LEONI, VALERIO
 Distribuzione geografica
Continente #
NA - Nord America 10.892
AS - Asia 7.956
EU - Europa 5.008
SA - Sud America 1.415
AF - Africa 193
OC - Oceania 23
Continente sconosciuto - Info sul continente non disponibili 4
Totale 25.491
Nazione #
US - Stati Uniti d'America 10.337
SG - Singapore 2.794
CN - Cina 1.543
IT - Italia 1.454
VN - Vietnam 1.227
HK - Hong Kong 1.203
BR - Brasile 1.092
RU - Federazione Russa 886
DE - Germania 554
IE - Irlanda 495
CA - Canada 455
SE - Svezia 414
FR - Francia 258
GB - Regno Unito 238
BD - Bangladesh 230
IN - India 189
ID - Indonesia 144
UA - Ucraina 138
AR - Argentina 136
FI - Finlandia 128
KR - Corea 113
JP - Giappone 89
IQ - Iraq 81
ZA - Sudafrica 72
NL - Olanda 70
AT - Austria 65
PL - Polonia 65
TR - Turchia 65
ES - Italia 64
EC - Ecuador 63
MX - Messico 53
CH - Svizzera 44
CO - Colombia 38
PK - Pakistan 35
PH - Filippine 31
SA - Arabia Saudita 30
UZ - Uzbekistan 28
CL - Cile 26
MA - Marocco 22
MD - Moldavia 20
AU - Australia 19
JO - Giordania 19
KE - Kenya 19
VE - Venezuela 19
DK - Danimarca 17
RO - Romania 16
TN - Tunisia 15
AE - Emirati Arabi Uniti 13
EG - Egitto 13
MY - Malesia 13
PY - Paraguay 13
AZ - Azerbaigian 11
CZ - Repubblica Ceca 11
ET - Etiopia 11
LB - Libano 11
PE - Perù 11
DZ - Algeria 10
IL - Israele 10
JM - Giamaica 10
LT - Lituania 9
NP - Nepal 9
AL - Albania 8
GR - Grecia 8
OM - Oman 8
PT - Portogallo 8
UY - Uruguay 8
BO - Bolivia 7
CR - Costa Rica 7
KZ - Kazakistan 7
NG - Nigeria 7
BG - Bulgaria 6
GT - Guatemala 6
IR - Iran 6
NO - Norvegia 6
BE - Belgio 5
BY - Bielorussia 5
SN - Senegal 5
TT - Trinidad e Tobago 5
TW - Taiwan 5
HR - Croazia 4
KG - Kirghizistan 4
KW - Kuwait 4
NI - Nicaragua 4
PS - Palestinian Territory 4
SC - Seychelles 4
TH - Thailandia 4
BA - Bosnia-Erzegovina 3
BH - Bahrain 3
CY - Cipro 3
DO - Repubblica Dominicana 3
EU - Europa 3
GH - Ghana 3
HN - Honduras 3
NZ - Nuova Zelanda 3
PA - Panama 3
QA - Qatar 3
RS - Serbia 3
SV - El Salvador 3
SY - Repubblica araba siriana 3
AM - Armenia 2
Totale 25.454
Città #
Singapore 1.549
Hong Kong 1.175
Ann Arbor 1.140
Ashburn 989
Fairfield 972
San Jose 580
Dublin 479
Milan 479
Wilmington 472
Woodbridge 432
Ho Chi Minh City 396
Seattle 386
Houston 380
Dallas 365
Toronto 356
Frankfurt am Main 346
Cambridge 338
Santa Clara 283
New York 271
Hanoi 268
Los Angeles 238
Chicago 228
Hefei 225
Chandler 194
Princeton 192
The Dalles 187
Beijing 178
Council Bluffs 145
Dearborn 143
Moscow 129
São Paulo 126
Lauterbourg 120
Jakarta 104
Rome 103
Seoul 99
Altamura 93
Lawrence 93
San Diego 88
Shanghai 84
Helsinki 80
Jacksonville 77
Buffalo 74
Boardman 58
Nanjing 56
Da Nang 54
Munich 49
Tokyo 47
Orem 45
Haiphong 44
London 44
Montreal 44
Nuremberg 44
Warsaw 41
Vienna 40
Baghdad 37
Guangzhou 36
Monza 35
Andover 34
Rio de Janeiro 34
Columbus 28
Denver 28
Lappeenranta 28
Zurich 28
Atlanta 27
Guayaquil 27
Tashkent 27
Biên Hòa 26
Chennai 26
Brooklyn 25
Johannesburg 25
Paris 25
Poplar 25
Amsterdam 24
Curitiba 23
Phoenix 23
Washington 23
Belo Horizonte 22
Salt Lake City 22
Shenyang 22
Stockholm 22
Chisinau 20
Kent 20
Amman 19
Ha Long 19
Hangzhou 19
Nanchang 19
Turku 19
Brasília 18
Changsha 18
Mumbai 18
Quito 17
San Francisco 17
Tampa 17
Tianjin 17
Ankara 16
Boston 16
Chengdu 16
Desio 16
Florence 16
Nairobi 16
Totale 16.277
Nome #
CRISPR/Cas9-mediated knockout of Abcd1 and Abcd2 genes in BV-2 cells: novel microglial models for X-linked Adrenoleukodystrophy 536
A microglial cell model for acyl-CoA oxidase 1 deficiency 420
DNA damage in circulating hematopoietic progenitor stem cells as promising biological sensor of frailty 410
C-reactive protein modifies lipoprotein(a)-related risk for coronary heart disease: the BiomarCaRE project 399
Surfactant protein D (SP-D) as a biomarker of SARS-CoV-2 infection 389
DNA damage and reactive oxygen species as promising biological indicators of friality 359
4-IPP, a selective MIF inhibitor, causes mitotic catastrophe in thyroid carcinomas 338
