DIPARTIMENTO DI BIOTECNOLOGIE E BIOSCIENZE (attivo dal 01/01/1998 al 30/09/2012)
Cannabinoid-precipitated withdrawal: a time-course study of the behavioral aspect and its correlation with cannabinoid receptors and G protein expression
1998 Rubino, T; Patrini, G; Massi, P; Fuzio, D; Viganò, D; Giagnoni, G; Parolaro, D
A role of nitric oxide in WIN 55,212-2 tolerance in mice.
1998 Spina, E; Trovati, A; Parolaro, D; Giagnoni, G
Cross-tolerance and convergent dependence between morphine and cannabimimetic agent WIN 55,212-2 in the guinea-pig ileum myenteric plexus
1999 Basilico, L; Parolaro, D; Colleoni, M; Costa, B; Giagnoni, G
Precipitated and spontaneous withdrawal in rats tolerant to anandamide
2000 Costa, B; Giagnoni, G; Colleoni, M
Chronic delta-9-tetrahydrocannabinol treatment increases cAMP levels and cAMP-dependent protein kinase activity in some rat brain regions
2000 Rubino, T; Viganò, D; Massi, P; Spinello, M; Zagato, E; Giagnoni, G; Parolaro, D
Antiinflammatory action of endocannabinoid palmitoylethanolamide and the synthetic cannabinoid nabilone in a model of acute inflammation in the rat.
2002 Conti, S; Costa, B; Colleoni, M; Parolaro, D; Giagnoni, G
Therapeutic effect of the endogenous fatty acid amide, palmitoylethanolamide, in rat acute inflammation: inhibition of nitric oxide and cyclo-oxygenase systems.
2002 Costa, B; Conti, S; Giagnoni, G; Colleoni, M
Vanilloid TRPV1 receptor mediates the antihyperalgesic effect of the nonpsychoactive cannabinoid, cannabidiol, in a rat model of acute inflammation.
2004 Costa, B; Giagnoni, G; Franke, C; Trovato, A; Colleoni, M
Oral anti-inflammatory activity of cannabidiol, a non-psychoactive constituent of cannabis, in acute carrageenan-induced inflammation in the rat paw.
2004 Costa, B; Colleoni, M; Conti, S; Parolaro, D; Franke, C; Trovato, A; Giagnoni, G
Repeated treatment with the synthetic cannabinoid WIN 55,212-2 reduces both hyperalgesia and production of pronociceptive mediators in a rat model of neuropathic pain
2004 Costa, B; Colleoni, M; Conti, S; Trovato, A; Bianchi, M; Sotgiu, M; Giagnoni, G
Effect of the cannabinoid CB1 receptor antagonist, SR14716, on nociceptive response and nerve demyelination in rodents with chronic constriction injury of the sciatic nerve
2005 Costa, B; Trovato, A; Colleoni, M; Giagnoni, G; Zarini, E; Croci, T
AM404, an inhibitor of anandamide uptake, prevents pain behaviour and modulates cytokine and apoptotic pathways in a rat model of neuropathic pain
2006 Costa, B; Siniscalco, D; Trovato, A; Comelli, F; Sotgiu, M; Colleoni, M; Maione, S; Rossi, F; Giagnoni, G
The inhibition of monoacylglycerol lipase by URB602 showed an anti-inflammatory and anti-nociceptive effect in a murine model of acute inflammation
2007 Comelli, F; Giagnoni, G; Bettoni, I; Colleoni, M; Costa, B
The non-psychoactive cannabis constituent cannabidiol is an orally effective therapeutic agent in rat chronic inflammatory and neuropathic pain
2007 Costa, B; Trovato, A; Comelli, F; Giagnoni, G; Colleoni, M
The endogenous fatty acid amide, palmitoylethanolamide, has anti-allodynic and anti-hyperalgesic effects in a murine model of neuropathic pain: involvement of CB(1), TRPV1 and PPARgamma receptors and neurotrophic factors
2008 Costa, B; Comelli, F; Bettoni, I; Colleoni, M; Giagnoni, G
Fructose-fused gamma-butyrolactones and lactams, synthesis and biological evaluation as GABA receptor ligands
2008 Araujo, A; Nicotra, F; Costa, B; Giagnoni, G; Cipolla, L
Glial TLR4 receptor as new target to treat neuropathic pain: efficacy of a new receptor antagonist in a model of peripheral nerve injury in mice
2008 Bettoni, I; Comelli, F; Rossini, C; Granucci, F; Giagnoni, G; Peri, F; Costa, B
Antihyperalgesic effect of a Cannabis sativa extract in a rat model of neuropathic pain: mechanisms involved
2008 Comelli, F; Giagnoni, G; Bettoni, I; Colleoni, M; Costa, B
Synthesis and biological evaluation of novel rigid 1,4-benzodiazepine-2,5-dione chimeric scaffolds
2008 Araujo, A; Nicotra, F; Airoldi, C; Costa, B; Giagnoni, G; Fumagalli, P; Cipolla, L
Beneficial effects of a Cannabis sativa extract treatment on diabetes-induced neuropathy and oxidative stress
2009 Comelli, F; Bettoni, I; Colleoni, M; Giagnoni, G; Costa, B