Distribuzione geografica
Continente #
NA - Nord America 11604
EU - Europa 5606
AS - Asia 1374
Continente sconosciuto - Info sul continente non disponibili 24
SA - Sud America 21
OC - Oceania 17
AF - Africa 8
Totale 18654
Nazione #
US - Stati Uniti d'America 11268
DE - Germania 1334
SE - Svezia 1097
IT - Italia 1049
CN - Cina 1025
UA - Ucraina 661
GB - Regno Unito 399
CA - Canada 327
IE - Irlanda 146
FI - Finlandia 140
PL - Polonia 125
BE - Belgio 123
FR - Francia 115
VN - Vietnam 113
RU - Federazione Russa 105
IN - India 90
AT - Austria 83
DK - Danimarca 76
NL - Olanda 47
BG - Bulgaria 36
IR - Iran 32
TR - Turchia 31
EU - Europa 23
JP - Giappone 18
ES - Italia 16
AU - Australia 15
CH - Svizzera 14
PT - Portogallo 14
KR - Corea 13
BR - Brasile 12
RO - Romania 12
HK - Hong Kong 10
MX - Messico 8
IL - Israele 7
CL - Cile 5
ID - Indonesia 5
GR - Grecia 4
HU - Ungheria 4
MY - Malesia 4
TH - Thailandia 4
TW - Taiwan 4
AR - Argentina 3
IQ - Iraq 3
MD - Moldavia 3
MU - Mauritius 3
SG - Singapore 3
EG - Egitto 2
LB - Libano 2
NZ - Nuova Zelanda 2
PH - Filippine 2
UZ - Uzbekistan 2
ZA - Sudafrica 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AE - Emirati Arabi Uniti 1
EC - Ecuador 1
HN - Honduras 1
KW - Kuwait 1
LK - Sri Lanka 1
LU - Lussemburgo 1
MK - Macedonia 1
MO - Macao, regione amministrativa speciale della Cina 1
NO - Norvegia 1
OM - Oman 1
SA - Arabia Saudita 1
SC - Seychelles 1
Totale 18654
Città #
Ann Arbor 2237
Woodbridge 1576
Chandler 1058
Houston 863
Fairfield 832
Frankfurt am Main 817
Jacksonville 751
Wilmington 610
Dearborn 596
Milan 488
Ashburn 379
Seattle 332
Cambridge 293
Princeton 278
Nanjing 220
Beijing 166
Dublin 146
Lachine 127
Brussels 117
Kraków 114
Lawrence 110
Altamura 103
Toronto 94
Nanchang 82
Vienna 82
Hangzhou 68
Guangzhou 67
San Diego 66
Boardman 64
Ottawa 64
Dong Ket 55
Andover 51
Changsha 49
Fremont 49
Tianjin 44
Wayne 43
Philadelphia 42
Shenyang 42
Falls Church 38
Hebei 36
Jiaxing 36
Plovdiv 36
Jinan 35
Nürnberg 31
Mountain View 30
Zhengzhou 28
Auburn Hills 27
Kunming 26
Norwalk 24
Grafing 21
Ningbo 21
Rome 21
Huizen 20
Redmond 20
Chicago 17
London 16
Montréal 16
Hefei 15
Los Angeles 15
Shanghai 15
Edmonton 14
Taizhou 14
Lecco 13
Detroit 12
San Mateo 12
Monmouth Junction 11
Amsterdam 10
Fuzhou 10
Leawood 10
Segrate 10
University Park 10
Zanjan 10
Hanover 8
Kiev 8
Palermo 8
Verona 8
Cusano Milanino 7
Duncan 7
Helsinki 7
Pavia 7
Central District 6
Changchun 6
Novara 6
Pisa 6
São Paulo 6
Bangalore 5
Daejeon 5
Genova 5
Marrickville 5
San Giuliano Milanese 5
Albino 4
Augusta 4
Bologna 4
Florence 4
Hanoi 4
Madrid 4
Modena 4
Mumbai 4
Phoenix 4
Sacramento 4
Totale 14010
Nome #
Functionalization with TAT-peptide enhances blood-brain barrier crossing in vitro of nanoliposomes carrying a curcumin-derivative to bind amyloid-β peptide 355
Evolution of Nanoparticle Protein Corona across the Blood-Brain Barrier 315
Retro-inverso peptide inhibitor nanoparticles as potent inhibitors of aggregation of the Alzheimer's Aβ peptide 302
Novel Antitransferrin Receptor Antibodies Improve the Blood-Brain Barrier Crossing Efficacy of Immunoliposomes 294
Investigation of Functionalized Poly(N,N-dimethylacrylamide)-block-polystyrene Nanoparticles As Novel Drug Delivery System to Overcome the Blood-Brain Barrier in Vitro 286
Morphogenic effect of common solvent in the self-assembly behavior of amphiphilic PEO-b-PLA 249
Multifunctional liposomes interact with Abeta in human biological fluids: Therapeutic implications for Alzheimer's disease 247
Nanomedicine for the treatment of Alzheimer's disease 245