Baseline characteristics of COVID-19 Italian patients admitted to Desio Hospital, Lombardy: a retrospective study 334
The cholesterol metabolite 27-hydroxycholesterol inhibits SARS-CoV-2 and is markedly decreased in COVID-19 patients 329
Bacterial and fungal colonization of the respiratory tract in COVID-19 patients should not be neglected 310
Monoclonal free light chain detection and quantification: Performances and limits of available laboratory assays 281
Induction of the intestinal membrane transporters ABCA1 and ABCG8 by 27-hydroxycholesterol through a redox mechanism 269
Unraveling the complexity of anti-doping analysis: reassessing meldonium detection and doping verdicts in a case study 268
Impairment of Renal and Hematopoietic Stem/Progenitor Cell Compartments in Frailty Syndrome: Link with Oxidative Stress, Plasma Cytokine Profiles and Nuclear DNA Damage 260
Impact of Lipoprotein(a) Level on Low-Density Lipoprotein Cholesterol– or Apolipoprotein B–Related Risk of Coronary Heart Disease 259
Prevalence and species distribution of microorganisms isolated among non-pregnant women affected by vulvovaginal candidiasis: A retrospective study over a 20 year-period 257
Identification of a mechanism promoting mitochondrial sterol accumulation during myocardial ischemia–reperfusion: role of TSPO and STAR 257
Spheroplasts, poorly known but clinically relevant particles of urinary sediment 256
Diagnostic use of cerebral and extracerebral oxysterols 254
On the fluxes of side-chain oxidized oxysterols across blood-brain and blood-CSF barriers and origin of these steroids in CSF (Review) 245
Oxysterols present in Alzheimer's disease brain induce synaptotoxicity by activating astrocytes: A major role for lipocalin-2 242
Antimicrobial Resistance Trends of Escherichia coli Isolates from Outpatient and Inpatient Urinary Infections over a 20-Year Period 242
Antibody Response against SARS-CoV-2 after mRNA Vaccine in a Cohort of Hospital Healthy Workers Followed for 17 Months 240
Antimicrobial Resistance Patterns of Enterobacter cloacae and Klebsiella aerogenes Strains Isolated from Clinical Specimens: A Twenty-Year Surveillance Study 237
SREBP2 gene therapy targeting striatal astrocytes ameliorates Huntington's disease phenotypes 230
Roles, Functions, and Pathological Implications of Exosomes in the Central Nervous System 229
Urinary Sediment Interpretation: The Clinical Role of Spheroplasts 227
Increased production of 27-hydroxycholesterol in human colorectal cancer advanced stage: Possible contribution to cancer cell survival and infiltration 227
Effect of industrial processing and storage procedures on oxysterols in milk and milk products 227
Striatal infusion of cholesterol promotes dose‐dependent behavioral benefits and exerts disease‐modifying effects in Huntington's disease mice 225
Cardiovascular Structural and Functional Parameters in Idiopathic Pulmonary Fibrosis at Disease Diagnosis 222
Biological conditions related to friality and their effects on adult renal stem cells cultured as nephrospheres 221
Purple corn extract induces long-lasting reprogramming and M2 phenotypic switch of adipose tissue macrophages in obese mice 215
Oxysterols and Alzheimer's disease 215
Oxysterols as markers of neurological disease--a review 210
Alteration of Lipid Metabolism in Patients with IPF and Its Association with Disease Severity and Prognosis: A Case–Control Study 205
Octadecaneuropeptide (ODN) induces N2a cells differentiation through a PKA/PLC/PKC/MEK/ERK-dependent pathway: Incidence on peroxisome, mitochondria, and lipid profiles 203
Dimethyl fumarate and monomethyl fumarate attenuate oxidative stress and mitochondrial alterations leading to oxiapoptophagy in 158N murine oligodendrocytes treated with 7β-hydroxycholesterol 202
First international descriptive and interventional survey for cholesterol and non-cholesterol sterol determination by gas- and liquid-chromatography–Urgent need for harmonisation of analytical methods 202
