Purpose Assess long-term quality of life (HR-QoL) and socio-economic impact in COVID-19-related ARDS (C-ARDS) survivors. Methods C-ARDS survivors were followed up at 6 months in this prospective, cohort study. HR-QoL was assessed using SF-36 and EQ-5D-5L, and the socio-economic burden of COVID-19 was evaluated with a dedicated questionnaire. Clinical data were prospectively recorded. Results Seventy-nine survivors, age 63 [57-71], 84% male, were enrolled. The frequency of EQ-5D-5L reported problems was significantly higher among survivors compared to normal, in mobility, usual activities, and self-care; anxiety and depression and pain were not different. SF-36 scores were lower than the reference population, and physical and mental summary scores were below normal in 52% and 33% of the subjects, respectively. In the multivariable analysis, prolonged hospital length of stay (OR 1.45; p 0.02) and two or more comorbidities on admission (OR 7.42; p 0.002) were significant predictors of impaired “physical” and “mental” HR-QoL, respectively. A total of 38% subjects worsened social relations, 42% changed their employment status, and 23% required personal care support. Conclusions C-ARDS survivors have long-term impairment in HR-QoL and socio-economic problems. Prolonged hospital stay and previous comorbidities are risk factors for developing health-related issues.

Umbrello, M., Miori, S., Sanna, A., Lassola, S., Baruzzo, E., Penzo, D., et al. (2022). High rates of impaired quality of life and social and economic problems at 6 months after COVID-19-related ARDS. JOURNAL OF ANESTHESIA, ANALGESIA AND CRITICAL CARE, 2 [10.1186/s44158-022-00048-5].

High rates of impaired quality of life and social and economic problems at 6 months after COVID-19-related ARDS

Andrea Sanna;Elena Baruzzo;Angelo Colombo;Sandra Magnoni
2022

Abstract

Purpose Assess long-term quality of life (HR-QoL) and socio-economic impact in COVID-19-related ARDS (C-ARDS) survivors. Methods C-ARDS survivors were followed up at 6 months in this prospective, cohort study. HR-QoL was assessed using SF-36 and EQ-5D-5L, and the socio-economic burden of COVID-19 was evaluated with a dedicated questionnaire. Clinical data were prospectively recorded. Results Seventy-nine survivors, age 63 [57-71], 84% male, were enrolled. The frequency of EQ-5D-5L reported problems was significantly higher among survivors compared to normal, in mobility, usual activities, and self-care; anxiety and depression and pain were not different. SF-36 scores were lower than the reference population, and physical and mental summary scores were below normal in 52% and 33% of the subjects, respectively. In the multivariable analysis, prolonged hospital length of stay (OR 1.45; p 0.02) and two or more comorbidities on admission (OR 7.42; p 0.002) were significant predictors of impaired “physical” and “mental” HR-QoL, respectively. A total of 38% subjects worsened social relations, 42% changed their employment status, and 23% required personal care support. Conclusions C-ARDS survivors have long-term impairment in HR-QoL and socio-economic problems. Prolonged hospital stay and previous comorbidities are risk factors for developing health-related issues.
Articolo in rivista - Articolo scientifico
Health-related quality of life, COVID-19, Critical illness, ARDS, C-ARDS, Socio-economic status
English
2022
Umbrello, M., Miori, S., Sanna, A., Lassola, S., Baruzzo, E., Penzo, D., et al. (2022). High rates of impaired quality of life and social and economic problems at 6 months after COVID-19-related ARDS. JOURNAL OF ANESTHESIA, ANALGESIA AND CRITICAL CARE, 2 [10.1186/s44158-022-00048-5].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/396391
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