LONGHESE, MARIA PIA
 Distribuzione geografica
Continente #
NA - Nord America 15.410
EU - Europa 10.141
AS - Asia 6.662
Continente sconosciuto - Info sul continente non disponibili 838
SA - Sud America 837
AF - Africa 148
OC - Oceania 7
Totale 34.043
Nazione #
US - Stati Uniti d'America 14.711
IT - Italia 2.744
SE - Svezia 2.617
SG - Singapore 2.031
CN - Cina 1.682
VN - Vietnam 1.023
DE - Germania 1.002
RU - Federazione Russa 785
HK - Hong Kong 778
PL - Polonia 641
BR - Brasile 626
CA - Canada 578
FR - Francia 433
GB - Regno Unito 413
IE - Irlanda 397
UA - Ucraina 345
IN - India 273
FI - Finlandia 153
BD - Bangladesh 151
AT - Austria 149
NL - Olanda 139
TR - Turchia 117
ID - Indonesia 105
DK - Danimarca 103
KR - Corea 97
AR - Argentina 70
IQ - Iraq 69
MX - Messico 62
ZA - Sudafrica 60
ES - Italia 53
CH - Svizzera 46
JP - Giappone 42
SA - Arabia Saudita 41
BE - Belgio 40
EC - Ecuador 40
PK - Pakistan 37
PH - Filippine 36
UZ - Uzbekistan 32
CO - Colombia 30
VE - Venezuela 26
AE - Emirati Arabi Uniti 17
MA - Marocco 16
EG - Egitto 15
AZ - Azerbaigian 14
OM - Oman 14
MY - Malesia 13
JM - Giamaica 12
KZ - Kazakistan 12
NP - Nepal 12
CL - Cile 11
PE - Perù 11
JO - Giordania 10
KE - Kenya 10
IL - Israele 9
LT - Lituania 9
PY - Paraguay 9
RS - Serbia 9
UY - Uruguay 9
BG - Bulgaria 8
CR - Costa Rica 8
DO - Repubblica Dominicana 8
ET - Etiopia 8
TN - Tunisia 8
CZ - Repubblica Ceca 7
GR - Grecia 7
HN - Honduras 7
IR - Iran 7
PS - Palestinian Territory 7
TH - Thailandia 7
AU - Australia 6
EU - Europa 6
KG - Kirghizistan 6
PT - Portogallo 6
RO - Romania 6
TT - Trinidad e Tobago 6
DZ - Algeria 5
HU - Ungheria 4
SC - Seychelles 4
SK - Slovacchia (Repubblica Slovacca) 4
TW - Taiwan 4
GT - Guatemala 3
HR - Croazia 3
MD - Moldavia 3
MU - Mauritius 3
PA - Panama 3
SN - Senegal 3
SV - El Salvador 3
AL - Albania 2
AO - Angola 2
BA - Bosnia-Erzegovina 2
BB - Barbados 2
BH - Bahrain 2
BN - Brunei Darussalam 2
BO - Bolivia 2
BS - Bahamas 2
CI - Costa d'Avorio 2
CY - Cipro 2
EE - Estonia 2
GD - Grenada 2
GE - Georgia 2
Totale 33.175
Città #
Ann Arbor 2.426
Stockholm 1.891
Ashburn 1.783
Singapore 1.217
Milan 978
Fairfield 933
Woodbridge 816
San Jose 798
Hong Kong 757
Houston 675
Frankfurt am Main 660
Chandler 659
Wilmington 605
Kraków 594
Dublin 382
Toronto 382
Seattle 376
Jacksonville 364
New York 319
Cambridge 280
Ho Chi Minh City 280
Santa Clara 267
Los Angeles 263
Dearborn 258
Council Bluffs 240
Beijing 239
Hanoi 197
Hefei 182
Princeton 167
Chicago 157
Dallas 156
Rome 140
Vienna 138
Boardman 131
Dong Ket 128
Nanjing 117
The Dalles 116
Columbus 111
Moscow 110
Shanghai 98
Buffalo 93
Altamura 92
Seoul 91
Lauterbourg 82
Lawrence 81
Jakarta 72
Guangzhou 68
San Diego 65
São Paulo 63
Helsinki 59
Lachine 55
Fremont 54
Munich 53
London 50
Nanchang 48
Montreal 47
Phoenix 41
Zurich 40
Brussels 39
Orem 39
Atlanta 38
Brooklyn 38
Da Nang 38
Ottawa 38
Johannesburg 35
Haiphong 32
Andover 30
Tokyo 30
Warsaw 30
Denver 29
Hebei 29
Philadelphia 29
New Delhi 28
Baghdad 27
Jinan 27
Botticino 26
Changsha 26
Huizen 26
Salt Lake City 26
Seveso 26
Tashkent 26
Chennai 25
Mexico City 23
Shenyang 23
Tianjin 23
Kunming 22
Poplar 21
Tampa 21
Zhengzhou 21
Amsterdam 20
Brescia 20
San Francisco 20
Sesto San Giovanni 20
Capralba 19
Falls Church 19
Mumbai 19
Turku 19
Biên Hòa 18
Manchester 18
Nuremberg 18
Totale 22.645
Nome #
Sae2 integrates CDK and checkpoint phosphorylation to coordinate MRX cleavage with checkpoint attenuation 1.982