Antibody Response after 3-Dose Booster against SARS-CoV-2 mRNA Vaccine in Kidney Transplant Recipients 201
Altered Brain Cholesterol Machinery in a Down Syndrome Mouse Model: A Possible Common Feature with Alzheimer’s Disease 200
Sleep quality and cerebrospinal fluid oxysterols in degenerative dementias: correlations and possible biomedical implications 197
Biotin attenuation of oxidative stress, mitochondrial dysfunction, lipid metabolism alteration and 7β-hydroxycholesterol-induced cell death in 158N murine oligodendrocytes 196
Side chain oxidized oxysterols in cerebrospinal fluid and the integrity of blood-brain and blood-cerebrospinal fluid barriers 194
Oxysterols and neurodegenerative diseases 193
MIF/CD74 axis is a target for novel therapies in colon carcinomatosis 193
Levels of ApoE in cerebrospinal fluid are correlated with Tau and 24S-hydroxycholesterol in patients with cognitive disorders 192
The Diagnostic Use of the Plasma Quantification of 24S-Hydroxycholesterol and Other Oxysterols in Neurodegenerative Disease 190
Modulation of cell proteome by 25-hydroxycholesterol and 27-hydroxycholesterol: A link between cholesterol metabolism and antiviral defense 190
Involvement of 27-Hydroxycholesterol in Mitotane Action on Adrenocortical Carcinoma 189
Plasma levels of 24S-hydroxycholesterol reflect brain volumes in patients without objective cognitive impairment but not in those with Alzheimer's disease 187
Antiviral oxysterols are present in human milk at diverse stages of lactation 187
Oxysterols as biomarkers in neurodegenerative diseases 186
Elevated 24-hydroxycholesterol levels counteract okadaic acid-induced tau hyperphosphorylation and neuronal morphology impairment 183
Oxysterols in the development of diabetes and cardiovascular diseases 182
Identification of SARS-CoV-2 positivity using machine learning methods on blood count data: External validation of state-of-the-art models. [Identificazione di positività al SARS-CoV-2 attraverso metodi di Machine Learning sui dati dell'esame emocromocitometrico: Validazione esterna di modelli allo stato dell'arte] 182
The effect of apolipoprotein E (ApoE) genotype on biomarkers of amyloidogenesis, tau pathology and neurodegeneration in Alzheimer's disease 181
Changes in human plasma levels of the brain specific oxysterol 24S-hydroxycholesterol during progression of multiple sclerosis 180
Genetic connections between neurological disorders and cholesterol metabolism 180
Mitochondrial dysfunctions in 7-ketocholesterol-treated 158N oligodendrocytes without or with α-tocopherol: Impacts on the cellular profil of tricarboxylic cycle-associated organic acids, long chain saturated and unsaturated fatty acids, oxysterols, cholesterol and cholesterol precursors 180
Individual Comparison of Cholesterol Metabolism in Normal and Tumour Areas in Radical Prostatectomy Specimens from Patients with Prostate Cancer: Results of the CHOMECAP Study 180
Inhibition of herpes simplex-1 virus replication by 25-hydroxycholesterol and 27-hydroxycholesterol 179
Cholesterol defect is marked across multiple rodent models of Huntington's disease and is manifest in astrocytes 176
Sex‐difference in flux of 27‐hydroxycholesterol in the brain 176
Hsp22 overexpression induces myocardial hypertrophy, senescence and reduced life span through enhanced oxidative stress 175
Impact of elective surgery on tumor necrosis factor-α, interleukin-6 and quality of life in uncomplicated diverticular disease 174
Biological conditions related to frailty influence the behavior of renal stem/progenitor cells grown as nephrospheres 173
Enhanced molecular release from elderly bone samples using collagenase I: insights into fatty acid metabolism alterations 173
Cholesterol-loaded nanoparticles ameliorate synaptic and cognitive function in Huntington's disease mice 173
Cholesterol biosynthesis pathway is disturbed in YAC128 mice and is modulated by huntingtin mutation 172
