MOLOGNI, LUCA
MOLOGNI, LUCA
DIPARTIMENTO DI MEDICINA E CHIRURGIA (SCHOOL OF MEDICINE AND SURGERY)
Inhibition of the ABL kinase activity blocks the proliferation of BCR/ABL+ leukemic cells and induces apoptosis
1997 Gambacorti-Passerini, C; Le Coutre, P; Mologni, L; Fanelli, M; Bertazzoli, C; Marchesi, E; Di Nicola, M; Biondi, A; Corneo, G; Belotti, D; Pogliani, E; Lydon, N
Anaplastic Lymphoma kinase assay, reagents and composition thereof
2003 Pinna, L; Donella Deana, A; Marin, O; Mologni, L; Gunby, R; GAMBACORTI PASSERINI, C; Scapozza, L
Unique substrate specificity of Anaplastic Lymphoma Kinase (ALK): development of phosphoacceptor peptides for the assay of ALK activity
2005 Donella deana, A; Marin, O; Cesaro, L; Gunby, R; Ferrarese, A; Tartari, C; Mologni, L; Scapozza, L; GAMBACORTI PASSERINI, C; Pinna, L
Expression, purification, and inhibition of human RET tyrosine kinase
2005 Mologni, L; Sala, E; Riva, B; Cesaro, L; Cazzaniga, S; Redaelli, S; Marin, O; Pasquato, N; Donella Deana, A; GAMBACORTI PASSERINI, C
Characterization of mouse myotilin and its promoter
2005 Mologni, L; Moza, M; Lalowski, M; Carpen, O
Structural insights into the ATP binding pocket of the anaplastic lymphoma kinase by site-directed mutagenesis, inhibitor binding analysis, and homology modeling
2006 Gunby, R; Ahmed, S; Sottocornola, R; Gasser, M; Redaelli, S; Mologni, L; Tartari, C; Belloni, V; GAMBACORTI PASSERINI, C; Scapozza, L
A rapid method for the purification of wild-type and V804M mutant ret catalytic domain: A tool to study thyroid cancer
2006 Sala, E; Mologni, L; Cazzaniga, S; Papinutto, E; GAMBACORTI PASSERINI, C
Inhibition of RET tyrosine kinase by SU5416
2006 Mologni, L; Sala, E; Cazzaniga, S; Rostagno, R; Kuoni, T; Puttini, M; Bain, J; Cleris, L; Redaelli, S; Riva, B; Formelli, F; Scapozza, L; GAMBACORTI PASSERINI, C
Bcr-Abl stabilizes beta-catenin in chronic myeloid leukemia through its tyrosine phosphorylation
2007 Coluccia, A; Vacca, A; Dunach, M; Mologni, L; Redaelli, S; Bustos, V; Benati, D; Pinna, L; GAMBACORTI PASSERINI, C
Oncogenic fusion tyrosine kinases as molecular targets for anti-cancer therapy
2007 Gunby, R; Sala, E; Tartari, C; Puttini, M; GAMBACORTI PASSERINI, C; Mologni, L
Targeted deletion of the muscular dystrophy gene myotilin does not perturb muscle structure or function in mice
2007 Moza, M; Mologni, L; Trokovic, R; Faulkner, G; Partanen, J; Carpen, O
Sorafenib functions to potently suppress RET tyrosine kinase activity by direct enzymatic inhibition and promoting RET lysosomal degradation independent of proteasomal targeting
2007 Plaza menacho, I; Mologni, L; Sala, E; GAMBACORTI PASSERINI, C; Magee, A; Links, T; Hofstra, R; Barford, D; Isacke, C
Alfa-carboline inhibitors of npm-alk, ret, and bcr-abl
2008 GAMBACORTI PASSERINI, C; Mologni, L; Scapozza, L; Ahmed, S; Goekjian, P; Gueyrard, D; Popowycz, F; Joseph, B; Schneider, C; Garcia, P
BRAF silencing by short hairpin RNA or chemical blockade by PLX4032 leads to different responses in melanoma and thyroid carcinoma cells
2008 Sala, E; Mologni, L; Truffa, S; Gaetano, C; Bollag, G; GAMBACORTI PASSERINI, C
Characterization of compound 584, an Abl kinase inhibitor with lasting effects
2008 Puttini, M; Redaelli, S; Moretti, L; Brussolo, S; Gunby, R; Mologni, L; Marchesi, E; Cleris, L; Donella deana, A; Drueckes, P; Sala, E; Lucchini, V; Kubbutat, M; Formelli, F; Zambon, A; Scapozza, L; GAMBACORTI PASSERINI, C
Role of TMPRSS2/ERG in cellular transformation
2009 Magistroni, V; Sanselicio, S; Mologni, L; Reid, J; Gariboldi, M; GAMBACORTI PASSERINI, C
Resistance Profile of the BCR/ABL Inhibitor Bosutinib Using a High Throughput random Mutagenesis Assay
2009 Piazza, R; Redaelli, S; Ceccon, M; Mogavero, A; Marega, M; Mologni, L; Boschelli, F; Pogliani, E; GAMBACORTI PASSERINI, C
Valproic acid enhances bosutinib cytotoxicity in colon cancer cells
2009 Mologni, L; Cleris, L; Magistroni, V; Piazza, R; Boschelli, F; Formelli, F; GAMBACORTI PASSERINI, C
Synthesis, structure-activity relationship and crystallographic studies of 3-substituted indolin-2-one RET inhibitors
2010 Mologni, L; Rostagno, R; Brussolo, S; Knowles, P; Kjaer, S; Murray Rust, J; Rosso, E; Zambon, A; Scapozza, L; Mcdonald, N; Lucchini, V; GAMBACORTI PASSERINI, C
Inhibitors of the RET tyrosine kinase based on a 2-(alkylsulfanyl)-4-(3- thienyl)nicotinonitrile scaffold
2010 Brandt, W; Mologni, L; Preu, L; Lemcke, T; Gambacorti-Passerini, C; Kunick, C