DE GIOIA, LUCA
 Distribuzione geografica
Continente #
NA - Nord America 21.321
EU - Europa 11.050
AS - Asia 3.987
SA - Sud America 31
AF - Africa 18
Continente sconosciuto - Info sul continente non disponibili 13
OC - Oceania 13
Totale 36.433
Nazione #
US - Stati Uniti d'America 20.841
IT - Italia 2.284
DE - Germania 1.834
CN - Cina 1.662
SE - Svezia 1.473
IE - Irlanda 1.056
SG - Singapore 943
UA - Ucraina 928
RU - Federazione Russa 823
GB - Regno Unito 623
VN - Vietnam 564
PL - Polonia 538
CA - Canada 473
HK - Hong Kong 441
FR - Francia 320
DK - Danimarca 308
AT - Austria 299
FI - Finlandia 237
IN - India 139
NL - Olanda 132
TR - Turchia 121
BE - Belgio 76
ES - Italia 31
RO - Romania 31
ID - Indonesia 29
BR - Brasile 22
JP - Giappone 22
IR - Iran 21
CZ - Repubblica Ceca 12
NO - Norvegia 10
IL - Israele 9
PK - Pakistan 9
CH - Svizzera 8
EU - Europa 8
TW - Taiwan 8
AU - Australia 7
EG - Egitto 7
GR - Grecia 6
MX - Messico 6
NZ - Nuova Zelanda 6
BG - Bulgaria 5
CL - Cile 5
KR - Corea 5
RS - Serbia 5
A2 - ???statistics.table.value.countryCode.A2??? 4
MU - Mauritius 4
SC - Seychelles 4
AR - Argentina 3
LT - Lituania 3
AE - Emirati Arabi Uniti 2
AZ - Azerbaigian 2
HU - Ungheria 2
LB - Libano 2
LU - Lussemburgo 2
MN - Mongolia 2
A1 - Anonimo 1
AF - Afghanistan, Repubblica islamica di 1
BD - Bangladesh 1
BY - Bielorussia 1
GL - Groenlandia 1
HR - Croazia 1
KW - Kuwait 1
KZ - Kazakistan 1
LK - Sri Lanka 1
MA - Marocco 1
MY - Malesia 1
PE - Perù 1
PT - Portogallo 1
SK - Slovacchia (Repubblica Slovacca) 1
TZ - Tanzania 1
ZA - Sudafrica 1
Totale 36.433
Città #
Ann Arbor 4.881
Woodbridge 2.205
Fairfield 1.749
Wilmington 1.690
Houston 1.314
Frankfurt am Main 1.256
Chandler 1.229
Dublin 1.012
Jacksonville 1.008
Ashburn 966
Milan 858
Singapore 777
Seattle 721
Dearborn 691
Cambridge 573
Kraków 531
Hong Kong 435
Princeton 434
New York 416
Dong Ket 331
Nanjing 323
Vienna 290
Shanghai 227
Altamura 199
Lawrence 189
Lachine 168
Santa Clara 162
Beijing 145
Ottawa 140
San Diego 111
Fremont 105
Nanchang 101
Boardman 98
Guangzhou 95
Toronto 87
Shenyang 85
Hebei 81
Brussels 72
Fuzhou 67
Romola 62
Helsinki 58
Andover 55
London 51
Tianjin 49
Falls Church 47
Norwalk 47
Los Angeles 46
Rome 46
Jiaxing 45
Jinan 45
Mountain View 40
Montréal 39
Ningbo 38
Changsha 36
Hangzhou 34
Zhengzhou 34
Philadelphia 31
Huizen 30
Chicago 29
Edmonton 27
Jakarta 27
Kunming 27
Leawood 25
San Mateo 25
Grafing 24
Turin 24
Auburn Hills 23
Washington 21
Hefei 19
Kiev 16
Monmouth Junction 16
Sanayi 16
Sesto San Giovanni 16
Taizhou 16
Bergamo 15
Bologna 15
Detroit 15
Nürnberg 15
Paris 15
Pune 15
Barcelona 14
Seveso 14
Tappahannock 14
University Park 14
Modena 13
Redmond 13
Sacramento 13
Lanzhou 12
Monza 12
Brno 10
Catania 10
Changchun 10
Como 10
Dallas 10
Marseille 10
Pavia 10
Vimercate 10
Bergen 9
Carate Brianza 9
Chengdu 9
Totale 27.322
Nome #
Selective cytotoxicity of a bicyclic Ras inhibitor in cancer cells expressing K-RasG13D 557
First experimental identification of Ras-inhibitor binding interface using a water-soluble Ras ligand 529
Structure-Activity Studies on Arylamides and Arysulfonamides Ras Inhibitors 498
Structure-Activity Studies on Arylamides and Arysulfonamides Ras Inhibitors 482
The Multi-Level Mechanism of Action of a Pan-Ras Inhibitor Explains its Antiproliferative Activity on Cetuximab-Resistant Cancer Cells 432
Arabinose-derived Bicyclic Amino Acids: Synthesis, Conformational Analysis and Construction of an avb3-selective RGD Peptide 414
Rigid polycycles and peptidomimetics from carbohydrate synthons 411
Synthetic sulfoglycolipids targeting the serine–threonine protein kinase Akt 364
Design, Synthesis, and Preliminary Biological Evaluation of GlcNAc-6P Analogues for the Modulation of Phosphoacetylglucosamine Mutase 1 (AGM1/PGM3) 346
Inhibition of the Hexosamine Biosynthetic Pathway by targeting PGM3 causes breast cancer growth arrest and apoptosis 344
Theoretical study of hydration of cyanamide and carbodiimide 338