Association between Diet Quality and Index of Non-Alcoholic Steatohepatitis in a Large Population of People with Type 2 Diabetes: Data from the TOSCA.IT Study 170
Metabolic consequences of mitochondrial coenzyme A deficiency in patients with PANK2 mutations 170
Insights into kinetics, release, and behavioral effects of brain-targeted hybrid nanoparticles for cholesterol delivery in Huntington's disease 169
Familial Alzheimer's disease associated with heterozygous NPC1 mutation 168
NAD(+)-Dependent Activation of Sirt1 Corrects the Phenotype in a Mouse Model of Mitochondrial Disease 168
24S-hydroxycholesterol in plasma: A marker of cholesterol turnover in neurodegenerative diseases 167
Plasma 24S-hydroxycholesterol and caudate MRI in pre-manifest and early Huntington's disease 167
Oxysterols and Parkinson's disease: evidence that levels of 24S-hydroxycholesterol in cerebrospinal fluid correlates with the duration of the disease 167
Trend of 25-hydroxycholesterol and 27-hydroxycholesterol plasma levels in patients affected by active chronic hepatitis B virus infection and inactive carriers 167
Biological variation of Serum Amyloid A in healthy subjects 166
Antibody response after two doses of the SARS-CoV-2 Comirnaty vaccine in a Covid-19 positive and Covid-19 negative Italian healthcare workers cohort 166
Upregulation of brain renin angiotensin system by 27-hydroxycholesterol in Alzheimer's disease 165
Levels of 7-oxocholesterol in cerebrospinal fluid are more than one thousand times lower than reported in multiple sclerosis 164
Oxysterols and multiple sclerosis: Physiopathology, evolutive biomarkers and therapeutic strategy 163
Progressive dysfunction of the cholesterol biosynthesis pathway in the R6/2 mouse model of Huntington's disease 161
Early and brain region-specific decrease of de novo cholesterol biosynthesis in Huntington's disease: A cross-validation study in Q175 knock-in mice 161
Liver X receptors constrain tumor development and metastasis dissemination in PTEN-deficient prostate cancer 160
International descriptive and interventional survey for oxycholesterol determination by gas- and liquid-chromatographic methods 157
Induction of peroxisomal changes in oligodendrocytes treated with 7-ketocholesterol: Attenuation by α-tocopherol 157
Are the CSF levels of 24S-hydroxycholesterol a sensitive biomarker for mild cognitive impairment? 156
Whole body cholesterol metabolism is impaired in Huntington's disease 156
Therapeutic Applications of Oxysterols and Derivatives in Age-Related Diseases, Infectious and Inflammatory Diseases, and Cancers 155
The impairment of cholesterol metabolism in Huntington disease 155
Evidence for sex difference in the CSF/plasma albumin ratio in ~20 000 patients and 335 healthy volunteers 155
Elective Laparoscopic Sigmoidectomy Reduces IL-6 Serum Levels in Uncomplicated Recurrent Diverticulitis 155
Glucose accelerates copper- and ceruloplasmin-induced oxidation of low-density lipoprotein and whole serum 154
High levels of 15-oxygenated steroids in circulation of patients with multiple sclerosis: Fact or fi ction? 151
Intestinal permeability and Ménière's disease 151
Lipid droplets dependent or independent cytoprotective activities of unsaturated fatty acids, Lorenzo's oil and sulfo-N-succinimidyl oleate on 7-ketocholesterol-induced oxidative stress, organelle dysfunction and cell death on 158N and ARPE-19 cells: Cell targets and benefits of sulfo-N-succinimidyl oleate 151
Study of cholesterol metabolism in Huntington's disease 150
Totale 21.187
Categoria #
all - tutte 91.929
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 91.929


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.224 137 128 168 93 83 93 70 73 47 79 93 160
2022/20231.701 224 470 153 76 103 274 69 65 116 41 56 54
2023/20241.507 48 50 62 55 201 307 283 56 209 28 41 167
2024/20255.104 268 636 265 200 353 191 375 127 568 770 511 840
2025/202611.747 1.088 1.019 1.080 1.375 1.205 522 1.557 558 923 856 811 753
2026/202721 21 0 0 0 0 0 0 0 0 0 0 0
Totale 26.265