Microorganisms appear as ideal catalysts for chemical conversions. Diverse metabolic routes seem to open doors to the whole range of chemistry. Indeed, a vast amount of scientific papers suggesting new microbial cell factories for old and new products is published every year. However, only very few of them reached industrial relevance. Chemical balances and some metabolic tricks allow natural microorganisms the efficient production of some chemicals, but not others. So first of all it is important to choose metabolically feasible products of value for synthetic chemistry. Here we see a clear task for the chemical and biotechnology industries to communicate for defining the right target molecules. Finally, despite our limited current knowledge, synthetic biology points to a future independent from natural strain backgrounds

Porro, D., Branduardi, P., Saur, M., Mattanovich, D. (2014). Old obstacles and new horizons for microbial chemical production. CURRENT OPINION IN BIOTECHNOLOGY, 30, 101-106 [10.1016/j.copbio.2014.06.009].

Old obstacles and new horizons for microbial chemical production

Porro, D;Branduardi, P;
2014

Abstract

Microorganisms appear as ideal catalysts for chemical conversions. Diverse metabolic routes seem to open doors to the whole range of chemistry. Indeed, a vast amount of scientific papers suggesting new microbial cell factories for old and new products is published every year. However, only very few of them reached industrial relevance. Chemical balances and some metabolic tricks allow natural microorganisms the efficient production of some chemicals, but not others. So first of all it is important to choose metabolically feasible products of value for synthetic chemistry. Here we see a clear task for the chemical and biotechnology industries to communicate for defining the right target molecules. Finally, despite our limited current knowledge, synthetic biology points to a future independent from natural strain backgrounds
Articolo in rivista - Articolo scientifico
Industrial biothechnology, bioeconomy
English
2014
2014
30
101
106
reserved
Porro, D., Branduardi, P., Saur, M., Mattanovich, D. (2014). Old obstacles and new horizons for microbial chemical production. CURRENT OPINION IN BIOTECHNOLOGY, 30, 101-106 [10.1016/j.copbio.2014.06.009].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/101423
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