Epigallocatechin-3-gallate and related phenol compounds redirect the amyloidogenic aggregation pathway of ataxin-3 towards non-toxic aggregates and prevent toxicity in neural cells and Caenorhabditis elegans animal model 329
A theoretical study on the reactivity of the Mo/Cu-containing carbon monoxide dehydrogenase with dihydrogen 298
Anomalous Intrinsic Fluorescence of HCl and NaOH Aqueous Solutions 298
Reactivation of the Ready and Unready Oxidized States of [NiFe]-Hydrogenases: Mechanistic Insights from DFT Calculations 284
On the reactivity of the most efficient iron-based catalyst for CO2 hydrogenation: a DFT picture 280
Catalytic Mechanism of Fungal Lytic Polysaccharide Monooxygenases Investigated by First-Principles Calculations 272
Functionally relevant interplay between the Fe4S4 cluster and CN- ligands in the active site of [FeFe]-Hydrogenases 265
H2 Activation in [FeFe]-Hydrogenase Cofactor Versus Diiron Dithiolate Models: Factors Underlying the Catalytic Success of Nature and Implications for an Improved Biomimicry 248
Interaction of the H-cluster of FeFe hydrogenase with halides 238
Uncovering a Dynamically Formed Substrate Access Tunnel in Carbon Monoxide Dehydrogenase/Acetyl-CoA Synthase 237
N-Spirofused Bicyclic Derivatives of 1-Deoxynojirimycin: Synthesis and Preliminary Biological Evaluation 236
First-Principles Calculations on Ni,Fe-Containing Carbon Monoxide Dehydrogenases Reveal Key Stereoelectronic Features for Binding and Release of CO2 to/from the C-Cluster 233
Structural characterization of the nitrogenase molybdenum-iron protein with the substrate acetylene trapped near the active site 229
On the photochemistry of Fe2(edt)(CO)4(PMe3)2, a [FeFe]-hydrogenase model: A DFT/TDDFT investigation 227
Disclosure of key stereoelectronic factors for efficient H2 binding and cleavage in the active site of [NiFe]-hydrogenases 223
Rational Design of Fe2(μ-PR2)2(L)6 Coordination Compounds Featuring Tailored Potential Inversion 223
An acidic loop and cognate phosphorylation sites define a molecular switch that modulates ubiquitin charging activity in cdc34-like enzymes 222
DFT investigation of H-2 activation by [M(NHPnPr(3))(' S3 ')] (M = Ni, Pd). Insight into key factors relevant to the design of hydrogenase functional models 213
The mammalian complement system as an epitome of host-pathogen genetic conflicts 210
Theory Related to [FeFe]- and [NiFe]-hydrogenases: Stereoelectronic Properties, H-cluster Oxidation, and Mechanisms for Increasing Oxygen Tolerance 209
The Photochemistry of Fe2(S2C3H6)(CO)6(µ-CO) and Its Oxidized Form, Two Simple [FeFe]-Hydrogenase CO-Inhibited Models. A DFT and TDDFT Investigation 209
Influence of the [2Fe]H subcluster environment on the properties of key intermediates in the catalytic cycle of [FeFe] hydrogenases: Hints for the rational design of synthetic catalysts 207
A theoretical study of spin states in Ni-S-4 complexes and models of the [NiFe] hydrogenase active site 206
Intramolecular interactions stabilizing compact conformations of the intrinsically disordered kinase-inhibitor domain of Sic1: a molecular-dynamics investigation 206
Genetic analysis of polynucleotide phosphorylase structure and functions 205
A conserved loop in polynucleotide phosphorylase (PNPase) essential for both RNA and ADP/phosphate binding 205
Towards biomimetic models of the reduced [FeFe]-hydrogenase that preserve the key structural features of the enzyme active site; A DFT investigation 205
Theoretical investigation of aerobic and anaerobic oxidative inactivation of the [NiFe]-hydrogenase active site 199
On the importance of cyanide in diiron bridging carbyne complexes, unconventional [FeFe]-hydrogenase mimics without dithiolate: An electrochemical and DFT investigation 199
Investigations of the electronic-molecular structure of bio-inorganic systems using modern methods of quantum chemistry 198
