LEONI, VALERIO
 Distribuzione geografica
Continente #
NA - Nord America 9.951
AS - Asia 7.778
EU - Europa 4.473
SA - Sud America 1.413
AF - Africa 193
OC - Oceania 22
Continente sconosciuto - Info sul continente non disponibili 4
Totale 23.834
Nazione #
US - Stati Uniti d'America 9.744
SG - Singapore 2.781
CN - Cina 1.515
VN - Vietnam 1.219
HK - Hong Kong 1.202
BR - Brasile 1.092
IT - Italia 941
RU - Federazione Russa 886
DE - Germania 554
IE - Irlanda 495
SE - Svezia 412
FR - Francia 255
GB - Regno Unito 238
IN - India 189
ID - Indonesia 144
UA - Ucraina 138
AR - Argentina 136
FI - Finlandia 128
CA - Canada 122
BD - Bangladesh 111
KR - Corea 111
JP - Giappone 84
IQ - Iraq 81
ZA - Sudafrica 72
NL - Olanda 65
PL - Polonia 65
TR - Turchia 65
EC - Ecuador 63
ES - Italia 63
AT - Austria 62
MX - Messico 52
CH - Svizzera 40
CO - Colombia 36
PK - Pakistan 35
PH - Filippine 31
SA - Arabia Saudita 30
UZ - Uzbekistan 28
CL - Cile 26
MA - Marocco 22
MD - Moldavia 20
JO - Giordania 19
KE - Kenya 19
VE - Venezuela 19
AU - Australia 18
DK - Danimarca 17
RO - Romania 16
TN - Tunisia 15
AE - Emirati Arabi Uniti 13
EG - Egitto 13
PY - Paraguay 13
MY - Malesia 12
AZ - Azerbaigian 11
CZ - Repubblica Ceca 11
ET - Etiopia 11
LB - Libano 11
PE - Perù 11
DZ - Algeria 10
IL - Israele 10
LT - Lituania 9
NP - Nepal 9
AL - Albania 8
OM - Oman 8
PT - Portogallo 8
UY - Uruguay 8
BO - Bolivia 7
KZ - Kazakistan 7
NG - Nigeria 7
BG - Bulgaria 6
IR - Iran 6
JM - Giamaica 6
NO - Norvegia 6
BE - Belgio 5
BY - Bielorussia 5
SN - Senegal 5
TW - Taiwan 5
GR - Grecia 4
HR - Croazia 4
KW - Kuwait 4
NI - Nicaragua 4
PS - Palestinian Territory 4
SC - Seychelles 4
TH - Thailandia 4
TT - Trinidad e Tobago 4
BA - Bosnia-Erzegovina 3
BH - Bahrain 3
CR - Costa Rica 3
CY - Cipro 3
DO - Repubblica Dominicana 3
EU - Europa 3
GH - Ghana 3
GT - Guatemala 3
HN - Honduras 3
KG - Kirghizistan 3
NZ - Nuova Zelanda 3
PA - Panama 3
QA - Qatar 3
RS - Serbia 3
SY - Repubblica araba siriana 3
AM - Armenia 2
AO - Angola 2
Totale 23.798
Città #
Singapore 1.545
Hong Kong 1.174
Ann Arbor 1.140
Fairfield 972
Ashburn 903
San Jose 501
Dublin 479
Wilmington 472
Woodbridge 431
Ho Chi Minh City 392
Seattle 385
Houston 374
Dallas 353
Frankfurt am Main 346
Cambridge 338
Milan 313
Santa Clara 271
Hanoi 266
New York 249
Chicago 226
Hefei 225
Los Angeles 218
Chandler 194
Princeton 192
The Dalles 186
Beijing 176
Dearborn 142
Council Bluffs 133
Moscow 129
São Paulo 126
Lauterbourg 120
Jakarta 104
Seoul 99
Altamura 93
Lawrence 93
San Diego 88
Shanghai 83
Helsinki 80
Jacksonville 76
Buffalo 65
Nanjing 55
Da Nang 54
Munich 49
Tokyo 47
Haiphong 44
Nuremberg 44
London 43
Orem 43
Toronto 41
Warsaw 41
Montreal 39
Baghdad 37
Vienna 37
Guangzhou 36
Monza 35
Rio de Janeiro 34
Andover 33
Rome 32
Lappeenranta 28
Guayaquil 27
Tashkent 27
Biên Hòa 26
Chennai 26
Zurich 26
Denver 25
Johannesburg 25
Paris 25
Poplar 25
Boardman 23
Brooklyn 23
Curitiba 23
Amsterdam 22
Atlanta 22
Belo Horizonte 22
Salt Lake City 22
Shenyang 22
Stockholm 22
Chisinau 20
Kent 20
Amman 19
Ha Long 19
Hangzhou 19
Nanchang 19
Turku 19
Brasília 18
Changsha 18
Mumbai 18
Phoenix 18
Quito 17
Tianjin 17
Ankara 16
Chengdu 16
Desio 16
Nairobi 16
Ninh Bình 16
Porto Alegre 16
Tampa 16
Thái Nguyên 16
Boston 15
Can Tho 15
Totale 15.356
Nome #
CRISPR/Cas9-mediated knockout of Abcd1 and Abcd2 genes in BV-2 cells: novel microglial models for X-linked Adrenoleukodystrophy 520
A microglial cell model for acyl-CoA oxidase 1 deficiency 412
DNA damage in circulating hematopoietic progenitor stem cells as promising biological sensor of frailty 399
Surfactant protein D (SP-D) as a biomarker of SARS-CoV-2 infection 360
DNA damage and reactive oxygen species as promising biological indicators of friality 346
C-reactive protein modifies lipoprotein(a)-related risk for coronary heart disease: the BiomarCaRE project 343
4-IPP, a selective MIF inhibitor, causes mitotic catastrophe in thyroid carcinomas 328
