Distribuzione geografica
Continente #
NA - Nord America 18443
EU - Europa 5547
AS - Asia 1432
SA - Sud America 23
Continente sconosciuto - Info sul continente non disponibili 21
AF - Africa 20
OC - Oceania 8
Totale 25494
Nazione #
US - Stati Uniti d'America 18208
SE - Svezia 1261
DE - Germania 1081
IT - Italia 1073
CN - Cina 1055
UA - Ucraina 692
GB - Regno Unito 317
IE - Irlanda 283
CA - Canada 233
VN - Vietnam 159
RU - Federazione Russa 149
FI - Finlandia 141
AT - Austria 131
FR - Francia 126
TR - Turchia 95
BE - Belgio 91
DK - Danimarca 70
IN - India 56
NL - Olanda 51
JP - Giappone 23
EU - Europa 16
BG - Bulgaria 15
BR - Brasile 13
IR - Iran 13
ES - Italia 10
RO - Romania 10
NO - Norvegia 9
GR - Grecia 8
AU - Australia 7
KR - Corea 7
CH - Svizzera 6
MU - Mauritius 6
PL - Polonia 6
EG - Egitto 5
AR - Argentina 4
CL - Cile 4
CZ - Repubblica Ceca 4
PT - Portogallo 4
RE - Reunion 4
SG - Singapore 4
TH - Thailandia 4
A2 - ???statistics.table.value.countryCode.A2??? 3
IL - Israele 3
UZ - Uzbekistan 3
HK - Hong Kong 2
KZ - Kazakistan 2
MX - Messico 2
RS - Serbia 2
SC - Seychelles 2
TW - Taiwan 2
ZA - Sudafrica 2
A1 - ???statistics.table.value.countryCode.A1??? 1
AE - Emirati Arabi Uniti 1
AL - Albania 1
AM - Armenia 1
AP - ???statistics.table.value.countryCode.AP??? 1
BA - Bosnia-Erzegovina 1
BT - Bhutan 1
BY - Bielorussia 1
HU - Ungheria 1
ID - Indonesia 1
LT - Lituania 1
LU - Lussemburgo 1
LV - Lettonia 1
NG - Nigeria 1
NZ - Nuova Zelanda 1
PE - Perù 1
VE - Venezuela 1
Totale 25494
Città #
Ann Arbor 3634
Fairfield 2292
Woodbridge 2114
Houston 1638
Chandler 1252
Wilmington 1058
Frankfurt am Main 891
Ashburn 874
Seattle 833
Cambridge 798
Jacksonville 755
Dearborn 605
Princeton 492
Dublin 283
Milan 279
Lawrence 239
Altamura 224
Nanjing 223
San Diego 147
Beijing 130
Vienna 129
Lachine 124
Brussels 87
Dong Ket 80
Andover 79
Nanchang 77
Lissone 72
Shenyang 63
Toronto 62
Fuzhou 58
Guangzhou 56
Hebei 55
Jinan 48
Changsha 46
Tianjin 46
Boardman 43
Norwalk 41
Rome 35
Falls Church 34
Jiaxing 32
London 30
Ningbo 29
Philadelphia 28
Zhengzhou 26
Besana In Brianza 25
Fremont 25
Hangzhou 25
Ottawa 24
Redmond 24
Kocaeli 23
Kunming 23
Mountain View 23
Chicago 22
Huizen 20
Göttingen 17
Hefei 17
San Mateo 17
Shanghai 14
Edmonton 13
Grafing 13
Taizhou 13
Nürnberg 11
Bologna 10
Brugherio 10
Helsinki 10
Paris 10
Perugia 10
Leawood 9
Mariano Comense 9
Monza 9
Padova 9
Auburn Hills 8
University Park 8
Oslo 7
Phoenix 7
Plovdiv 7
Rho 7
Sacramento 7
Turin 7
Athens 6
Changchun 6
Chengdu 6
Gap 6
Haikou 6
Kiev 6
Sofia 6
Bari 5
Cairo 5
Daejeon 5
Duncan 5
Fürstenwalde 5
Hanover 5
Kirkland 5
Los Angeles 5
Merate 5
Montréal 5
Mumbai 5
San Francisco 5
Taiyuan 5
Wuhan 5
Totale 20746
Nome #
Prenatal Origin of Pediatric Leukemia: Lessons From Hematopoietic Development 338
NIPBL: a new player in myeloid cells differentiation 282
First evidence of a paediatric patient with Cornelia de Lange syndrome with acute lymphoblastic leukaemia 276
Clinical features and outcome of SIL/TAL1-positive t-cell acute lymphoblastic leukemia in children and adolescents: A 10-year experience of the AIEOP group 262
Immunogenotype changes prevail in relapses of young children with TEL-AML1-positive acute lymphoblastic leukemia and derive mainly from clonal selection 256
Phenotypical and Functional Characterization of Mesenchymal Stem Cells Derived From Patients Affected by Schwachman-Diamond Syndrome 255
Unravelling the cellular origin and clinical prognostic markers of infant B-cell acute lymphoblastic leukemia using genome-wide analysis 240
Predictive value of minimal residual disease in philadelphia-chromosome-positive acute lymphoblastic leukemia treated with imatinib in the European intergroup study of post-induction treatment of Philadelphia-chromosome-positive acute lymphoblastic leukemia, based on immunoglobulin/T-cell receptor and BCR/ABL1 methodologies 236
Hodgkin lymphoma in a patient with mosaic trisomy 18: First clinical observation 233
Activin A contributes to the definition of a pro-oncogenic bone marrow microenvironment in t(12;21) preleukemia 212
