Bicocca Open Archive

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LONGHESE, MARIA PIA
 Distribuzione geografica
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Continente #
NA - Nord America 14.467
EU - Europa 9.909
AS - Asia 6.603
SA - Sud America 818
AF - Africa 147
Continente sconosciuto - Info sul continente non disponibili 7
OC - Oceania 7
Totale 31.958
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Nazione #
US - Stati Uniti d'America 13.803
SE - Svezia 2.604
IT - Italia 2.552
SG - Singapore 2.028
CN - Cina 1.667
VN - Vietnam 1.015
DE - Germania 1.002
RU - Federazione Russa 785
HK - Hong Kong 777
PL - Polonia 639
BR - Brasile 620
CA - Canada 568
FR - Francia 429
GB - Regno Unito 407
IE - Irlanda 397
UA - Ucraina 345
IN - India 273
FI - Finlandia 153
AT - Austria 149
BD - Bangladesh 133
NL - Olanda 132
TR - Turchia 115
ID - Indonesia 105
DK - Danimarca 103
KR - Corea 97
IQ - Iraq 69
AR - Argentina 68
ZA - Sudafrica 60
MX - Messico 58
ES - Italia 51
CH - Svizzera 46
JP - Giappone 42
BE - Belgio 40
SA - Arabia Saudita 39
EC - Ecuador 38
PK - Pakistan 37
PH - Filippine 35
UZ - Uzbekistan 32
CO - Colombia 24
VE - Venezuela 23
AE - Emirati Arabi Uniti 16
MA - Marocco 16
EG - Egitto 15
AZ - Azerbaigian 14
OM - Oman 14
KZ - Kazakistan 12
NP - Nepal 12
CL - Cile 11
PE - Perù 11
JO - Giordania 10
KE - Kenya 10
MY - Malesia 10
IL - Israele 9
LT - Lituania 9
PY - Paraguay 9
UY - Uruguay 9
DO - Repubblica Dominicana 8
ET - Etiopia 8
RS - Serbia 8
TN - Tunisia 8
BG - Bulgaria 7
CZ - Repubblica Ceca 7
GR - Grecia 7
IR - Iran 7
JM - Giamaica 7
PS - Palestinian Territory 7
AU - Australia 6
EU - Europa 6
KG - Kirghizistan 6
DZ - Algeria 5
PT - Portogallo 5
RO - Romania 5
TT - Trinidad e Tobago 5
HN - Honduras 4
HU - Ungheria 4
SC - Seychelles 4
SK - Slovacchia (Repubblica Slovacca) 4
TH - Thailandia 4
TW - Taiwan 4
CR - Costa Rica 3
GT - Guatemala 3
HR - Croazia 3
MD - Moldavia 3
MU - Mauritius 3
PA - Panama 3
SN - Senegal 3
AO - Angola 2
BA - Bosnia-Erzegovina 2
BO - Bolivia 2
CI - Costa d'Avorio 2
CY - Cipro 2
GE - Georgia 2
GY - Guiana 2
KW - Kuwait 2
LV - Lettonia 2
LY - Libia 2
MK - Macedonia 2
MN - Mongolia 2
NO - Norvegia 2
A2 - ???statistics.table.value.countryCode.A2??? 1
Totale 31.931
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Città #
Ann Arbor 2.426
Stockholm 1.891
Ashburn 1.667
Singapore 1.217
Fairfield 933
Milan 915
Woodbridge 815
Hong Kong 757
Houston 669
Frankfurt am Main 660
Chandler 659
San Jose 658
Wilmington 605
Kraków 594
Dublin 382
Toronto 382
Seattle 374
Jacksonville 362
New York 317
Cambridge 279
Ho Chi Minh City 278
Dearborn 258
Los Angeles 257
Santa Clara 247
Beijing 237
Hanoi 194
Hefei 182
Princeton 164
Chicago 151
Dallas 150
Vienna 138
Boardman 129
Dong Ket 128
Nanjing 117
The Dalles 116
Rome 115
Moscow 110
Council Bluffs 104
Shanghai 98
Altamura 92
Buffalo 91
Seoul 91
Lauterbourg 82
Lawrence 81
Jakarta 72
Guangzhou 68
San Diego 65
São Paulo 63
Helsinki 59
Lachine 55
Fremont 54
Munich 53
London 50
Nanchang 48
Montreal 46
Zurich 40
Brussels 39
Orem 39
Da Nang 38
Ottawa 38
Columbus 37
Johannesburg 35
Atlanta 32
Haiphong 32
Brooklyn 31
Tokyo 30
Warsaw 30
Andover 29
Hebei 29
Denver 28
New Delhi 28
Baghdad 27
Botticino 26
Changsha 26
Huizen 26
Jinan 26
Seveso 26
Tashkent 26
Chennai 25
Mexico City 23
Shenyang 23
Tianjin 23
Kunming 22
Philadelphia 22
Poplar 21
Tampa 21
Zhengzhou 21
Brescia 20
San Francisco 20
Amsterdam 19
Capralba 19
Falls Church 19
Mumbai 19
Salt Lake City 19
Turku 19
Biên Hòa 18
Manchester 18
Nuremberg 18
Cuggiono 17
Guayaquil 17
Totale 21.966
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Nome #
Sae2 integrates CDK and checkpoint phosphorylation to coordinate MRX cleavage with checkpoint attenuation 1.950
Structure–function relationships of the Mre11 protein in the control of DNA end bridging and processing 597
Sae2 Function at DNA Double-Strand Breaks Is Bypassed by Dampening Tel1 or Rad53 Activity 565
DNA binding modes influence Rap1 activity in the regulation of telomere length and MRX functions at DNA ends 560
Uncoupling Sae2 functions in downregulation of Tel1 and Rad53 signaling activities 535
The MRX complex regulates Exo1 resection activity by altering DNA end structure 534
The ATP-bound conformation of the Mre11-Rad50 complex is essential for Tel1/ATM activation 524
Tel1/ATM Signaling to the Checkpoint Contributes to Replicative Senescence in the Absence of Telomerase 503
Processing of DNA double-strand breaks by the MRX complex in a chromatin context 481