Baseline characteristics of COVID-19 Italian patients admitted to Desio Hospital, Lombardy: a retrospective study 320
The cholesterol metabolite 27-hydroxycholesterol inhibits SARS-CoV-2 and is markedly decreased in COVID-19 patients 317
Bacterial and fungal colonization of the respiratory tract in COVID-19 patients should not be neglected 304
Induction of the intestinal membrane transporters ABCA1 and ABCG8 by 27-hydroxycholesterol through a redox mechanism 260
Monoclonal free light chain detection and quantification: Performances and limits of available laboratory assays 259
Unraveling the complexity of anti-doping analysis: reassessing meldonium detection and doping verdicts in a case study 258
Impairment of Renal and Hematopoietic Stem/Progenitor Cell Compartments in Frailty Syndrome: Link with Oxidative Stress, Plasma Cytokine Profiles and Nuclear DNA Damage 251
Prevalence and species distribution of microorganisms isolated among non-pregnant women affected by vulvovaginal candidiasis: A retrospective study over a 20 year-period 249
Diagnostic use of cerebral and extracerebral oxysterols 242
Spheroplasts, poorly known but clinically relevant particles of urinary sediment 241
Identification of a mechanism promoting mitochondrial sterol accumulation during myocardial ischemia–reperfusion: role of TSPO and STAR 238
On the fluxes of side-chain oxidized oxysterols across blood-brain and blood-CSF barriers and origin of these steroids in CSF (Review) 237
Oxysterols present in Alzheimer's disease brain induce synaptotoxicity by activating astrocytes: A major role for lipocalin-2 236
Antimicrobial Resistance Trends of Escherichia coli Isolates from Outpatient and Inpatient Urinary Infections over a 20-Year Period 233
Antimicrobial Resistance Patterns of Enterobacter cloacae and Klebsiella aerogenes Strains Isolated from Clinical Specimens: A Twenty-Year Surveillance Study 224
Increased production of 27-hydroxycholesterol in human colorectal cancer advanced stage: Possible contribution to cancer cell survival and infiltration 220
Effect of industrial processing and storage procedures on oxysterols in milk and milk products 220
Urinary Sediment Interpretation: The Clinical Role of Spheroplasts 218
Impact of Lipoprotein(a) Level on Low-Density Lipoprotein Cholesterol– or Apolipoprotein B–Related Risk of Coronary Heart Disease 215
SREBP2 gene therapy targeting striatal astrocytes ameliorates Huntington's disease phenotypes 215
Striatal infusion of cholesterol promotes dose‐dependent behavioral benefits and exerts disease‐modifying effects in Huntington's disease mice 214
Cardiovascular Structural and Functional Parameters in Idiopathic Pulmonary Fibrosis at Disease Diagnosis 210
Biological conditions related to friality and their effects on adult renal stem cells cultured as nephrospheres 210
Antibody Response against SARS-CoV-2 after mRNA Vaccine in a Cohort of Hospital Healthy Workers Followed for 17 Months 209
Roles, Functions, and Pathological Implications of Exosomes in the Central Nervous System 206
Oxysterols and Alzheimer's disease 203
Oxysterols as markers of neurological disease--a review 199
Dimethyl fumarate and monomethyl fumarate attenuate oxidative stress and mitochondrial alterations leading to oxiapoptophagy in 158N murine oligodendrocytes treated with 7β-hydroxycholesterol 198
First international descriptive and interventional survey for cholesterol and non-cholesterol sterol determination by gas- and liquid-chromatography–Urgent need for harmonisation of analytical methods 198
Antibody Response after 3-Dose Booster against SARS-CoV-2 mRNA Vaccine in Kidney Transplant Recipients 195
Octadecaneuropeptide (ODN) induces N2a cells differentiation through a PKA/PLC/PKC/MEK/ERK-dependent pathway: Incidence on peroxisome, mitochondria, and lipid profiles 193
Purple corn extract induces long-lasting reprogramming and M2 phenotypic switch of adipose tissue macrophages in obese mice 192
