LONGHESE, MARIA PIA
 Distribuzione geografica
Continente #
NA - Nord America 9.449
EU - Europa 5.477
AS - Asia 1.068
SA - Sud America 8
AF - Africa 7
Continente sconosciuto - Info sul continente non disponibili 7
OC - Oceania 4
Totale 16.020
Nazione #
US - Stati Uniti d'America 9.303
IT - Italia 1.545
DE - Germania 853
SE - Svezia 717
PL - Polonia 598
CN - Cina 557
IE - Irlanda 386
UA - Ucraina 317
FR - Francia 288
GB - Regno Unito 277
VN - Vietnam 161
HK - Hong Kong 146
CA - Canada 145
AT - Austria 128
FI - Finlandia 102
DK - Danimarca 97
IN - India 94
TR - Turchia 69
RU - Federazione Russa 61
BE - Belgio 39
NL - Olanda 38
SG - Singapore 10
JP - Giappone 9
CH - Svizzera 7
EU - Europa 6
BR - Brasile 5
GR - Grecia 5
IR - Iran 5
CZ - Repubblica Ceca 4
RS - Serbia 4
SC - Seychelles 4
AU - Australia 3
ID - Indonesia 3
PE - Perù 3
PK - Pakistan 3
PT - Portogallo 3
BG - Bulgaria 2
IL - Israele 2
KR - Corea 2
MU - Mauritius 2
MY - Malesia 2
TW - Taiwan 2
A2 - ???statistics.table.value.countryCode.A2??? 1
HU - Ungheria 1
IQ - Iraq 1
KW - Kuwait 1
KZ - Kazakistan 1
LV - Lettonia 1
MD - Moldavia 1
MK - Macedonia 1
MX - Messico 1
NO - Norvegia 1
NZ - Nuova Zelanda 1
RO - Romania 1
ZA - Sudafrica 1
Totale 16.020
Città #
Ann Arbor 2.426
Fairfield 931
Woodbridge 815
Chandler 659
Houston 649
Frankfurt am Main 622
Wilmington 603
Kraków 594
Milan 557
Ashburn 500
Dublin 374
Seattle 362
Jacksonville 361
Cambridge 278
Dearborn 258
New York 210
Princeton 164
Hong Kong 146
Dong Ket 128
Vienna 127
Nanjing 117
Altamura 92
Lawrence 81
San Diego 64
Shanghai 61
Lachine 55
Fremont 54
Guangzhou 48
Nanchang 48
Rome 47
Boardman 44
Beijing 43
Helsinki 42
Brussels 38
Ottawa 36
Andover 29
Hebei 29
Toronto 28
Botticino 26
Huizen 26
Jinan 26
Los Angeles 24
London 21
Shenyang 21
Kunming 20
Capralba 19
Falls Church 19
Seveso 18
Cuggiono 17
Zhengzhou 17
Changsha 16
Philadelphia 16
Sacramento 16
Edmonton 15
Jiaxing 15
Tianjin 15
Cinisello Balsamo 14
Taizhou 14
Auburn Hills 13
Montpellier 13
Mountain View 13
Sesto San Giovanni 13
Vedano al Lambro 13
Bonndorf 12
Brescia 12
Kiev 12
Novate Milanese 12
Hefei 11
Norwalk 11
Ningbo 10
Pavia 10
Rossiglione 10
Stockholm 9
Grafing 8
Hangzhou 8
Leawood 8
New Delhi 8
Santa Cruz 8
Tappahannock 8
Torino 8
Verona 8
Changchun 7
Citta Sant'angelo 7
Dallas 7
Seregno 7
Aarhus 6
Bologna 6
Bournemouth 6
Carate Brianza 6
Giussano 6
Kocaeli 6
Maierato 6
Montréal 6
Phoenix 6
Quinzano d'Oglio 6
San Mateo 6
Serio 6
University Park 6
Washington 6
Bergamo 5
Totale 12.450
Nome #
Structure–function relationships of the Mre11 protein in the control of DNA end bridging and processing 414
Sae2 Function at DNA Double-Strand Breaks Is Bypassed by Dampening Tel1 or Rad53 Activity 404
Uncoupling Sae2 functions in downregulation of Tel1 and Rad53 signaling activities 386
DNA binding modes influence Rap1 activity in the regulation of telomere length and MRX functions at DNA ends 375
The MRX complex regulates Exo1 resection activity by altering DNA end structure 365
Tel1/ATM Signaling to the Checkpoint Contributes to Replicative Senescence in the Absence of Telomerase 364
The ATP-bound conformation of the Mre11-Rad50 complex is essential for Tel1/ATM activation 346
Processing of DNA double-strand breaks by the MRX complex in a chromatin context 320
Structurally distinct Mre11 domains mediate MRX functions in resection, end-tethering and DNA damage resistance 312
Tel1/ATM prevents degradation of replication forks that reverse after topoisomerase poisoning 298
Tel1 and Rif2 Regulate MRX Functions in End-Tethering and Repair of DNA Double-Strand Breaks 283
Resection of a DNA Double-Strand Break by Alkaline Gel Electrophoresis and Southern Blotting 272
Rad9/53BP1 protects stalled replication forks from degradation in Mec1/ATR-defective cells 271
Regulation of telomere metabolism by the RNA processing protein Xrn1 267
