LEONI, VALERIO
 Distribuzione geografica
Continente #
NA - Nord America 12.241
AS - Asia 8.019
EU - Europa 5.169
SA - Sud America 1.444
Continente sconosciuto - Info sul continente non disponibili 782
AF - Africa 196
OC - Oceania 25
Totale 27.876
Nazione #
US - Stati Uniti d'America 11.629
SG - Singapore 2.807
IT - Italia 1.570
CN - Cina 1.553
VN - Vietnam 1.228
HK - Hong Kong 1.207
BR - Brasile 1.100
RU - Federazione Russa 886
DE - Germania 556
IE - Irlanda 495
CA - Canada 483
SE - Svezia 432
FR - Francia 260
GB - Regno Unito 250
BD - Bangladesh 242
IN - India 191
ID - Indonesia 145
AR - Argentina 139
UA - Ucraina 139
FI - Finlandia 131
KR - Corea 115
JP - Giappone 92
IQ - Iraq 81
NL - Olanda 72
ZA - Sudafrica 72
TR - Turchia 67
EC - Ecuador 66
AT - Austria 65
PL - Polonia 65
ES - Italia 64
MX - Messico 53
CO - Colombia 48
CH - Svizzera 44
PK - Pakistan 35
PH - Filippine 34
SA - Arabia Saudita 31
UZ - Uzbekistan 28
CL - Cile 26
MA - Marocco 22
AU - Australia 21
VE - Venezuela 21
MD - Moldavia 20
JO - Giordania 19
KE - Kenya 19
DK - Danimarca 17
JM - Giamaica 16
RO - Romania 16
CR - Costa Rica 15
MY - Malesia 15
TN - Tunisia 15
AE - Emirati Arabi Uniti 14
EG - Egitto 14
PY - Paraguay 13
CZ - Repubblica Ceca 12
AZ - Azerbaigian 11
ET - Etiopia 11
LB - Libano 11
PE - Perù 11
DZ - Algeria 10
IL - Israele 10
NP - Nepal 10
UY - Uruguay 10
LT - Lituania 9
TT - Trinidad e Tobago 9
AL - Albania 8
BO - Bolivia 8
GR - Grecia 8
KZ - Kazakistan 8
OM - Oman 8
PT - Portogallo 8
NG - Nigeria 7
BE - Belgio 6
BG - Bulgaria 6
GT - Guatemala 6
IR - Iran 6
NO - Norvegia 6
TW - Taiwan 6
BY - Bielorussia 5
HN - Honduras 5
NI - Nicaragua 5
RS - Serbia 5
SN - Senegal 5
BH - Bahrain 4
DO - Repubblica Dominicana 4
HR - Croazia 4
KG - Kirghizistan 4
KW - Kuwait 4
PS - Palestinian Territory 4
SC - Seychelles 4
SV - El Salvador 4
TH - Thailandia 4
BA - Bosnia-Erzegovina 3
BB - Barbados 3
CY - Cipro 3
EU - Europa 3
GH - Ghana 3
LY - Libia 3
NZ - Nuova Zelanda 3
PA - Panama 3
QA - Qatar 3
Totale 27.051
Città #
Singapore 1.553
Ashburn 1.177
Hong Kong 1.177
Ann Arbor 1.140
Fairfield 972
San Jose 758
Milan 505
Dublin 479
Wilmington 472
Woodbridge 433
Houston 398
Ho Chi Minh City 396
Seattle 392
Dallas 379
Toronto 357
Frankfurt am Main 346
Cambridge 339
Santa Clara 316
Council Bluffs 292
New York 284
Hanoi 268
Los Angeles 250
Chicago 239
Hefei 225
Princeton 196
Chandler 194
The Dalles 189
Beijing 182
Dearborn 143
Moscow 129
São Paulo 126
Lauterbourg 120
Rome 115
Jakarta 104
Seoul 99
Altamura 93
Lawrence 93
San Diego 93
Columbus 89
Shanghai 87
Helsinki 82
Jacksonville 80
Buffalo 75
Boardman 60
Nanjing 56
Da Nang 54
Munich 49
Tokyo 48
Montreal 47
Orem 47
London 46
Phoenix 46
Nuremberg 45
Haiphong 44
Warsaw 41
Vienna 40
Baghdad 37
Atlanta 36
Guangzhou 36
Monza 35
Rio de Janeiro 35
Andover 34
Brooklyn 33
Denver 30
Guayaquil 29
Chennai 28
Lappeenranta 28
Washington 28
Zurich 28
Tashkent 27
Biên Hòa 26
Paris 26
Amsterdam 25
Johannesburg 25
Poplar 25
Curitiba 24
San Francisco 23
Belo Horizonte 22
Kent 22
Salt Lake City 22
Shenyang 22
Stockholm 22
Boston 21
Chisinau 20
Turin 20
Amman 19
Brasília 19
Ha Long 19
Hangzhou 19
Nanchang 19
Tampa 19
Turku 19
Bologna 18
Changsha 18
Mumbai 18
Quito 18
Florence 17
Medellín 17
Tianjin 17
Ankara 16
Totale 17.120
Nome #
CRISPR/Cas9-mediated knockout of Abcd1 and Abcd2 genes in BV-2 cells: novel microglial models for X-linked Adrenoleukodystrophy 553
A microglial cell model for acyl-CoA oxidase 1 deficiency 434
DNA damage in circulating hematopoietic progenitor stem cells as promising biological sensor of frailty 425
C-reactive protein modifies lipoprotein(a)-related risk for coronary heart disease: the BiomarCaRE project 413
Surfactant protein D (SP-D) as a biomarker of SARS-CoV-2 infection 400
DNA damage and reactive oxygen species as promising biological indicators of friality 369
4-IPP, a selective MIF inhibitor, causes mitotic catastrophe in thyroid carcinomas 350