Altered Brain Cholesterol Machinery in a Down Syndrome Mouse Model: A Possible Common Feature with Alzheimer’s Disease 186
Levels of ApoE in cerebrospinal fluid are correlated with Tau and 24S-hydroxycholesterol in patients with cognitive disorders 184
Sleep quality and cerebrospinal fluid oxysterols in degenerative dementias: correlations and possible biomedical implications 184
Side chain oxidized oxysterols in cerebrospinal fluid and the integrity of blood-brain and blood-cerebrospinal fluid barriers 183
MIF/CD74 axis is a target for novel therapies in colon carcinomatosis 183
Biotin attenuation of oxidative stress, mitochondrial dysfunction, lipid metabolism alteration and 7β-hydroxycholesterol-induced cell death in 158N murine oligodendrocytes 183
Oxysterols and neurodegenerative diseases 182
Alteration of Lipid Metabolism in Patients with IPF and Its Association with Disease Severity and Prognosis: A Case–Control Study 179
The Diagnostic Use of the Plasma Quantification of 24S-Hydroxycholesterol and Other Oxysterols in Neurodegenerative Disease 177
Mitochondrial dysfunctions in 7-ketocholesterol-treated 158N oligodendrocytes without or with α-tocopherol: Impacts on the cellular profil of tricarboxylic cycle-associated organic acids, long chain saturated and unsaturated fatty acids, oxysterols, cholesterol and cholesterol precursors 176
Antiviral oxysterols are present in human milk at diverse stages of lactation 176
Modulation of cell proteome by 25-hydroxycholesterol and 27-hydroxycholesterol: A link between cholesterol metabolism and antiviral defense 176
Involvement of 27-Hydroxycholesterol in Mitotane Action on Adrenocortical Carcinoma 176
Plasma levels of 24S-hydroxycholesterol reflect brain volumes in patients without objective cognitive impairment but not in those with Alzheimer's disease 174
Identification of SARS-CoV-2 positivity using machine learning methods on blood count data: External validation of state-of-the-art models. [Identificazione di positività al SARS-CoV-2 attraverso metodi di Machine Learning sui dati dell'esame emocromocitometrico: Validazione esterna di modelli allo stato dell'arte] 173
Individual Comparison of Cholesterol Metabolism in Normal and Tumour Areas in Radical Prostatectomy Specimens from Patients with Prostate Cancer: Results of the CHOMECAP Study 172
Inhibition of herpes simplex-1 virus replication by 25-hydroxycholesterol and 27-hydroxycholesterol 171
The effect of apolipoprotein E (ApoE) genotype on biomarkers of amyloidogenesis, tau pathology and neurodegeneration in Alzheimer's disease 171
Genetic connections between neurological disorders and cholesterol metabolism 171
Hsp22 overexpression induces myocardial hypertrophy, senescence and reduced life span through enhanced oxidative stress 171
Sex‐difference in flux of 27‐hydroxycholesterol in the brain 171
Oxysterols as biomarkers in neurodegenerative diseases 170
Cholesterol defect is marked across multiple rodent models of Huntington's disease and is manifest in astrocytes 166
Association between Diet Quality and Index of Non-Alcoholic Steatohepatitis in a Large Population of People with Type 2 Diabetes: Data from the TOSCA.IT Study 165
Enhanced molecular release from elderly bone samples using collagenase I: insights into fatty acid metabolism alterations 165
Cholesterol biosynthesis pathway is disturbed in YAC128 mice and is modulated by huntingtin mutation 164
Impact of elective surgery on tumor necrosis factor-α, interleukin-6 and quality of life in uncomplicated diverticular disease 163
Biological conditions related to frailty influence the behavior of renal stem/progenitor cells grown as nephrospheres 163
Levels of 7-oxocholesterol in cerebrospinal fluid are more than one thousand times lower than reported in multiple sclerosis 162
Biological variation of Serum Amyloid A in healthy subjects 162