Structure–function relationships of the Mre11 protein in the control of DNA end bridging and processing 609
DNA binding modes influence Rap1 activity in the regulation of telomere length and MRX functions at DNA ends 586
Sae2 Function at DNA Double-Strand Breaks Is Bypassed by Dampening Tel1 or Rad53 Activity 584
The MRX complex regulates Exo1 resection activity by altering DNA end structure 546
Uncoupling Sae2 functions in downregulation of Tel1 and Rad53 signaling activities 546
The ATP-bound conformation of the Mre11-Rad50 complex is essential for Tel1/ATM activation 535
Tel1/ATM Signaling to the Checkpoint Contributes to Replicative Senescence in the Absence of Telomerase 527
Processing of DNA double-strand breaks by the MRX complex in a chromatin context 491
Exo1 cooperates with Tel1/ATM in promoting recombination events at DNA replication forks 490
Structurally distinct Mre11 domains mediate MRX functions in resection, end-tethering and DNA damage resistance 486
Tel1 and Rif2 Regulate MRX Functions in End-Tethering and Repair of DNA Double-Strand Breaks 469
Rad9/53BP1 protects stalled replication forks from degradation in Mec1/ATR-defective cells 461
Tel1/ATM prevents degradation of replication forks that reverse after topoisomerase poisoning 448
Escape of Sgs1 from Rad9 inhibition reduces the requirement for Sae2 and functional MRX in DNA end resection 442
The regulation of the DNA damage response at telomeres: Focus on kinases 441
Coupling end resection with the checkpoint response at DNA double-strand breaks 437
Functions and regulation of the MRX complex at DNA double-strand breaks 433
Resection of a DNA Double-Strand Break by Alkaline Gel Electrophoresis and Southern Blotting 430
Regulation of telomere metabolism by the RNA processing protein Xrn1 414
DNA double-strand breaks in meiosis: Checking their formation, processing and repair 411
Sensing R-Loop-Associated DNA Damage to Safeguard Genome Stability 411
Local unwinding of double-strand DNA ends by the MRX complex promotes Exo1 processing activity 408
Processing of DNA ends in the maintenance of genome stability 404
The 9-1-1 Complex Controls Mre11 Nuclease and Checkpoint Activation during Short-Range Resection of DNA Double-Strand Breaks 401
Distinct Cdk1 requirements during single-strand annealing, noncrossover and crossover recombination 382
Functional and structural insights into the MRX/MRN complex, a key player in recognition and repair of DNA double-strand breaks 380
G(1)/S and G(2)/M cyclin-dependent kinase activities commit cells to death in the absence of the S-phase checkpoint. 371
Tbf1 and Vid22 promote resection and non-homologous end joining of DNA double-strand break ends 369
Resection is responsible for loss of transcription around a double-strand break in Saccharomyces cerevisiae 365
The MRX complex plays multiple functions in resection of Yku- and Rif2-protected DNA ends 362
How do cells sense DNA lesions? 361
Dpb4 promotes resection of DNA double-strand breaks and checkpoint activation by acting in two different protein complexes 357
The RNA binding protein Npl3 promotes resection of DNA double-strand breaks by regulating the levels of Exo1 356
Mechanisms and regulation of DNA end resection 355
A balance between Tel1 and Rif2 activities regulates nucleolytic processing and elongation at telomeres 353
A Tel1/MRX-dependent checkpoint inhibits the metaphase-to-anaphase transition after UV irradiation in the absence of Mec1 343
