Background: Cerebral cavernous malformations (CCMs) are low-flow vascular malformations made up of dilated vascular spaces without intervening parenchyma that can occur throughout the central nervous system. CCMs can occur sporadically or in familial forms. Presentation is diverse, ranging from asymptomatic discoveries to drug-resistant epilepsy and hemorrhages. Methods: We describe the surgical management of CCMs in pediatric patients at Bambino Gesù Children's Hospital in Rome over the last 10 years. The cases have been stratified based on the clinical presentation and the relevant literature is discussed accordingly. Results: We discuss the rationale and technique used in these cases based on their presentation, as well as the generally positive outcomes we achieved with early surgical management, use of intra-operative ultrasound (ioUS) and intraoperative neuromonitoring. Conclusions: Surgical management of pediatric CCMs is a safe and effective strategy, low rates of postoperative morbidity and partial resection were observed.

Calloni, T., Carai, A., Lioi, F., Cavaliere, M., DE Benedictis, A., Rossi, S., et al. (2022). Surgical management of pediatric intracranial CCM: a 10-year single center experience. JOURNAL OF NEUROSURGICAL SCIENCES [10.23736/S0390-5616.22.05574-6].

Surgical management of pediatric intracranial CCM: a 10-year single center experience

Calloni, Tommaso;Cavaliere, Marilou;Giussani, Carlo G;
2022

Abstract

Background: Cerebral cavernous malformations (CCMs) are low-flow vascular malformations made up of dilated vascular spaces without intervening parenchyma that can occur throughout the central nervous system. CCMs can occur sporadically or in familial forms. Presentation is diverse, ranging from asymptomatic discoveries to drug-resistant epilepsy and hemorrhages. Methods: We describe the surgical management of CCMs in pediatric patients at Bambino Gesù Children's Hospital in Rome over the last 10 years. The cases have been stratified based on the clinical presentation and the relevant literature is discussed accordingly. Results: We discuss the rationale and technique used in these cases based on their presentation, as well as the generally positive outcomes we achieved with early surgical management, use of intra-operative ultrasound (ioUS) and intraoperative neuromonitoring. Conclusions: Surgical management of pediatric CCMs is a safe and effective strategy, low rates of postoperative morbidity and partial resection were observed.
Articolo in rivista - Articolo scientifico
Scientifica
Pediatric cavernoma; CCM; Intracranial vascular malformation; Intraoperative ultrasound cavernoma; Cavernous angioma;
English
Calloni, T., Carai, A., Lioi, F., Cavaliere, M., DE Benedictis, A., Rossi, S., et al. (2022). Surgical management of pediatric intracranial CCM: a 10-year single center experience. JOURNAL OF NEUROSURGICAL SCIENCES [10.23736/S0390-5616.22.05574-6].
Calloni, T; Carai, A; Lioi, F; Cavaliere, M; DE Benedictis, A; Rossi, S; Randi, F; Rossi Espagnet, M; Trivisano, M; Cesario, C; Pisaneschi, E; Marasi, A; Savioli, A; Giussani, C; Marras, C
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10281/367451
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