On the propagation of the OH radical produced by Cu-amyloid beta peptide model complexes. Insight from molecular modelling 195
Optimization of electrostatics as a strategy for cold-adaptation: A case study of cold- and warm-active elastases 193
Application of site-directed lipase mutants on regioselective acylation of monosaccharides 191
Relevance of metal ions for lipase stability: Structural rearrangements induced in the Burkholderia glumae lipase by calcium depletion 190
A 175 Million Year History of T Cell Regulatory Molecules Reveals Widespread Selection, with Adaptive Evolution of Disease Alleles 189
Compaction Properties of an Intrinsically Disordered Protein: Sic1 and Its Kinase-Inhibitor Domain 188
Loop 7 of E2 enzymes: an ancestral conserved functional motif involved in the E2-mediated steps of the ubiquitination cascade 188
C-type natriuretic peptide: structural studies, fragment synthesis and preliminary biological evaluation in human osteosarcoma cell lines 185
Combining experimental and theoretical methods to learn about the reactivity of gas-processing metalloenzymes 185
Reciprocal influence of protein domains in the cold-adapted acyl aminoacyl peptidase from Sporosarcina psychrophila 184
Characterization of Escherichia coli uridine phosphorylase by single-site mutagenesis 183
Copper coordination to the putative cell binding site of angiogenin: a DFT investigation 183
Computational approaches to shed light on molecular mechanisms in biological processes 182
Structural and electronic properties of the [FeFe] hydrogenase H-cluster in different redox and protonation states. A DFT investigation 182
DFT Dissection of the Reduction Step in H2 Catalytic Production by [FeFe]-Hydrogenase-Inspired Models: Can the Bridging Hydride Become More Reactive Than the Terminal Isomer? 182
Quantum Mechanical Models of the Resting State of the Vanadium-Dependent Haloperoxidase 181
Dissecting the intimate mechanism of cyanation of {2Fe3S} complexes related to the active site of all-iron hydrogenases by DFT analysis of energetics, transition states, intermediates and products in the carbonyl substitution pathway 181
Computational approaches to the prediction of the redox potentials of iron and copper bioinorganic systems 180
The Importance of Stereochemically Active Lone Pairs For Influencing PbII and AsIII Protein Binding 179
Excited state properties of a [FeFe] hydrogenase active site models. The Time-Dependent Density Functional Theory theoretical picture 178
Synthesis of the H-cluster framework of iron-only hydrogenase 176
Density functional theory investigation of the active site of [Fe]-hydrogenases: Effects of redox state and ligand characteristics on structural, electronic, and reactivity properties of complexes related to the [2Fe](H) subcluster 176
DFT investigation of structural, electronic, and catalytic properties of diiron complexes related to the [2Fe]H subcluster of Fe-only hydrogenases 176
Structural investigation of the cold-adapted acylaminoacyl peptidase from Sporosarcina psychrophila by atomistic simulations and biophysical methods 176
C-terminal acidic domain of ubiquitin-conjugating enzymes: A multi-functional conserved intrinsically disordered domain in family 3 of E2 enzymes 176
Chelate control of diiron(I) dithiolates relevant to the [Fe-Fe]-hydrogenase active site 175
Mechanistic analysis of nucleophilic substrates oxidation by functional models of vanadium-dependent haloperoxidases: A density functional theory study 174
DFT investigations of models related to the active site of [NiFe] and [Fe] hydrogenases 174
Fast generation of broken-symmetry states in a large system including multiple iron-sulfur assemblies: Investigation of QM/MM energies, clusters charges, and spin populations 174
Catalytic H2 evolution/oxidation in [FeFe]-hydrogenase biomimetics: account from DFT on the interplay of related issues and proposed solutions 174
