The aim of the present study was to comprehensively evaluate systemic and local inflammation as well as progression of vascular inflammation in normal and mechanically injured vessels in a large animal model of mild hypercholesterolemia. Our aim was also to test the effect of high-dose statin treatment on these processes.

Busnelli, M., Manzini, S., Froio, A., Vargiolu, A., Cerrito, M., Smolenski, R., et al. (2013). Diet Induced Mild Hypercholesterolemia in Pigs: Local and Systemic Inflammation, Effects on Vascular Injury - Rescue by High-Dose Statin Treatment. PLOS ONE, 8(11), e80588 [10.1371/journal.pone.0080588].

Diet Induced Mild Hypercholesterolemia in Pigs: Local and Systemic Inflammation, Effects on Vascular Injury - Rescue by High-Dose Statin Treatment

BUSNELLI, MARCO;MANZINI, STEFANO;FROIO, ALBERTO;VARGIOLU, ALESSIA;CERRITO, MARIA GRAZIA;SMOLENSKI, RYSZARD TOMASZ;CINTI, ALESSANDRO;LEONE, BIAGIO EUGENIO;BIASI, GIORGIO MARIA;GIOVANNONI, ROBERTO;LAVITRANO, MARIALUISA
2013

Abstract

The aim of the present study was to comprehensively evaluate systemic and local inflammation as well as progression of vascular inflammation in normal and mechanically injured vessels in a large animal model of mild hypercholesterolemia. Our aim was also to test the effect of high-dose statin treatment on these processes.
Articolo in rivista - Articolo scientifico
Inflammation; Vascular Injury; Cholesterol; Swine
English
e80588
Busnelli, M., Manzini, S., Froio, A., Vargiolu, A., Cerrito, M., Smolenski, R., et al. (2013). Diet Induced Mild Hypercholesterolemia in Pigs: Local and Systemic Inflammation, Effects on Vascular Injury - Rescue by High-Dose Statin Treatment. PLOS ONE, 8(11), e80588 [10.1371/journal.pone.0080588].
Busnelli, M; Manzini, S; Froio, A; Vargiolu, A; Cerrito, M; Smolenski, R; Giunti, M; Cinti, A; Zannoni, A; Leone, B; Forni, M; Bacci, M; Biasi, G; Giovannoni, R; Lavitrano, M
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/48306
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