Local unwinding of double-strand DNA ends by the MRX complex promotes Exo1 processing activity 261
Coupling end resection with the checkpoint response at DNA double-strand breaks 251
Functions and regulation of the MRX complex at DNA double-strand breaks 245
Escape of Sgs1 from Rad9 inhibition reduces the requirement for Sae2 and functional MRX in DNA end resection 245
Processing of DNA ends in the maintenance of genome stability 231
Distinct Cdk1 requirements during single-strand annealing, noncrossover and crossover recombination 228
Sensing R-Loop-Associated DNA Damage to Safeguard Genome Stability 224
DNA double-strand breaks in meiosis: Checking their formation, processing and repair 222
The Saccharomyces cerevisiae Sae2 protein promotes resection and bridging of double strand break ends 221
The RNA binding protein Npl3 promotes resection of DNA double-strand breaks by regulating the levels of Exo1 219
Tbf1 and Vid22 promote resection and non-homologous end joining of DNA double-strand break ends. 218
A Tel1/MRX-dependent checkpoint inhibits the metaphase-to-anaphase transition after UV irradiation in the absence of Mec1 212
Telomeres and DNA damage checkpoints 209
A balance between Tel1 and Rif2 activities regulates nucleolytic processing and elongation at telomeres 204
The regulation of the DNA damage response at telomeres: Focus on kinases 202
The cellular response to chromosome breakage 199
Mechanisms and regulation of DNA end resection 199
Resection is responsible for loss of transcription around a double-strand break in Saccharomyces cerevisiae 198
The MRX complex plays multiple functions in resection of Yku- and Rif2-protected DNA ends 197
Interplays between ATM/Tel1 and ATR/Mec1 in sensing and signaling DNA double-strand breaks 197
G(1)/S and G(2)/M cyclin-dependent kinase activities commit cells to death in the absence of the S-phase checkpoint. 195
Hyperactivation of the yeast DNA damage checkpoint by TEL1 and DDC2 overexpression 192
RNA-processing proteins regulate Mec1/ATR activation by promoting generation of RPA-coated ssDNA 192
The 9-1-1 Complex Controls Mre11 Nuclease and Checkpoint Activation during Short-Range Resection of DNA Double-Strand Breaks 192
The Yku70-Yku80 complex contributes to regulate double-strand break processing and checkpoint activation during the cell cycle 189
Characterization of mec1 kinase-deficient mutants and of new hypomorphic mec1 alleles impairing subsets of the DNA damage response pathway 188
Processing of meiotic DNA double strand breaks requires cyclin-dependent kinase and multiple nucleases 188
Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation. 184
Multiple pathways regulate 3’ overhang generation at S. cerevisiae telomeres 182
How do cells sense DNA lesions? 178
Physical and functional interactions between nucleotide excision repair and DNA damage checkpoint 176
Saccharomyces cerevisiae Rif1 cooperates with MRX-Sae2 in promoting DNA-end resection 176
Surveillance mechanisms monitoring chromosome breaks during mitosis and meiosis 175
RPA regulates telomerase action by providing Est1p access to chromosome ends 171
functional and physical interactions between yeast 14-3-3 proteins, acetyltransferases, and deacetylases in response to DNA replication perturbations 170
The S-phase checkpoint and its regulation in Saccharomyces cerevisiae 169
Dual role for Saccharomyces cerevisiae Tel1 in the checkpoint response to double-strand breaks. 169
Budding yeast Sae2 is an in vivo target of the Mec1 and Tel1 checkpoint kinases during meiosis 168
Functional and structural insights into the MRX/MRN complex, a key player in recognition and repair of DNA double-strand breaks 166
The Saccharomyces cerevisiae Sae2 protein negatively regulates DNA damage checkpoint signalling 163
The Saccharomyces cerevisiae 14-3-3 proteins are required for the G 1/S transition, actin cytoskeleton organization and cell wall integrity 161