Structural insights into the active-ready form of [FeFe]-Hydrogenase and mechanistic details of its inhibition by carbon monoxide 173
Mechanistic and Physiological Implications of the Interplay among Iron-Sulfur Clusters in [FeFe]-Hydrogenases. A QM/MM Perspective 173
A sterically stabilized FeI-FeI semi-rotated conformation of [FeFe] hydrogenase subsite model 173
RIG-I-like receptors evolved adaptively in mammals, with parallel evolution at LGP2 and RIG-I 173
A new nerve growth factor-mimetic peptide active on neuropathic pain in rats 172
Dynamic Properties of a Psychrophilic alpha-Amylase in Comparison with a Mesophilic Homologue 172
Evidence for the Formation of a Mo-H Intermediate in the Catalytic Cycle of Formate Dehydrogenase 172
Quantum mechanical methods for the investigation of metalloproteins and related bioinorganic compounds 172
Speciation of Copper–Peptide Complexes in Water Solution Using DFTB and DFT Approaches: Case of the [Cu(HGGG)(Py)] Complex 171
Ni-Fe hydrogenases: A density functional theory study of active site models 170
The yeast cyclin-dependent kinase inhibitor Sic1 shares a functionally and structurally homologous domain with mammalian p27Kip1 170
Copper ion interaction with the RNase catalytic site fragment of the angiogenin protein: An experimental and theoretical investigation 170
Copper reduction and dioxygen activation in Cu-amyloid beta peptide complexes: insight from molecular modelling 169
Density functional theory investigation of guanosine triphosphate models. Catalytic role of Mg2 ions in phosphate ester hydrolysis 168
Time-dependent density functional theory study of Fe2(CO) 9 low-lying electronic excited states 168
An Evolutionary Analysis of Antigen Processing and Presentation across Different Timescales Reveals Pervasive Selection 168
Insights into the mechanism of electrocatalytic hydrogen evolution mediated by Fe2(S2C3H6)(CO)6: The simplest functional model of the Fe-hydrogenase active site 167
Excited state properties and photochemistry in [FeFe] hydrogenase research area. The Time-Dependent Density Functional Theory theoretical picture 167
DFT investigation of the CO2 activation at the active site of the Carbon Monoxide Dehydrogenases 167
Theoretical insights into [NiFe]-hydrogenases oxidation resulting in a slowly reactivating inactive state 167
New fei-fei complex featuring a rotated conformation related to [2fe]h subsite of the [fe-fe] hydrogenase 166
Protein engineering for the improvement of enzymatic activity: a site-specific mutagenesis of a lactate dehydrogenase (LDH) expressed in Saccharomyces cerevisiae 165
The oxidative inactivation of FeFe hydrogenase reveals the flexibility of the H-cluster 165
DNA-binding protects p53 from interactions with cofactors involved in transcription-independent functions 165
The cold-active lipase of Pseudomonas fragi: Heterologous expression, biochemical characterization and molecular modeling 164
Does the environment around the H-cluster allow coordination of the pendant amine to the catalytic iron center in [FeFe] hydrogenases? Answers from theory 162
Mechanistic Insight into Electrocatalytic H2 Production by [Fe2(CN)μ-CN(Me)2(μ-CO)(CO)(Cp)2]: Effects of Dithiolate Replacement in [FeFe] Hydrogenase Models 162
The reactions of pyridinyl thioesters with triiron dodecacarbonyl: their novel diiron carbonyl complexes and mechanistic investigations 161
Structural and kinetic stability of the burkholderia glumae lipase 161
Totale 22.051
Categoria #
all - tutte 115.947
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 115.947


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20204.386 0 0 0 0 570 745 953 458 581 468 410 201
2020/20215.424 406 253 441 533 432 418 385 434 399 620 270 833
2021/20223.697 293 401 503 307 175 351 271 238 181 217 281 479
2022/20235.598 665 1.631 562 579 370 785 87 260 312 65 198 84
2023/20243.610 144 108 189 229 469 784 724 179 252 75 55 402
2024/20252.352 486 840 533 472 21 0 0 0 0 0 0 0
Totale 37.714