A series of meta-analyses of randomised controlled trials raised the question of whether the three-drug combination of CAP (cyclophosphamide, doxorubicin, and cisplatin) was more or less effective than optimal-dose single-agent carboplatin for women with advanced ovarian cancer.

Parmar, M., Torri, V., Bonaventura, A., Bonazzi, C., Colombo, N., Delaloye, J., et al. (1998). ICON2: Randomised trial of single-agent carboplatin against three-drug combination of CAP (cyclophosphamide, doxorubicin, and cisplatin) in women with ovarian cancer. THE LANCET, 352(9140), 1571-1576 [10.1016/S0140-6736(98)04119-1].

ICON2: Randomised trial of single-agent carboplatin against three-drug combination of CAP (cyclophosphamide, doxorubicin, and cisplatin) in women with ovarian cancer

COLOMBO, NICOLETTA;
1998

Abstract

A series of meta-analyses of randomised controlled trials raised the question of whether the three-drug combination of CAP (cyclophosphamide, doxorubicin, and cisplatin) was more or less effective than optimal-dose single-agent carboplatin for women with advanced ovarian cancer.
Articolo in rivista - Articolo scientifico
Aged; Alopecia; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cisplatin; Cyclophosphamide; Doxorubicin; Female; Humans; Leukopenia; Middle Aged; Ovarian Neoplasms; Proportional Hazards Models; Survival Analysis; Thrombocytopenia
English
1998
352
9140
1571
1576
none
Parmar, M., Torri, V., Bonaventura, A., Bonazzi, C., Colombo, N., Delaloye, J., et al. (1998). ICON2: Randomised trial of single-agent carboplatin against three-drug combination of CAP (cyclophosphamide, doxorubicin, and cisplatin) in women with ovarian cancer. THE LANCET, 352(9140), 1571-1576 [10.1016/S0140-6736(98)04119-1].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/97403
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