The ability of liposomes, tailored for blood-brain barrier targeting, to reach the brain is dramatically affected by the disease state 240
Modulation of the intrinsic neuronal excitability by multifunctional liposomes tailored for treatment of Alzheimer’s disease 235
Lipid-based nanoparticles counteract the oligomer abeta toxicity and tau phosphorylation in an ex-vivo biomolecular model of alzheimer disease 222
Versatile and Efficient Targeting Using a Single Nanoparticulate Platform and its Application to Cancer and Alzheimer's Disease 219
Functionalization of liposomes with ApoE-derived peptides at different density affects cellular uptake and drug transport across a blood-brain barrier model 212
Prion protein structure is affected by pH-dependent interaction with membranes: a study in a model system 204
Evaluation of gold nanoparticles biocompatibility: a multiparametric study on cultured endothelial cells and macrophages 204
TrkA pathway activation induced by amyloid-beta (Abeta) 201
18F-labeling syntheses and preclinical evaluation of functionalized nanoliposomes for Alzheimer's disease 200
Characterization of prion protein-enriched domains, isolated from rat cerebellar granule cells in culture 192
Curcumin derivatives as new ligands of Aβ peptides 188
Aβ42 production in brain capillary endothelial cells after oxygen and glucose deprivation 188
Protein-functionalized nanoparticles derived from end-functional polymers and polymer prodrugs for crossing the blood-brain barrier 186
Multifunctional liposomes delay phenotype progression and prevent memory impairment in a presymptomatic stage mouse model of Alzheimer disease 184
Effect of nanoparticles binding β-amyloid peptide on nitric oxide production by cultured endothelial cells and macrophages 176
Liposomes bi-functionalized with phosphatidic acid and an ApoE-derived peptide affect Aβ aggregation features and cross the blood-brain-barrier: Implications for therapy of Alzheimer disease 172
Membrane features and activity of GPI-anchored enzymes: alkaline phosphatase reconstituted in model membranes 171
Developmental changes in the protein composition of sphingolipid- and cholesterol-enriched membrane domains of rat cerebellar granule cells 169
Iron oxide nanoparticles surface coating and cell uptake affect biocompatibility and inflammatory responses of endothelial cells and macrophages 167
Peripheral sink effect as possible nanotherapeutic strategy for alzheimer’s disease: an ex vivo study 165
Functionalized liposomes and phytosomes loading Annona muricata L. aqueous extract: Potential nanoshuttles for brain-delivery of phenolic compounds 165
Beta Amyloid Aggregation Inhibitors: Small Molecules as Candidate Drugs for Therapy of Alzheimer Disease 162
Inhibition of murine leukemia (WEHI-3B and L1210) proliferation by cholera toxin B subunit 162
Effect of modified collagen on amyloid beta peptide aggregation 162
Immuno separation of Prion protein-enriched domains from other detergent-resistant membrane fractions, isolated from neuronal cells 161
Functionalization with ApoE-derived peptides enhances the interaction with brain capillary endothelial cells of nanoliposomes binding amyloid-beta peptide 161
Liposomes functionalized to overcome the blood–brain barrier and to target amyloid-β peptide: the chemical design affects the permeability across an in vitro model 159
Pin1, a new player in the fate of HIF-1α degradation: an hypothetical mechanism inside vascular damage as Alzheimer’s disease risk factor 159