Baseline characteristics of COVID-19 Italian patients admitted to Desio Hospital, Lombardy: a retrospective study 345
The cholesterol metabolite 27-hydroxycholesterol inhibits SARS-CoV-2 and is markedly decreased in COVID-19 patients 338
Bacterial and fungal colonization of the respiratory tract in COVID-19 patients should not be neglected 318
Monoclonal free light chain detection and quantification: Performances and limits of available laboratory assays 294
Unraveling the complexity of anti-doping analysis: reassessing meldonium detection and doping verdicts in a case study 291
Induction of the intestinal membrane transporters ABCA1 and ABCG8 by 27-hydroxycholesterol through a redox mechanism 280
Identification of a mechanism promoting mitochondrial sterol accumulation during myocardial ischemia–reperfusion: role of TSPO and STAR 279
Impairment of Renal and Hematopoietic Stem/Progenitor Cell Compartments in Frailty Syndrome: Link with Oxidative Stress, Plasma Cytokine Profiles and Nuclear DNA Damage 277
Impact of Lipoprotein(a) Level on Low-Density Lipoprotein Cholesterol– or Apolipoprotein B–Related Risk of Coronary Heart Disease 276
Antimicrobial Resistance Patterns of Enterobacter cloacae and Klebsiella aerogenes Strains Isolated from Clinical Specimens: A Twenty-Year Surveillance Study 271
Prevalence and species distribution of microorganisms isolated among non-pregnant women affected by vulvovaginal candidiasis: A retrospective study over a 20 year-period 270
Spheroplasts, poorly known but clinically relevant particles of urinary sediment 267
Diagnostic use of cerebral and extracerebral oxysterols 263
Roles, Functions, and Pathological Implications of Exosomes in the Central Nervous System 261
Antibody Response against SARS-CoV-2 after mRNA Vaccine in a Cohort of Hospital Healthy Workers Followed for 17 Months 255
On the fluxes of side-chain oxidized oxysterols across blood-brain and blood-CSF barriers and origin of these steroids in CSF (Review) 253
Antimicrobial Resistance Trends of Escherichia coli Isolates from Outpatient and Inpatient Urinary Infections over a 20-Year Period 252
Urinary Sediment Interpretation: The Clinical Role of Spheroplasts 247
Oxysterols present in Alzheimer's disease brain induce synaptotoxicity by activating astrocytes: A major role for lipocalin-2 247
Cardiovascular Structural and Functional Parameters in Idiopathic Pulmonary Fibrosis at Disease Diagnosis 242
Effect of industrial processing and storage procedures on oxysterols in milk and milk products 242
SREBP2 gene therapy targeting striatal astrocytes ameliorates Huntington's disease phenotypes 239
Biological conditions related to friality and their effects on adult renal stem cells cultured as nephrospheres 235
Alteration of Lipid Metabolism in Patients with IPF and Its Association with Disease Severity and Prognosis: A Case–Control Study 235
Striatal infusion of cholesterol promotes dose‐dependent behavioral benefits and exerts disease‐modifying effects in Huntington's disease mice 235
Increased production of 27-hydroxycholesterol in human colorectal cancer advanced stage: Possible contribution to cancer cell survival and infiltration 233
The Diagnostic Use of the Plasma Quantification of 24S-Hydroxycholesterol and Other Oxysterols in Neurodegenerative Disease 225
Oxysterols and Alzheimer's disease 222
Elevated 24-hydroxycholesterol levels counteract okadaic acid-induced tau hyperphosphorylation and neuronal morphology impairment 220
Purple corn extract induces long-lasting reprogramming and M2 phenotypic switch of adipose tissue macrophages in obese mice 219
Impact of elective surgery on tumor necrosis factor-α, interleukin-6 and quality of life in uncomplicated diverticular disease 217
Oxysterols as markers of neurological disease--a review 217
Antibody Response after 3-Dose Booster against SARS-CoV-2 mRNA Vaccine in Kidney Transplant Recipients 216
Altered Brain Cholesterol Machinery in a Down Syndrome Mouse Model: A Possible Common Feature with Alzheimer’s Disease 216
