 in the DNA damage response require Mec1- and Tel1-dependent phosphorylation 186
The Saccharomyces cerevisiae 14-3-3 proteins are required for the G 1/S transition, actin cytoskeleton organization and cell wall integrity 185
The Saccharomyces cerevisiae Sae2 protein negatively regulates DNA damage checkpoint signalling 180
Shelterin-like proteins and Yku inhibit nucleolytic processing of S. cerevisiae telomeres 180
The checkpoint protein Ddc2, functionally related to S. pombe Rad26, interacts with Mec1 and is regulated by Mec1-dependent phosphorylation in budding yeast. 179
Role of the Saccharomyces cerevisiae Rad53 checkpoint kinase in signaling double-strand breaks during the meiotic cell cycle. 177
Sudden telomere lengthening triggers a Rad53-dependent checkpoint in Saccharomyces cerevisiae 172
A central role for DNA replication forks in checkpoint activation and response 169
Sae2 and Rif2 regulate MRX endonuclease activity at DNA double-strand breaks in opposite manners 167
MRX-dependent DNA damage response to short telomeres 166
Irreparable telomeric DNA damage and persistent DDR signalling as a shared causative mechanism of cellular senescence and ageing 166
PP2A Controls Genome Integrity by Integrating Nutrient-Sensing and Metabolic Pathways with the DNA Damage Response 166
The set1Δ mutation unveils a novel signaling pathway relayed by the Rad53-dependent hyperphosphorylation of replication protein A that leads to transcriptional activation of repair genes 165
Interplay between Sae2 and Rif2 in the regulation of Mre11-Rad50 activities at DNA ends 160
Telomere-end processing: mechanisms and regulation 159
The chromatin remodeler Chd1 supports MRX and Exo1 functions in resection of DNA double-strand breaks 159
DNA damage response at functional and dysfunctional telomeres 157
The Mec1p and Tel1p checkpoint kinases allow humanized yeast to tolerate chronic telomere dysfunctions by suppressing telomere fusions 156
The Ku complex promotes DNA end-bridging and this function is antagonized by Tel1/ATM kinase 153
Dephosphorylation of γH2A by Gcl7/Protein Phosphatase 1 promotes recovery from inhibition of DNA replication 153
Dominant TEL1-hy mutations compensate for Mec1 lack of functions in the DNA damage response 152
Rif2 interaction with Rad50 counteracts Tel1 functions in checkpoint signalling and DNA tethering by releasing Tel1 from MRX binding 150
Functions of Saccharomyces cerevisiae 14-3-3 proteins in response to DNA damage and to DNA replication stress 149
The role of shelterin in maintaining telomere integrity 146
Regulation of the DNA damage response by cyclin-dependent kinases 143
To Fix or Not to Fix: Maintenance of Chromosome Ends Versus Repair of DNA Double-Strand Breaks 135
The Rad53CHK1/CHK2-Spt21NPAT and Tel1ATM axes couple glucose tolerance to histone dosage and subtelomeric silencing 129
The DNA damage checkpoint: A tale from budding yeast 124
Checkpoint proteins influence telomeric silencing and length maintenance in budding yeast. 123
The PP2A phosphatase counteracts the function of the 9-1-1 axis in checkpoint activation 122
Exo1 cooperates with Tel1/ATM in promoting recombination events at DNA replication forks 97
Proteasome-mediated degradation of long-range nucleases negatively regulates resection of DNA double-strand breaks 85
Functional and molecular insights into the role of Sae2 C-terminus in the activation of MRX endonuclease 54
Multi-pathway blood biomarkers to target and monitor multidimensional prevention of cognitive and functional decline (nested in the IN-TeMPO study framed within the world-wide FINGERS network) 13
Totale 20.105
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Categoria #
all - tutte 62.085
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 62.085
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020276 0 0 0 0 0 0 0 0 0 0 194 82
2020/20212.901 114 119 264 288 243 278 244 245 239 344 168 355
2021/20221.907 167 214 296 200 125 147 107 95 64 88 179 225
2022/20232.737 281 782 283 295 181 367 32 147 196 36 102 35
2023/20241.740 61 71 46 124 190 419 299 194 112 26 41 157
2024/20253.131 185 327 245 173 265 169 261 134 269 769 334 0
Totale 20.105