Purpose: This study tested the efficacy of digital-health home intervention for people within the Alzheimer’s disease (AD)-continuum. Methods: Thirty people within the AD continuum were randomly assigned to a telerehabilitation (ABILITY; 6 males, Mage=78.2 ± 3.95) or treatment as usual (TAU; 8 males, Mage=77.13 ± 6.38), performing cognitive and physical activities at home for six weeks. The ABILITY intervention additionally included a digital platform enabling communication between the hospital and the patient’s home. Efficiency, such as adherence, perceived fit of demands and skills, usability, and effectiveness measures, including neuropsychological level, neuropsychiatric symptoms, and autonomy in daily living, were collected before (T0), after the treatment (T1), and at the 1-year-follow-up (T2). Results: The ABILITY program was efficient, with a higher adherence (81% vs. 62%), a higher perceived fit of demands and skills than TAU (p[removed] TAU) emerged on the global cognitive level, especially in language, executive functions, and memory domains. Moreover, a treatment carry-over effect (1-year follow-up) was observed in global cognitive functions (especially language) (ABILITY > TAU), behavioral symptoms, and caregiver distress (TAU > ABILITY). Conclusions: Our preliminary findings suggest that ABILITY is a promising eHealth intervention to improve at-home treatment adherence and to preserve cognitive and behavioral abilities.

Rossetto, F., Isernia, S., Realdon, O., Borgnis, F., Blasi, V., Pagliari, C., et al. (2023). A digital health home intervention for people within the Alzheimer's disease continuum: results from the Ability-TelerehABILITation pilot randomized controlled trial. ANNALS OF MEDICINE, 55(1), 1080-1091 [10.1080/07853890.2023.2185672].

A digital health home intervention for people within the Alzheimer's disease continuum: results from the Ability-TelerehABILITation pilot randomized controlled trial

Realdon, Olivia;Mantovani, Fabrizia;
2023

Abstract

Purpose: This study tested the efficacy of digital-health home intervention for people within the Alzheimer’s disease (AD)-continuum. Methods: Thirty people within the AD continuum were randomly assigned to a telerehabilitation (ABILITY; 6 males, Mage=78.2 ± 3.95) or treatment as usual (TAU; 8 males, Mage=77.13 ± 6.38), performing cognitive and physical activities at home for six weeks. The ABILITY intervention additionally included a digital platform enabling communication between the hospital and the patient’s home. Efficiency, such as adherence, perceived fit of demands and skills, usability, and effectiveness measures, including neuropsychological level, neuropsychiatric symptoms, and autonomy in daily living, were collected before (T0), after the treatment (T1), and at the 1-year-follow-up (T2). Results: The ABILITY program was efficient, with a higher adherence (81% vs. 62%), a higher perceived fit of demands and skills than TAU (p[removed] TAU) emerged on the global cognitive level, especially in language, executive functions, and memory domains. Moreover, a treatment carry-over effect (1-year follow-up) was observed in global cognitive functions (especially language) (ABILITY > TAU), behavioral symptoms, and caregiver distress (TAU > ABILITY). Conclusions: Our preliminary findings suggest that ABILITY is a promising eHealth intervention to improve at-home treatment adherence and to preserve cognitive and behavioral abilities.
Articolo in rivista - Articolo scientifico
Alzheimer’s disease; Dementia; Disability; Mild Cognitive Impairment; Rehabilitation; Telerehabilitation;
English
17-mar-2023
2023
55
1
1080
1091
open
Rossetto, F., Isernia, S., Realdon, O., Borgnis, F., Blasi, V., Pagliari, C., et al. (2023). A digital health home intervention for people within the Alzheimer's disease continuum: results from the Ability-TelerehABILITation pilot randomized controlled trial. ANNALS OF MEDICINE, 55(1), 1080-1091 [10.1080/07853890.2023.2185672].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/406735
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