Interactions of proteins with ganglioside-enriched microdomains on the membrane: the lateral phase separation of molecular species of GD1a ganglioside, having homogeneous long-chain base composition, is recognized by Vibrio cholerae sialidase 158
Abeta peptide toxicity is reduced after treatments decreasing phosphatidylethanolamine content in differentiated neuroblastoma cells 158
Enhanced folate binding of cultured fibroblasts from Alzheimer's disease patients 157
Pin1: a new outlook in Alzheimer's disease 156
Solid Lipid Nanoparticles: a strategy to overcome the blood-brain barrier 156
Amyposomes: a nanomedicine designed for treatment of Alzheimer disease 156
Detection and Characterization of Different Brain-Derived Subpopulations of Plasma Exosomes by Surface Plasmon Resonance Imaging 149
Abnormal cross-talk between mutant presenilin 1 (I143T, G384A) and glycosphingolipid biosynthesis 148
mApoE-Functionalized Nanoliposomes Delivering Doxorubicin and Ultrasmall Superparamagnetic Iron Oxide to Glioblastoma Cells Characterized by TEM and Confocal Microscopy 148
Fuc-GM1 ganglioside mimics the receptor function of GM1 for cholera toxin 147
Role of lipid rafts and GM1 in the segregation and processing of Prion Protein 145
Study of the effects of nanoliposomes engineered for the treatment of Alzheimer's disease on the electrical activity of cortical neurons 145
Beta-amyloid (25-35) enhances lipid metabolism and protein ubiquitination in cultured neurons 144
Pin1 affects Tau phosphorylation in response to Abeta oligomers 143
Ceramides and sphingomyelinases in senile plaques 140
Dependence of rat liver CMP-N-acetylneuraminate:GM1 sialyltransferase (SAT IV) activity on the ceramide composition of GM1 ganglioside 139
A surveillance system for early-stage diagnosis of endogenous diseases by swarms of nanobots 138
The binding affinity of anti-Aβ1-42 MAb-decorated nanoliposomes to Aβ1-42 peptides in vitro and to amyloid deposits in post-mortem tissue 138
Enhanced brain targeting of engineered solid lipid nanoparticles 138
Two tail-anchored protein variants, differing in transmembrane domain length and intracellular sorting, interact differently with lipids 137
Liposomes functionalized with acidic lipids rescue Aβ-induced toxicity in murine neuroblastoma cells 137
Role of phosphatidylethanol in membranes. Effects on membrane fluidity, tolerance to ethanol, and activity of membrane-bound enzymes 136
A photo-reactive derivative of ganglioside GM1 specifically cross-links VIP21-caveolin on the cell surface 134
Thermotropic behavior of fatty acid ethyl esters in phospholipid liposomes 134
Age-related changes in the ceramide composition of the major gangliosides present in rat brain subcellular fractions enriched in plasma membranes of neuronal and myelin origin 134
Nanotechnology for neurodegenerative disorders 134
Lipid-based nanoparticles with high binding affinity for amyloid-b1e42 peptide 132
Ischemic conditions and β-secretase activation: The impact of membrane cholesterol enrichment as triggering factor in rat brain endothelial cells 130
Multifunctional liposomes reduce brain β-amyloid burden and ameliorate memory impairment in alzheimer’s disease mouse models 130
Methyl-beta-cyclodextrin treatment affects the thermotropic behaviour of membranes and detergent-resistant membrane fractions of cultured A431 cells 129
Repeated intraperitoneal injections of liposomes containing phosphatidic acid and cardiolipin reduce amyloid-β levels in APP/PS1 transgenic mice 128
