This paper explores the use of Large Language Models (LLMs) in mental health to assist psychologists and psychiatrists with diagnostic decision-making according to the ICD-11 classification system. ICD-11 is the 11th revision of the International Classification of Diseases, a globally used diagnostic tool for health conditions, including mental, behavioural, and neurodevelopmental disorders. In detail, we propose LLMind Chat, an AI-powered tool with a user-friendly interface designed to support mental health professionals in their diagnostic processes. LLMind Chat leverages a Retrieval Augmented Generation (RAG) model based on the Gemma 2 (27B parameters), specifically adapted to the context of the ICD-11. This RAG model combines the strengths of Gemma 2 with a comprehensive knowledge base derived from the ICD-11, allowing it to access and process relevant information from the classification manual in real-time. LLMind's diagnostic accuracy was rigorously evaluated against the DSM-5-TR Clinical Cases manual, using automated metrics and mental health professionals’ expert validation. The result suggests that LLMind Chat can serve as a reliable decision-support tool, enhancing diagnostic reasoning and potentially reducing misclassifications.

Cremaschi, M., Ditolve, D., Curcio, C., Panzeri, A., Spoto, A., Maurino, A. (2025). Decoding the mind: A RAG-LLM on ICD-11 for decision support in psychology. EXPERT SYSTEMS WITH APPLICATIONS, 279(15 June 2025) [10.1016/j.eswa.2025.127191].

Decoding the mind: A RAG-LLM on ICD-11 for decision support in psychology

Cremaschi, Marco
Primo
;
Maurino, Andrea
2025

Abstract

This paper explores the use of Large Language Models (LLMs) in mental health to assist psychologists and psychiatrists with diagnostic decision-making according to the ICD-11 classification system. ICD-11 is the 11th revision of the International Classification of Diseases, a globally used diagnostic tool for health conditions, including mental, behavioural, and neurodevelopmental disorders. In detail, we propose LLMind Chat, an AI-powered tool with a user-friendly interface designed to support mental health professionals in their diagnostic processes. LLMind Chat leverages a Retrieval Augmented Generation (RAG) model based on the Gemma 2 (27B parameters), specifically adapted to the context of the ICD-11. This RAG model combines the strengths of Gemma 2 with a comprehensive knowledge base derived from the ICD-11, allowing it to access and process relevant information from the classification manual in real-time. LLMind's diagnostic accuracy was rigorously evaluated against the DSM-5-TR Clinical Cases manual, using automated metrics and mental health professionals’ expert validation. The result suggests that LLMind Chat can serve as a reliable decision-support tool, enhancing diagnostic reasoning and potentially reducing misclassifications.
Articolo in rivista - Articolo scientifico
Clinical decision support; Diagnostic reasoning; DSM5; Healthcare; ICD-11; Large language models; Mental health; Prompt Engineering; Psychology; Retrieval Augmented Generation;
English
29-mar-2025
2025
279
15 June 2025
127191
open
Cremaschi, M., Ditolve, D., Curcio, C., Panzeri, A., Spoto, A., Maurino, A. (2025). Decoding the mind: A RAG-LLM on ICD-11 for decision support in psychology. EXPERT SYSTEMS WITH APPLICATIONS, 279(15 June 2025) [10.1016/j.eswa.2025.127191].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/554901
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