Preclinical Efficacy and Safety of CD19CAR Cytokine-Induced Killer Cells Transfected with Sleeping Beauty Transposon for the Treatment of Acute Lymphoblastic Leukemia 205
The histone deacetylase inhibitor givinostat (ITF2357) exhibits potent anti-tumor activity against CRLF2-rearranged BCP-ALL 203
Sleeping Beauty-engineered CAR T cells achieve anti-leukemic activity without severe toxicities 199
Antileukemic efficacy of BET inhibitor in a preclinical mouse model of MLL-AF4 + infant ALL 196
Pro-inflammatory cytokines favor the emergence of ETV6-RUNX1-positive pre-leukemic cells in a model of mesenchymal niche 191
Epigenetic silencing of BIM in glucocorticoid poor-responsive pediatric acute lymphoblastic leukemia, and its reversal by histone deacetylase inhibition 190
Drug-induced immunophenotypic modulation in childhood ALL: implications for minimal residual disease detection 189
A simple RNA target capture NGS strategy for fusion genes assessment in the diagnostics of pediatric B-cell acute lymphoblastic leukemia 183
Optimization of PCR-based minimal residual disease diagnostics for childhood acute lymphoblastic leukemia in a multi-center setting 182
IKZF1 plus defines a new minimal residual disease-dependent very-poor prognostic profile in pediatric b-cell precursor acute lymphoblastic leukemia 175
Development of a quantitative-PCR method for specific FLT3/ITD monitoring in acute myeloid leukemia 173
Standardisation and consensus guidelines for minimal residual disease assessment in Philadelphia-positive acute lymphoblastic leukemia (Ph + ALL) by real-time quantitative reverse transcriptase PCR of e1a2 BCR-ABL1 171
Minimal residual disease-directed risk stratification using real-time quantitative PCR analysis of immunoglobulin and T-cell receptor gene rearrangements in the international multicenter trial AIEOP-BFM ALL 2000 for childhood acute lymphoblastic leukemia 167
TNFRSF13C (BAFFR) positive blasts persist after early treatment and at relapse in childhood B-cell precursor acute lymphoblastic leukaemia 167
Cytoskeletal Regulatory Gene Expression and Migratory Properties of B Cell Progenitors are Affected by the ETV6-RUNX1 Rearrangement 166
CEQer: A Graphical Tool for Copy Number and Allelic Imbalance Detection from Whole-Exome Sequencing Data 165
Nucleophosmin mutations in childhood acute myelogenous leukemia with normal karyotype 162
Genetic evidence for lineage-related and differentiation stage-related contribution of somatic PTPN11 mutations to leukemogenesis in childhood acute leukemia 161
CyclinD1 Down-Regulation and Increased Apoptosis Are Common Features of Cohesinopathies 161
Modeling Cornelia de Lange syndrome in vitro and in vivo reveals a role for cohesin complex in neuronal survival and differentiation 161
Efficient detection of leukemia-related fusion transcripts by multiplex PCR applied on a microelectronic platform 160
Highly sensitive mutations detection in BCR-ABL positive leukemia prior and during imatinib treatment 160
Prospective molecular monitoring of BCR/ABL transcript in children with Ph+ acute lymphoblastic leukaemia unravels differences in treatment response 160
Good outcome for very high risk adult B-cell acute lymphoblastic leukaemia carrying genetic abnormalities t(4;11)(q21;q23) or t(9;22)(q34;q11), if promptly submitted to allogeneic transplantation, after obtaining a good molecular remission 160
Impact of IKZF1 deletions on IKZF1 expression and outcome in Philadelphia chromosome negative childhood BCP-ALL. Reply to "incidence and biological significance of IKZF1/Ikaros gene deletions in pediatric Philadelphia chromosome negative and Philadelphia chromosome positive B-cell precursor acute lymphoblastic leukemia". 159
Two siblings presenting with novel ADA2 variants, lymphoproliferation, persistence of large granular lymphocytes, and T-cell perturbations 159
Engineered T cells towards TNFRSF13C (BAFFR): a novel strategy to efficiently target B-cell acute lymphoblastic leukaemia 158
Absent B cells, agammaglobulinemia, and hypertrophic cardiomyopathy in folliculin-interacting protein 1 deficiency 158