Changes in the composition of detergent-resistant membrane domains of cultured neurons following protein kinase C activation 128
Enhanced GM1 ganglioside catabolism in cultured fibroblasts from Alzheimer patients 126
Early-Stage Diagnosis of Endogenous Diseases by Swarms of Nanobots: An Applicative Scenario 126
New tricyclic compounds, process for their manufacture and their use as ligands of beta-alyloid peptides 125
Preparation and use of liposomes for the study of sphingolipid segregation in membrane model systems 125
Palmitic is the main fatty acid carried by lipids of detergent-resistant membrane fractions from neural and non-neural cells 124
Effect of curcumin-associated and lipid ligand functionalised nanoliposomes on aggregation of the Alzheimer's Aβ peptide 123
Influence of glycolipid oligosaccharide and long-chain base composition on the thermotropic properties of dipalmitoylphosphatidylcholine large unilamellar vesicles containing gangliosides 122
Attempt of neuroprotective response of rat cultured hippocampal neurons against Abeta insult 122
Lipid-based nanoparticles as a potential tool to deplete abeta. Toward new therapeutic strategies for Alzheimer’s disease? 121
Nanomedicine for the treatment of Alzheimer's disease 120
Nanotechnology for neurodegenerative disorders 119
A nanomedicine-based therapeutic approach restores memory and ameliorates amyloid pathology in Alzheimer's mouse models 117
Self-assembled electrical biodetector based on reduced graphene oxide 115
Synthesis of functionalized [F-18]liposomes for preclinical PET imaging in Alzheimer's disease 115
Stability of Aβ (1-42) peptide fibrils as consequence of environmental modifications 113
Liposomes functionalized with GT1b ganglioside with high affinity for amyloid beta-peptide 113
Enhanced brain targeting of engineered solid lipid nanoparticles 111
Proteomics of plasma membrane microdomains 110
Lipid-based nanoparticles (NPs) with high binding affinity for amyloid-beta1-42 peptide modulate the barrier properties of a monolayer of endothelial cells 110
Implicazioni nutrizionali nella malattia di Alzheimer 109
A Novel Retro-Inverso Peptide Inhibitor Reduces Amyloid Deposition, Oxidation and Inflammation and Stimulates Neurogenesis in the APPswe/PS1 Delta E9 Mouse Model of Alzheimer's Disease 109
Glycolipid-protein interaction in the mechanism of signal transduction: studies with a photoactivable ganglioside analogue 108
Antibody-functionalized polymer nanoparticle leading to memory recovery in Alzheimer's disease-like transgenic mouse model 108
Nanoparticles for neuroimaging 107
Multi-functional liposomes prevent memory impairment and slow down brain B-amyloid deposition in a mouse model of Alzheimer’s disease. 106
Cellular uptake of coumarin-6 as a model drug loaded in solid lipid nanoparticles 104
Functionalization with curcumin-derivative and TAT peptide enhances the interaction with human brain capillary endothelial cells of nanoliposomes binding amyloid-beta peptide 104
Raman spectroscopy uncovers biochemical tissue-related features of extracellular vesicles from mesenchymal stromal cells 104
Totale 15896
Categoria #
all - tutte 33343
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 33343

Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2017/2018106 0000 00 00 000106
2018/20191904 54625261 63244 15790 123277321400
2019/20204073 472272274277 434484 632301 38321126370
2020/20212536 227153286288 204165 269153 23625896201
2021/20221838 98167176189 76175 142100 104169158284
2022/20234034 4491198338396 230562 90244 2876116910
Totale 19340