Cholesterol-loaded nanoparticles ameliorate synaptic and cognitive function in Huntington's disease mice 162
Metabolic consequences of mitochondrial coenzyme A deficiency in patients with PANK2 mutations 162
Changes in human plasma levels of the brain specific oxysterol 24S-hydroxycholesterol during progression of multiple sclerosis 160
Antibody response after two doses of the SARS-CoV-2 Comirnaty vaccine in a Covid-19 positive and Covid-19 negative Italian healthcare workers cohort 160
Oxysterols and Parkinson's disease: evidence that levels of 24S-hydroxycholesterol in cerebrospinal fluid correlates with the duration of the disease 159
Trend of 25-hydroxycholesterol and 27-hydroxycholesterol plasma levels in patients affected by active chronic hepatitis B virus infection and inactive carriers 159
24S-hydroxycholesterol in plasma: A marker of cholesterol turnover in neurodegenerative diseases 158
Familial Alzheimer's disease associated with heterozygous NPC1 mutation 157
Plasma 24S-hydroxycholesterol and caudate MRI in pre-manifest and early Huntington's disease 157
NAD(+)-Dependent Activation of Sirt1 Corrects the Phenotype in a Mouse Model of Mitochondrial Disease 157
Progressive dysfunction of the cholesterol biosynthesis pathway in the R6/2 mouse model of Huntington's disease 156
Insights into kinetics, release, and behavioral effects of brain-targeted hybrid nanoparticles for cholesterol delivery in Huntington's disease 156
International descriptive and interventional survey for oxycholesterol determination by gas- and liquid-chromatographic methods 155
Oxysterols in the development of diabetes and cardiovascular diseases 153
Induction of peroxisomal changes in oligodendrocytes treated with 7-ketocholesterol: Attenuation by α-tocopherol 153
The impairment of cholesterol metabolism in Huntington disease 152
Early and brain region-specific decrease of de novo cholesterol biosynthesis in Huntington's disease: A cross-validation study in Q175 knock-in mice 151
Liver X receptors constrain tumor development and metastasis dissemination in PTEN-deficient prostate cancer 149
High levels of 15-oxygenated steroids in circulation of patients with multiple sclerosis: Fact or fi ction? 147
Whole body cholesterol metabolism is impaired in Huntington's disease 147
Evidence for sex difference in the CSF/plasma albumin ratio in ~20 000 patients and 335 healthy volunteers 147
Study of cholesterol metabolism in Huntington's disease 145
Glucose accelerates copper- and ceruloplasmin-induced oxidation of low-density lipoprotein and whole serum 144
Oxysterols and multiple sclerosis: Physiopathology, evolutive biomarkers and therapeutic strategy 144
Therapeutic Applications of Oxysterols and Derivatives in Age-Related Diseases, Infectious and Inflammatory Diseases, and Cancers 143
Elevated 24-hydroxycholesterol levels counteract okadaic acid-induced tau hyperphosphorylation and neuronal morphology impairment 142
Are the CSF levels of 24S-hydroxycholesterol a sensitive biomarker for mild cognitive impairment? 142
Plasma 24S-hydroxycholesterol correlation with markers of Huntington disease progression 140
Intestinal permeability and Ménière's disease 140
Potential diagnostic applications of side chain oxysterols analysis in plasma and cerebrospinal fluid 139
Elective Laparoscopic Sigmoidectomy Reduces IL-6 Serum Levels in Uncomplicated Recurrent Diverticulitis 138
Totale 19.965
Categoria #
all - tutte 84.223
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 84.223


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021379 0 0 0 0 0 0 0 0 0 135 124 120
2021/20221.224 137 128 168 93 83 93 70 73 47 79 93 160
2022/20231.701 224 470 153 76 103 274 69 65 116 41 56 54
2023/20241.507 48 50 62 55 201 307 283 56 209 28 41 167
2024/20255.104 268 636 265 200 353 191 375 127 568 770 511 840
2025/202610.111 1.088 1.019 1.080 1.375 1.205 522 1.557 558 923 784 0 0
Totale 24.608