Arterial distensibility reflects mechanical properties of the arterial wall and have, thus a clearcut clinical relevance. This because an arterial distensibility reduction is associated with an increased pulse pressure, an increased cardiac work and a reduced diastolic vital organ perfusion. In recent years it has been demonstrated that arterial distensibility is reduced in marked and mild hypercholesterolemia, in a manner independent from arterial blood pressure values. Arterial mechanical properties are also impaired in heart failure, this leading to a further cardiac damage. This important vascular properties however, can be improved by appropriate treatment, while the time needed for that can be extremely long.

Giannattasio, C., Failla, M., Calchera, I., Grieco, N., Scandola, L., Grappiolo, A., et al. (1999). Pharmacological improvement of large arteries properties. PATHOLOGIE BIOLOGIE, 47(7), 744-751.

Pharmacological improvement of large arteries properties

GIANNATTASIO, CRISTINA
Primo
;
FAILLA, MONICA
Secondo
;
CALCHERA, IVAN FRANCESCO;GRIECO, NICCOLO';MANCIA, GIUSEPPE
Ultimo
1999

Abstract

Arterial distensibility reflects mechanical properties of the arterial wall and have, thus a clearcut clinical relevance. This because an arterial distensibility reduction is associated with an increased pulse pressure, an increased cardiac work and a reduced diastolic vital organ perfusion. In recent years it has been demonstrated that arterial distensibility is reduced in marked and mild hypercholesterolemia, in a manner independent from arterial blood pressure values. Arterial mechanical properties are also impaired in heart failure, this leading to a further cardiac damage. This important vascular properties however, can be improved by appropriate treatment, while the time needed for that can be extremely long.
Articolo in rivista - Articolo scientifico
Arteries; Blood Pressure; Heart Failure; Humans; Hypercholesterolemia; Hypertension; Hypolipidemic Agents; Vasodilation
English
744
751
8
Giannattasio, C., Failla, M., Calchera, I., Grieco, N., Scandola, L., Grappiolo, A., et al. (1999). Pharmacological improvement of large arteries properties. PATHOLOGIE BIOLOGIE, 47(7), 744-751.
Giannattasio, C; Failla, M; Calchera, I; Grieco, N; Scandola, L; Grappiolo, A; Mancia, G
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/59419
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