Truncated Singular Value Decomposition (SVD) has always been a key algorithm in modern machine learning. Scientists and researchers use this applied mathematics method in many fields. Despite a long history and prevalence, the issue of how to choose the best truncation level still remains an open challenge. In this paper, we describe a new algorithm, akin a the discrete optimization method, that relies on the Receiver Operating Characteristics (ROC) Areas Under the Curve (AUCs) computation. We explore a concrete application of the algorithm to a bioinformatics problem, i.e. the prediction of biomolecular annotations. We applied the algorithm to nine different datasets and the obtained results demostrate the effectiveness of our technique.

Chicco, D., Masseroli, M. (2013). A discrete optimization approach for SVD best truncation choice based on ROC curves. In Proceedings of the 2013 Thirteenth IEEE International Conference on Bioinformatics and Bioengineering: BIBE 2013 (pp.1-4). IEEE Computer Society [10.1109/BIBE.2013.6701705].

A discrete optimization approach for SVD best truncation choice based on ROC curves

Chicco, D
;
2013

Abstract

Truncated Singular Value Decomposition (SVD) has always been a key algorithm in modern machine learning. Scientists and researchers use this applied mathematics method in many fields. Despite a long history and prevalence, the issue of how to choose the best truncation level still remains an open challenge. In this paper, we describe a new algorithm, akin a the discrete optimization method, that relies on the Receiver Operating Characteristics (ROC) Areas Under the Curve (AUCs) computation. We explore a concrete application of the algorithm to a bioinformatics problem, i.e. the prediction of biomolecular annotations. We applied the algorithm to nine different datasets and the obtained results demostrate the effectiveness of our technique.
paper
discrete optimization approach; SVD best truncation choice; ROC-AUC curves; truncated singular value decomposition; machine learning; mathematics method; receiver operating characteristic area under the curve; bioinformatics problem; biomolecular annotation prediction
English
13th IEEE International Conference on BioInformatics and BioEngineering, IEEE BIBE 2013 - 10 November 2013 through 13 November 2013
2013
Nikita, SK; Fotiadis, DI
Proceedings of the 2013 Thirteenth IEEE International Conference on Bioinformatics and Bioengineering: BIBE 2013
9781479931637
2013
1
4
6701705
reserved
Chicco, D., Masseroli, M. (2013). A discrete optimization approach for SVD best truncation choice based on ROC curves. In Proceedings of the 2013 Thirteenth IEEE International Conference on Bioinformatics and Bioengineering: BIBE 2013 (pp.1-4). IEEE Computer Society [10.1109/BIBE.2013.6701705].
File in questo prodotto:
File Dimensione Formato  
Chicco-2013-IEEE BIBE-VoR.pdf

Solo gestori archivio

Descrizione: Intervento a convegno
Tipologia di allegato: Publisher’s Version (Version of Record, VoR)
Licenza: Tutti i diritti riservati
Dimensione 253.12 kB
Formato Adobe PDF
253.12 kB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/435459
Citazioni
  • Scopus 16
  • ???jsp.display-item.citation.isi??? 1
Social impact