Exo1 cooperates with Tel1/ATM in promoting recombination events at DNA replication forks 469
Structurally distinct Mre11 domains mediate MRX functions in resection, end-tethering and DNA damage resistance 467
Tel1 and Rif2 Regulate MRX Functions in End-Tethering and Repair of DNA Double-Strand Breaks 455
Rad9/53BP1 protects stalled replication forks from degradation in Mec1/ATR-defective cells 452
Tel1/ATM prevents degradation of replication forks that reverse after topoisomerase poisoning 436
Coupling end resection with the checkpoint response at DNA double-strand breaks 427
Escape of Sgs1 from Rad9 inhibition reduces the requirement for Sae2 and functional MRX in DNA end resection 426
The regulation of the DNA damage response at telomeres: Focus on kinases 425
Resection of a DNA Double-Strand Break by Alkaline Gel Electrophoresis and Southern Blotting 419
Functions and regulation of the MRX complex at DNA double-strand breaks 418
Regulation of telomere metabolism by the RNA processing protein Xrn1 407
Local unwinding of double-strand DNA ends by the MRX complex promotes Exo1 processing activity 403
DNA double-strand breaks in meiosis: Checking their formation, processing and repair 399
Processing of DNA ends in the maintenance of genome stability 393
Sensing R-Loop-Associated DNA Damage to Safeguard Genome Stability 391
The 9-1-1 Complex Controls Mre11 Nuclease and Checkpoint Activation during Short-Range Resection of DNA Double-Strand Breaks 390
Distinct Cdk1 requirements during single-strand annealing, noncrossover and crossover recombination 368
Functional and structural insights into the MRX/MRN complex, a key player in recognition and repair of DNA double-strand breaks 368
G(1)/S and G(2)/M cyclin-dependent kinase activities commit cells to death in the absence of the S-phase checkpoint. 367
Resection is responsible for loss of transcription around a double-strand break in Saccharomyces cerevisiae 360
Tbf1 and Vid22 promote resection and non-homologous end joining of DNA double-strand break ends 359
How do cells sense DNA lesions? 354
The MRX complex plays multiple functions in resection of Yku- and Rif2-protected DNA ends 352
A balance between Tel1 and Rif2 activities regulates nucleolytic processing and elongation at telomeres 347
Mechanisms and regulation of DNA end resection 346
The RNA binding protein Npl3 promotes resection of DNA double-strand breaks by regulating the levels of Exo1 346
Dpb4 promotes resection of DNA double-strand breaks and checkpoint activation by acting in two different protein complexes 344
A Tel1/MRX-dependent checkpoint inhibits the metaphase-to-anaphase transition after UV irradiation in the absence of Mec1 337
RNA-processing proteins regulate Mec1/ATR activation by promoting generation of RPA-coated ssDNA 334
Rif1 supports the function of the CST complex in yeast telomere capping 329
Interplays between ATM/Tel1 and ATR/Mec1 in sensing and signaling DNA double-strand breaks 328
Saccharomyces cerevisiae Rif1 cooperates with MRX-Sae2 in promoting DNA-end resection 325
Rif2 interaction with Rad50 counteracts Tel1 functions in checkpoint signalling and DNA tethering by releasing Tel1 from MRX binding 323
The Saccharomyces cerevisiae Sae2 protein promotes resection and bridging of double strand break ends 322
Hyperactivation of the yeast DNA damage checkpoint by TEL1 and DDC2 overexpression 317
The S-phase checkpoint and its regulation in Saccharomyces cerevisiae 315
Sae2 and Rif2 regulate MRX endonuclease activity at DNA double-strand breaks in opposite manners 309
Telomeres and DNA damage checkpoints 308
The cellular response to chromosome breakage 307
Processing of meiotic DNA double strand breaks requires cyclin-dependent kinase and multiple nucleases 306
Multiple pathways regulate 3’ overhang generation at S. cerevisiae telomeres 299
Characterization of mec1 kinase-deficient mutants and of new hypomorphic mec1 alleles impairing subsets of the DNA damage response pathway 297
Multi-pathway blood biomarkers to target and monitor multidimensional prevention of cognitive and functional decline (nested in the IN-TeMPO study framed within the world-wide FINGERS network) 295
The chromatin remodeler Chd1 supports MRX and Exo1 functions in resection of DNA double-strand breaks 293
The PP2A phosphatase counteracts the function of the 9-1-1 axis in checkpoint activation 292
Surveillance mechanisms monitoring chromosome breaks during mitosis and meiosis 292
Mec1/ATR regulates the generation of single-stranded DNA that attenuates Tel1/ATM signaling at DNA ends 292