Nodal monoclonal CD5-positive B-lymphocytosis and toxoplasma lymphadenitis: Another variant in the spectrum of infectious lymphadenitis in patients with chronic leukemia/small lymphocytic lymphoma 155
Somatically acquired JAK1 mutations in adult acute lymphoblastic leukemia 155
PAX5/TEL acts as a transcriptional repressor causing down-modulation of CD19, enhances migration to CXCL12, and confers survival advantage in pre-BI cells 153
The bone marrow niche in b-cell acute lymphoblastic leukemia: The role of microenvironment from pre-leukemia to overt leukemia 153
Targeting of hyperactivated mTOR signaling in high-risk acute lymphoblastic leukemia in a pre-clinical model 152
Characterization of children with FLT3-ITD acute myeloid leukemia: A report from the AIEOP AML-2002 study group 152
Prognostic value of rare IKZF1 deletion in childhood B-cell precursor acute lymphoblastic leukemia: An international collaborative study 150
Defining the correct role of minimal residual disease tests in the management of acute lymphoblastic leukaemia 149
Human MLL/KMT2A gene exhibits a second breakpoint cluster region for recurrent MLL–USP2 fusions 149
Clinico-biologic features of 5202 acute lymphoblastic leukemia patients enrolled in the Italian AIEOP and GIMEMA Protocols and stratified in age-cohorts 145
Suppressors and activators of JAK-STAT signaling at diagnosis and relapse of acute lymphoblastic leukemia in Down syndrome 145
PAX5/ETV6 alters the gene expression profile of precursor B cells with opposite dominant effect on endogenous PAX5 143
The sensitivity of acute lymphoblastic leukemia cells carrying the t(12;21) translocation to campath-1H-mediated cell lysis 142
Quiescent leukaemic cells account for minimal residual disease in childhood lymphoblastic leukaemia 142
Mesenchymal stem cells from Shwachman-Diamond syndrome patients display normal functions and do not contribute to hematological defects 142
Dexamethasone vs prednisone in induction treatment of pediatric ALL: results of the randomized trial AIEOP-BFM ALL 2000 142
Rings and bricks: Expression of cohesin components is dynamic during development and adult life 142
A novel homozygous disruptive PRF1 variant (K285Sfs*4) causes very early-onset of familial hemophagocytic lymphohystiocytosis type 2 142
Minimal residual disease before and after transplantation for childhood acute lymphoblastic leukaemia: is there any room for intervention? 142
Detection of PICALM-MLLT10 (CALM-AF10) and outcome in children with T-lineage acute lymphoblastic leukemia 141
LCK over-expression drives STAT5 oncogenic signaling in PAX5 translocated BCP-ALL patients 141
Quantitative assessment of minimal residual disease in acute myeloid leukemia carrying nucleophosmin (NPM1) gene mutations 140
Molecular response to treatment redefines all prognostic factors in children and adolescents with B-cell precursor acute lymphoblastic leukemia: results in 3184 patients of the AIEOP-BFM ALL 2000 study 139
What is the relevance of Ikaros gene deletions as prognostic marker in pediatric Philadelphia negative B-cell precursor acute lymphoblastic leukemia? 137
IKZF1 Deletions with COBL Breakpoints Are Not Driven by RAG-Mediated Recombination Events in Acute Lymphoblastic Leukemia 137
DNA copy-number abnormalities do not occur in infant ALL with t(4;11)/MLL-AF4 136
TEL/ARG induces cytoskeletal abnormalities in 293T cells 135
Standardization of WT1 mRNA quantitation for minimal residual disease monitoring in childhood AML and implications of WT1 gene mutations: a European multicenter study 135
Clinical Implications of Minimal Residual Disease Detection in Infants With KMT2A-Rearranged Acute Lymphoblastic Leukemia Treated on the Interfant-06 Protocol 135
Clonal variegation and dynamic competition of leukemia-initiating cells in infant acute lymphoblastic leukemia with MLL rearrangement 133
Novel Chimeric Transcripts Involving PAX5 in B-Cell Precursor ALL 131
Phosphoproteomic analysis reveals hyperactivation of mTOR/STAT3 and LCK/Calcineurin axes in pediatric early T-cell precursor ALL 131