Sleep quality and cerebrospinal fluid oxysterols in degenerative dementias: correlations and possible biomedical implications 212
First international descriptive and interventional survey for cholesterol and non-cholesterol sterol determination by gas- and liquid-chromatography–Urgent need for harmonisation of analytical methods 211
Dimethyl fumarate and monomethyl fumarate attenuate oxidative stress and mitochondrial alterations leading to oxiapoptophagy in 158N murine oligodendrocytes treated with 7β-hydroxycholesterol 210
Octadecaneuropeptide (ODN) induces N2a cells differentiation through a PKA/PLC/PKC/MEK/ERK-dependent pathway: Incidence on peroxisome, mitochondria, and lipid profiles 210
MIF/CD74 axis is a target for novel therapies in colon carcinomatosis 202
Biotin attenuation of oxidative stress, mitochondrial dysfunction, lipid metabolism alteration and 7β-hydroxycholesterol-induced cell death in 158N murine oligodendrocytes 201
Oxysterols in the development of diabetes and cardiovascular diseases 199
Oxysterols and neurodegenerative diseases 199
Levels of ApoE in cerebrospinal fluid are correlated with Tau and 24S-hydroxycholesterol in patients with cognitive disorders 198
Side chain oxidized oxysterols in cerebrospinal fluid and the integrity of blood-brain and blood-cerebrospinal fluid barriers 197
Identification of SARS-CoV-2 positivity using machine learning methods on blood count data: External validation of state-of-the-art models. [Identificazione di positività al SARS-CoV-2 attraverso metodi di Machine Learning sui dati dell'esame emocromocitometrico: Validazione esterna di modelli allo stato dell'arte] 197
Involvement of 27-Hydroxycholesterol in Mitotane Action on Adrenocortical Carcinoma 196
Oxysterols as biomarkers in neurodegenerative diseases 194
The effect of apolipoprotein E (ApoE) genotype on biomarkers of amyloidogenesis, tau pathology and neurodegeneration in Alzheimer's disease 194
Association between Diet Quality and Index of Non-Alcoholic Steatohepatitis in a Large Population of People with Type 2 Diabetes: Data from the TOSCA.IT Study 193
Modulation of cell proteome by 25-hydroxycholesterol and 27-hydroxycholesterol: A link between cholesterol metabolism and antiviral defense 193
Plasma levels of 24S-hydroxycholesterol reflect brain volumes in patients without objective cognitive impairment but not in those with Alzheimer's disease 192
Changes in human plasma levels of the brain specific oxysterol 24S-hydroxycholesterol during progression of multiple sclerosis 191
Antiviral oxysterols are present in human milk at diverse stages of lactation 191
Familial Alzheimer's disease associated with heterozygous NPC1 mutation 189
Inhibition of herpes simplex-1 virus replication by 25-hydroxycholesterol and 27-hydroxycholesterol 189
Genetic connections between neurological disorders and cholesterol metabolism 187
Enhanced molecular release from elderly bone samples using collagenase I: insights into fatty acid metabolism alterations 186
Mitochondrial dysfunctions in 7-ketocholesterol-treated 158N oligodendrocytes without or with α-tocopherol: Impacts on the cellular profil of tricarboxylic cycle-associated organic acids, long chain saturated and unsaturated fatty acids, oxysterols, cholesterol and cholesterol precursors 186
Cholesterol defect is marked across multiple rodent models of Huntington's disease and is manifest in astrocytes 183
Hsp22 overexpression induces myocardial hypertrophy, senescence and reduced life span through enhanced oxidative stress 183
Individual Comparison of Cholesterol Metabolism in Normal and Tumour Areas in Radical Prostatectomy Specimens from Patients with Prostate Cancer: Results of the CHOMECAP Study 183
Biological conditions related to frailty influence the behavior of renal stem/progenitor cells grown as nephrospheres 181
Sex‐difference in flux of 27‐hydroxycholesterol in the brain 181