Dpb4 promotes resection of DNA double-strand breaks and checkpoint activation by acting in two different protein complexes 161
Mec1/ATR regulates the generation of single-stranded DNA that attenuates Tel1/ATM signaling at DNA ends 159
The General Regulatory Factor Tbf1 and its interacting protein Vid22 promote repair of DNA double-strand breaks 158
The checkpoint protein Ddc2, functionally related to S. pombe Rad26, interacts with Mec1 and is regulated by Mec1-dependent phosphorylation in budding yeast. 157
A central role for DNA replication forks in checkpoint activation and response 156
The functions of budding yeast Sae2 in the DNA damage response require Mec1- and Tel1-dependent phosphorylation 155
Role of the Saccharomyces cerevisiae Rad53 checkpoint kinase in signaling double-strand breaks during the meiotic cell cycle. 154
Rif1 supports the function of the CST complex in yeast telomere capping 151
Shelterin-like proteins and Yku inhibit nucleolytic processing of S. cerevisiae telomeres 148
Irreparable telomeric DNA damage and persistent DDR signalling as a shared causative mechanism of cellular senescence and ageing 146
Sudden telomere lengthening triggers a Rad53-dependent checkpoint in Saccharomyces cerevisiae 145
MRX-dependent DNA damage response to short telomeres 144
The set1Δ mutation unveils a novel signaling pathway relayed by the Rad53-dependent hyperphosphorylation of replication protein A that leads to transcriptional activation of repair genes 141
DNA damage response at functional and dysfunctional telomeres 138
The Mec1p and Tel1p checkpoint kinases allow humanized yeast to tolerate chronic telomere dysfunctions by suppressing telomere fusions 134
PP2A Controls Genome Integrity by Integrating Nutrient-Sensing and Metabolic Pathways with the DNA Damage Response 134
Telomere-end processing: mechanisms and regulation 132
Regulation of the DNA damage response by cyclin-dependent kinases 127
The role of shelterin in maintaining telomere integrity 123
Functions of Saccharomyces cerevisiae 14-3-3 proteins in response to DNA damage and to DNA replication stress 121
Dominant TEL1-hy mutations compensate for Mec1 lack of functions in the DNA damage response 118
Dephosphorylation of γH2A by Gcl7/Protein Phosphatase 1 promotes recovery from inhibition of DNA replication 116
The chromatin remodeler Chd1 supports MRX and Exo1 functions in resection of DNA double-strand breaks 114
Interplay between Sae2 and Rif2 in the regulation of Mre11-Rad50 activities at DNA ends 106
The Rad53CHK1/CHK2-Spt21NPAT and Tel1ATM axes couple glucose tolerance to histone dosage and subtelomeric silencing 105
Sae2 and Rif2 regulate MRX endonuclease activity at DNA double-strand breaks in opposite manners 103
Checkpoint proteins influence telomeric silencing and length maintenance in budding yeast. 98
To Fix or Not to Fix: Maintenance of Chromosome Ends Versus Repair of DNA Double-Strand Breaks 80
The Ku complex promotes DNA end-bridging and this function is antagonized by Tel1/ATM kinase 75
The DNA damage checkpoint: A tale from budding yeast 68
Rif2 interaction with Rad50 counteracts Tel1 functions in checkpoint signalling and DNA tethering by releasing Tel1 from MRX binding 68
The PP2A phosphatase counteracts the function of the 9-1-1 axis in checkpoint activation 48
Totale 16.786
Categoria #
all - tutte 40.915
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 40.915


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019685 0 0 0 0 0 0 0 0 0 0 316 369
2019/20203.214 299 212 229 267 290 355 427 234 281 344 194 82
2020/20212.901 114 119 264 288 243 278 244 245 239 344 168 355
2021/20221.907 167 214 296 200 125 147 107 95 64 88 179 225
2022/20232.737 281 782 283 295 181 367 32 147 196 36 102 35
2023/20241.552 61 71 46 124 190 419 299 194 112 26 10 0
Totale 16.786