The Ku complex promotes DNA end-bridging and this function is antagonized by Tel1/ATM kinase 290
Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation. 290
The Yku70-Yku80 complex contributes to regulate double-strand break processing and checkpoint activation during the cell cycle 289
Interplay between Sae2 and Rif2 in the regulation of Mre11-Rad50 activities at DNA ends 288
To Fix or Not to Fix: Maintenance of Chromosome Ends Versus Repair of DNA Double-Strand Breaks 288
functional and physical interactions between yeast 14-3-3 proteins, acetyltransferases, and deacetylases in response to DNA replication perturbations 287
Role of the Saccharomyces cerevisiae Rad53 checkpoint kinase in signaling double-strand breaks during the meiotic cell cycle. 286
PP2A Controls Genome Integrity by Integrating Nutrient-Sensing and Metabolic Pathways with the DNA Damage Response 285
Shelterin-like proteins and Yku inhibit nucleolytic processing of S. cerevisiae telomeres 281
Functional and molecular insights into the role of Sae2 C-terminus in the activation of MRX endonuclease 279
The Saccharomyces cerevisiae 14-3-3 proteins are required for the G 1/S transition, actin cytoskeleton organization and cell wall integrity 279
Dual role for Saccharomyces cerevisiae Tel1 in the checkpoint response to double-strand breaks. 278
The General Regulatory Factor Tbf1 and its interacting protein Vid22 promote repair of DNA double-strand breaks 274
Physical and functional interactions between nucleotide excision repair and DNA damage checkpoint 273
The checkpoint protein Ddc2, functionally related to S. pombe Rad26, interacts with Mec1 and is regulated by Mec1-dependent phosphorylation in budding yeast. 273
The Saccharomyces cerevisiae Sae2 protein negatively regulates DNA damage checkpoint signalling 272
RPA regulates telomerase action by providing Est1p access to chromosome ends 268
The set1Δ mutation unveils a novel signaling pathway relayed by the Rad53-dependent hyperphosphorylation of replication protein A that leads to transcriptional activation of repair genes 264
The DNA damage checkpoint: A tale from budding yeast 262
A central role for DNA replication forks in checkpoint activation and response 255
Dominant TEL1-hy mutations compensate for Mec1 lack of functions in the DNA damage response 254
Sudden telomere lengthening triggers a Rad53-dependent checkpoint in Saccharomyces cerevisiae 253
Dephosphorylation of γH2A by Gcl7/Protein Phosphatase 1 promotes recovery from inhibition of DNA replication 253
Budding yeast Sae2 is an in vivo target of the Mec1 and Tel1 checkpoint kinases during meiosis 252
The functions of budding yeast Sae2 in the DNA damage response require Mec1- and Tel1-dependent phosphorylation 252
MRX-dependent DNA damage response to short telomeres 251
DNA damage response at functional and dysfunctional telomeres 235
Irreparable telomeric DNA damage and persistent DDR signalling as a shared causative mechanism of cellular senescence and ageing 234
The role of shelterin in maintaining telomere integrity 226
Proteasome-mediated degradation of long-range nucleases negatively regulates resection of DNA double-strand breaks 224
Functions of Saccharomyces cerevisiae 14-3-3 proteins in response to DNA damage and to DNA replication stress 224
Telomere-end processing: mechanisms and regulation 220
The Mec1p and Tel1p checkpoint kinases allow humanized yeast to tolerate chronic telomere dysfunctions by suppressing telomere fusions 217
Checkpoint proteins influence telomeric silencing and length maintenance in budding yeast. 211
Regulation of the DNA damage response by cyclin-dependent kinases 202
Checkpoint activation and recovery: regulation of the 9–1–1 axis by the PP2A phosphatase 195
The Rad53CHK1/CHK2-Spt21NPAT and Tel1ATM axes couple glucose tolerance to histone dosage and subtelomeric silencing 184
Stn1 supports Mec1 function in protecting stalled replication forks from degradation 160
Totale 32.765
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Categoria #
all - tutte 89.255
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 89.255
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021355 0 0 0 0 0 0 0 0 0 0 0 355
2021/20221.907 167 214 296 200 125 147 107 95 64 88 179 225
2022/20232.737 281 782 283 295 181 367 32 147 196 36 102 35
2023/20241.740 61 71 46 124 190 419 299 194 112 26 41 157
2024/20253.724 185 327 245 173 265 169 261 134 269 769 339 588
2025/202612.067 1.053 662 692 1.208 1.206 542 1.381 506 836 2.766 597 618
Totale 32.765