High incidence and unique features of antigen receptor gene rearrangements in TEL-AML1-positive leukemias 129
Fine Tuning of Surface CRLF2 Expression and Its Associated Signalling Profile in Childhood B Cell Precursor Acute Lymphoblastic Leukemia 129
DNA variants in DHFR gene and response to treatment in children with childhood B ALL: Revisited in AIEOP-BFM protocol 129
Early T-cell precursor acute lymphoblastic leukaemia in children treated in AIEOP centres with AIEOP-BFM protocols: A retrospective analysis 129
Implementation of array based whole-genome high-resolution technologies confirms the absence of secondary copy-number alterations in MLL-AF4-positive infant ALL patients 128
Mutations of JAK2 in acute lymphoblastic leukaemias associated with Down's syndrome 127
In Infant ALL with t(4;11)/MLL-AF4 Multiple and Phenotypically Distinct CD19+ BM Subsets Initiate Leukemia in NOD/SCID Mice 126
CRLF2 over-expression is a poor prognostic marker in children with high risk T-cell acute lymphoblastic leukemia 126
PTEN opposes negative selection and enables oncogenic transformation of pre-B cells 125
Predictive factors of relapse and survival in childhood acute myeloid leukemia: Role of minimal residual disease 124
Poor Prognosis for IKZF1 Intra-Gene Deletions in Pediatric Ph– B-Cell Precursor Acute Lymphoblastic Leukemia 123
Acute myeloid leukemia in Baraitser–Winter cerebrofrontofacial syndrome 123
The presence of mutated and deleted PTEN is associated with an increased risk of relapse in childhood T cell acute lymphoblastic leukaemia treated with AIEOP-BFM ALL protocols 123
Somatic PTPN11 mutations in childhood acute myeloid leukaemia 122
The silent mutational landscape of infant MLL-AF4 pro-B acute lymphoblastic leukemia 122
Poor prognosis for P2RY8-CRLF2 fusion but not for CRLF2 over-expression in children with intermediate risk B-cell precursor acute lymphoblastic leukemia 120
Loss of CBL E3-ligase activity in B-lineage childhood acute lymphoblastic leukaemia 120
High expression of miR-125b-2 and SNORD116 noncoding RNA clusters characterize ERG-related B cell precursor acute lymphoblastic leukemia 120
Germ-Line TP53 Mutation in an Adolescent With CMML/Atypical CML and Familiar Cancer Predisposition 119
Randomized post-induction and delayed intensification therapy in high-risk pediatric acute lymphoblastic leukemia: long-term results of the international AIEOP-BFM ALL 2000 trial 118
SSBP2-CSF1R is a Recurrent Fusion in B-lineage Acute Lymphoblastic Leukaemia with Diverse Genetic Presentation and Variable Outcome 118
Genomic analysis of different clonal evolution in a twin pair with t(12;21) positive acute lymphoblastic leukemia sharing the same prenatal clone 117
T-cell lymphoblastic lymphoma shows differences and similarities with T-cell acute lymphoblastic leukemia by genomic and gene expression analyses 117
SRC/ABL inhibition disrupts CRLF2-driven signaling to induce cell death in B-cell acute lymphoblastic leukemia 117
High EVI1 Expression due to NRIP1/EVI1 Fusion in Therapy-related Acute Myeloid Leukemia: Description of the First Pediatric Case 117
Recurrent genetic fusions redefine MLL germ line acute lymphoblastic leukemia in infants 117
Genomic imbalances are confined to non-proliferating cells in paediatric patients with acute myeloid leukaemia and a normal or incomplete karyotype 116
Low prevalence of IDH1 gene mutation in childhood AML in Italy 116
Mechanisms of resistance to imatinib in chronic myeloid leukemia (CML) patients in chronic phase (CP) who achieved durable complete cytogenetic responses (CCR) 116
Novel clinical trials for pediatric leukemias: lessons learned from genomic analyses 116
Totale 15646
Categoria #
all - tutte 51708
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 51708

Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2017/201828 0000 00 00 00028
2018/20192630 34793723 46203 11399 93349743811
2019/20206135 727350408607 651776 796450 553343317157
2020/20215491 222341432474 446436 816678 399494350403
2021/20223278 232342419237 256271 123177 208230227556
2022/20235276 6631625374426 276792 105324 3767022817
Totale 26578