RNA-processing proteins regulate Mec1/ATR activation by promoting generation of RPA-coated ssDNA 340
Rif2 interaction with Rad50 counteracts Tel1 functions in checkpoint signalling and DNA tethering by releasing Tel1 from MRX binding 338
Interplays between ATM/Tel1 and ATR/Mec1 in sensing and signaling DNA double-strand breaks 338
Rif1 supports the function of the CST complex in yeast telomere capping 337
The S-phase checkpoint and its regulation in Saccharomyces cerevisiae 336
The Saccharomyces cerevisiae Sae2 protein promotes resection and bridging of double strand break ends 336
Saccharomyces cerevisiae Rif1 cooperates with MRX-Sae2 in promoting DNA-end resection 332
Sae2 and Rif2 regulate MRX endonuclease activity at DNA double-strand breaks in opposite manners 324
Hyperactivation of the yeast DNA damage checkpoint by TEL1 and DDC2 overexpression 322
The chromatin remodeler Chd1 supports MRX and Exo1 functions in resection of DNA double-strand breaks 318
Telomeres and DNA damage checkpoints 316
Multi-pathway blood biomarkers to target and monitor multidimensional prevention of cognitive and functional decline (nested in the IN-TeMPO study framed within the world-wide FINGERS network) 314
Processing of meiotic DNA double strand breaks requires cyclin-dependent kinase and multiple nucleases 314
The PP2A phosphatase counteracts the function of the 9-1-1 axis in checkpoint activation 310
The cellular response to chromosome breakage 310
Functional and molecular insights into the role of Sae2 C-terminus in the activation of MRX endonuclease 308
The Ku complex promotes DNA end-bridging and this function is antagonized by Tel1/ATM kinase 307
Multiple pathways regulate 3’ overhang generation at S. cerevisiae telomeres 306
Characterization of mec1 kinase-deficient mutants and of new hypomorphic mec1 alleles impairing subsets of the DNA damage response pathway 305
The Yku70-Yku80 complex contributes to regulate double-strand break processing and checkpoint activation during the cell cycle 304
To Fix or Not to Fix: Maintenance of Chromosome Ends Versus Repair of DNA Double-Strand Breaks 304
Mec1/ATR regulates the generation of single-stranded DNA that attenuates Tel1/ATM signaling at DNA ends 303
Interplay between Sae2 and Rif2 in the regulation of Mre11-Rad50 activities at DNA ends 303
Surveillance mechanisms monitoring chromosome breaks during mitosis and meiosis 297
Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation. 296
functional and physical interactions between yeast 14-3-3 proteins, acetyltransferases, and deacetylases in response to DNA replication perturbations 294
The General Regulatory Factor Tbf1 and its interacting protein Vid22 promote repair of DNA double-strand breaks 293
Role of the Saccharomyces cerevisiae Rad53 checkpoint kinase in signaling double-strand breaks during the meiotic cell cycle. 292
Shelterin-like proteins and Yku inhibit nucleolytic processing of S. cerevisiae telomeres 291
PP2A Controls Genome Integrity by Integrating Nutrient-Sensing and Metabolic Pathways with the DNA Damage Response 291
Physical and functional interactions between nucleotide excision repair and DNA damage checkpoint 286
The Saccharomyces cerevisiae 14-3-3 proteins are required for the G 1/S transition, actin cytoskeleton organization and cell wall integrity 285
Dual role for Saccharomyces cerevisiae Tel1 in the checkpoint response to double-strand breaks. 284