Cholesterol-loaded nanoparticles ameliorate synaptic and cognitive function in Huntington's disease mice 180
Biological variation of Serum Amyloid A in healthy subjects 179
Cholesterol biosynthesis pathway is disturbed in YAC128 mice and is modulated by huntingtin mutation 178
Metabolic consequences of mitochondrial coenzyme A deficiency in patients with PANK2 mutations 177
Trend of 25-hydroxycholesterol and 27-hydroxycholesterol plasma levels in patients affected by active chronic hepatitis B virus infection and inactive carriers 177
NAD(+)-Dependent Activation of Sirt1 Corrects the Phenotype in a Mouse Model of Mitochondrial Disease 176
Insights into kinetics, release, and behavioral effects of brain-targeted hybrid nanoparticles for cholesterol delivery in Huntington's disease 175
24S-hydroxycholesterol in plasma: A marker of cholesterol turnover in neurodegenerative diseases 174
Antibody response after two doses of the SARS-CoV-2 Comirnaty vaccine in a Covid-19 positive and Covid-19 negative Italian healthcare workers cohort 174
Elective Laparoscopic Sigmoidectomy Reduces IL-6 Serum Levels in Uncomplicated Recurrent Diverticulitis 173
Plasma 24S-hydroxycholesterol and caudate MRI in pre-manifest and early Huntington's disease 172
Upregulation of brain renin angiotensin system by 27-hydroxycholesterol in Alzheimer's disease 171
Early and brain region-specific decrease of de novo cholesterol biosynthesis in Huntington's disease: A cross-validation study in Q175 knock-in mice 171
Oxysterols and Parkinson's disease: evidence that levels of 24S-hydroxycholesterol in cerebrospinal fluid correlates with the duration of the disease 171
Liver X receptors constrain tumor development and metastasis dissemination in PTEN-deficient prostate cancer 170
Lipid droplets dependent or independent cytoprotective activities of unsaturated fatty acids, Lorenzo's oil and sulfo-N-succinimidyl oleate on 7-ketocholesterol-induced oxidative stress, organelle dysfunction and cell death on 158N and ARPE-19 cells: Cell targets and benefits of sulfo-N-succinimidyl oleate 170
Plasma 24S-hydroxycholesterol correlation with markers of Huntington disease progression 169
Oxysterols and multiple sclerosis: Physiopathology, evolutive biomarkers and therapeutic strategy 169
Levels of 7-oxocholesterol in cerebrospinal fluid are more than one thousand times lower than reported in multiple sclerosis 167
Progressive dysfunction of the cholesterol biosynthesis pathway in the R6/2 mouse model of Huntington's disease 165
International descriptive and interventional survey for oxycholesterol determination by gas- and liquid-chromatographic methods 165
Therapeutic Applications of Oxysterols and Derivatives in Age-Related Diseases, Infectious and Inflammatory Diseases, and Cancers 164
Induction of peroxisomal changes in oligodendrocytes treated with 7-ketocholesterol: Attenuation by α-tocopherol 164
Evidence for sex difference in the CSF/plasma albumin ratio in ~20 000 patients and 335 healthy volunteers 164
Whole body cholesterol metabolism is impaired in Huntington's disease 163
Role of Diet and Nutrients in SARS-CoV-2 Infection: Incidence on Oxidative Stress, Inflammatory Status and Viral Production 160
High levels of 15-oxygenated steroids in circulation of patients with multiple sclerosis: Fact or fi ction? 160
Intestinal permeability and Ménière's disease 160
The impairment of cholesterol metabolism in Huntington disease 159
Study of cholesterol metabolism in Huntington's disease 158
Totale 22.344
Categoria #
all - tutte 98.931
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 98.931


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022959 0 0 168 93 83 93 70 73 47 79 93 160
2022/20231.701 224 470 153 76 103 274 69 65 116 41 56 54
2023/20241.507 48 50 62 55 201 307 283 56 209 28 41 167
2024/20255.104 268 636 265 200 353 191 375 127 568 770 511 840
2025/202611.747 1.088 1.019 1.080 1.375 1.205 522 1.557 558 923 856 811 753
2026/20271.632 574 551 507 0 0 0 0 0 0 0 0 0
Totale 27.876