Sfoglia per Autore
Cardiac microtissues from human pluripotent stem cells recapitulate the phenotype of long-QT syndrome
2021 Giacomelli, E; Sala, L; Oostwaard, D; Bellin, M
MTMR4 SNVs modulate ion channel degradation and clinical severity in congenital long QT syndrome: insights in the mechanism of action of protective modifier genes
2021 Lee, Y; Sala, L; Mura, M; Rocchetti, M; Pedrazzini, M; Ran, X; Mak, T; Crotti, L; Sham, P; Torre, E; Zaza, A; Schwartz, P; Tse, H; Gnecchi, M
Human-iPSC-Derived Cardiac Stromal Cells Enhance Maturation in 3D Cardiac Microtissues and Reveal Non-cardiomyocyte Contributions to Heart Disease
2020 Giacomelli, E; Meraviglia, V; Campostrini, G; Cochrane, A; Cao, X; van Helden, R; Krotenberg Garcia, A; Mircea, M; Kostidis, S; Davis, R; van Meer, B; Jost, C; Koster, A; Mei, H; Miguez, D; Mulder, A; Ledesma-Terron, M; Pompilio, G; Sala, L; Salvatori, D; Slieker, R; Sommariva, E; de Vries, A; Giera, M; Semrau, S; Tertoolen, L; Orlova, V; Bellin, M; Mummery, C
Isogenic Sets of hiPSC-CMs Harboring Distinct KCNH2 Mutations Differ Functionally and in Susceptibility to Drug-Induced Arrhythmias
2020 Brandao, K; van den Brink, L; Miller, D; Grandela, C; van Meer, B; Mol, M; de Korte, T; Tertoolen, L; Mummery, C; Sala, L; Verkerk, A; Davis, R
Simultaneous measurement of excitation-contraction coupling parameters identifies mechanisms underlying contractile responses of hiPSC-derived cardiomyocytes
2019 van Meer, B; Krotenberg, A; Sala, L; Davis, R; Eschenhagen, T; Denning, C; Tertoolen, L; Mummery, C
Cardiac Repolarization and Stem Cells: An Emerging Path Toward Precision Medicine
2019 Gnecchi, M; Sala, L; Schwartz, P
Long QT Syndrome modelling with cardiomyocytes derived from human-induced pluripotent stem cells
2019 Sala, L; Gnecchi, M; Schwartz, P
Precision versus traditional medicine - Clinical questions trigger progress in basic science: A favor not always returned
2019 Schwartz, P; Sala, L
From patient-specific induced pluripotent stem cells to clinical translation in long QT syndrome Type 2
2019 Schwartz, P; Gnecchi, M; Dagradi, F; Castelletti, S; Parati, G; Spazzolini, C; Sala, L; Crotti, L
A platform for assessing pro- and anti-arrhythmic effects of drugs based on isogenic human iPSC-derived cardiomyocytes
2019 Campostrini, G; Sala, L; Ward-van Oostwaard, D; van Meer, B; Tertoolen, L; Bartulos-Encinas, O; Braam, S; Ijzerman, A; Mummery, C; Bellin, M
Calmodulinopathy: Functional Effects of CALM Mutations and Their Relationship With Clinical Phenotypes
2018 Badone, B; Ronchi, C; Kotta, M; Sala, L; Ghidoni, A; Crotti, L; Zaza, A
Quantification of Muscle Contraction In Vitro and In Vivo Using MUSCLEMOTION Software: From Stem Cell-Derived Cardiomyocytes to Zebrafish and Human Hearts
2018 van Meer, B; Sala, L; Tertoolen, L; Smith, G; Burton, F; Mummery, C
Calmodulinopathy: A Novel, Life-Threatening Clinical Entity Affecting the Young
2018 Kotta, M; Sala, L; Ghidoni, A; Badone, B; Ronchi, C; Parati, G; Zaza, A; Crotti, L
Musclemotion: A versatile open software tool to quantify cardiomyocyte and cardiac muscle contraction in vitro and in vivo
2018 Sala, L; Van Meer, B; Tertoolen, L; Bakkers, J; Bellin, M; Davis, R; Denning, C; Dieben, M; Eschenhagen, T; Giacomelli, E; Grandela, C; Hansen, A; Holman, E; Jongbloed, M; Kamel, S; Koopman, C; Lachaud, Q; Mannhardt, I; Mol, M; Mosqueira, D; Orlova, V; Passier, R; Ribeiro, M; Saleem, U; Smith, G; Burton, F; Mummery, C
Action potential contour contributes to species differences in repolarization response to b-adrenergic stimulation
2018 Sala, L; Hegyi, B; Bartolucci, C; Altomare, C; Rocchetti, M; Váczi, K; Mostacciuolo, G; Szentandrássy, N; Severi, S; Pál Nánási, P; Zaza, A
Electrophysiological analysis of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) using multi-electrode arrays (MEAs)
2017 Sala, L; Ward-Van Oostwaard, D; Tertoolen, L; Mummery, C; Bellin, M
Three-dimensional cardiac microtissues composed of cardiomyocytes and endothelial cells co-differentiated from human pluripotent stem cells
2017 Giacomelli, E; Bellin, M; Sala, L; van Meer, B; Tertoolen, L; Orlova, V; Mummery, C
Integrating cardiomyocytes from human pluripotent stem cells in safety pharmacology: has the time come?
2017 Sala, L; Bellin, M; Mummery, C
Elucidating arrhythmogenic mechanisms of long-QT syndrome CALM1-F142L mutation in patient-specific induced pluripotent stem cell-derived cardiomyocytes
2017 Rocchetti, M; Sala, L; Dreizehnter, L; Crotti, L; Sinnecker, D; Mura, M; Pane, S; Altomare, C; Torre, E; Mostacciuolo, G; Severi, S; Porta, A; De Ferrari, G; George, A; Schwartz, P; Gnecchi, M; Moretti, A; Zaza, A
A new hERG allosteric modulator rescues genetic and drug-induced long-QT syndrome phenotypes in cardiomyocytes from isogenic pairs of patient induced pluripotent stem cells
2016 Sala, L; Yu, Z; Ward-van Oostwaard, D; van Veldhoven, J; Moretti, A; Laugwitz, K; Mummery, C; Ijzerman, A; Bellin, M
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