The Saccharomyces cerevisiae Sae2 protein negatively regulates DNA damage checkpoint signalling 280
The DNA damage checkpoint: A tale from budding yeast 279
RPA regulates telomerase action by providing Est1p access to chromosome ends 279
The checkpoint protein Ddc2, functionally related to S. pombe Rad26, interacts with Mec1 and is regulated by Mec1-dependent phosphorylation in budding yeast. 277
The set1Δ mutation unveils a novel signaling pathway relayed by the Rad53-dependent hyperphosphorylation of replication protein A that leads to transcriptional activation of repair genes 270
Dominant TEL1-hy mutations compensate for Mec1 lack of functions in the DNA damage response 268
Dephosphorylation of γH2A by Gcl7/Protein Phosphatase 1 promotes recovery from inhibition of DNA replication 266
Sudden telomere lengthening triggers a Rad53-dependent checkpoint in Saccharomyces cerevisiae 264
A central role for DNA replication forks in checkpoint activation and response 262
The functions of budding yeast Sae2 in the DNA damage response require Mec1- and Tel1-dependent phosphorylation 262
Budding yeast Sae2 is an in vivo target of the Mec1 and Tel1 checkpoint kinases during meiosis 258
MRX-dependent DNA damage response to short telomeres 256
DNA damage response at functional and dysfunctional telomeres 241
Irreparable telomeric DNA damage and persistent DDR signalling as a shared causative mechanism of cellular senescence and ageing 241
The role of shelterin in maintaining telomere integrity 240
Proteasome-mediated degradation of long-range nucleases negatively regulates resection of DNA double-strand breaks 238
Telomere-end processing: mechanisms and regulation 237
Functions of Saccharomyces cerevisiae 14-3-3 proteins in response to DNA damage and to DNA replication stress 233
The Mec1p and Tel1p checkpoint kinases allow humanized yeast to tolerate chronic telomere dysfunctions by suppressing telomere fusions 233
Checkpoint proteins influence telomeric silencing and length maintenance in budding yeast. 218
Checkpoint activation and recovery: regulation of the 9–1–1 axis by the PP2A phosphatase 214
Regulation of the DNA damage response by cyclin-dependent kinases 209
Stn1 supports Mec1 function in protecting stalled replication forks from degradation 204
The Rad53CHK1/CHK2-Spt21NPAT and Tel1ATM axes couple glucose tolerance to histone dosage and subtelomeric silencing 195
Stn1 supports Mec1 function in protecting stalled replication forks from degradation 36
Stn1 supports Mec1 function in protecting stalled replication forks from degradation 26
Exploring the function of the CST complex at DNA double-strand breaks 24
Exploring the functions of the CST complex in the DNA damage response 19
Stn1 supports Mec1 function in protecting stalled replication forks from degradation 18
Exploring the function of the CST complex at DNA double-strand breaks 16
Totale 34.043
Categoria #
all - tutte 95.382
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 95.382


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.526 0 0 296 200 125 147 107 95 64 88 179 225
2022/20232.737 281 782 283 295 181 367 32 147 196 36 102 35
2023/20241.740 61 71 46 124 190 419 299 194 112 26 41 157
2024/20253.724 185 327 245 173 265 169 261 134 269 769 339 588
2025/202612.168 1.053 662 692 1.208 1.206 542 1.381 506 836 2.766 597 719
2026/20271.177 239 497 441 0 0 0 0 0 0 0 0 0
Totale 34.043