The complete 1H and 13C NMR assignments are reported for the antithrombotic (21R)- and (21S)-argatroban by 1D and 2D NMR experiments (HSQC, HMBC, NOESY and 1H-1H COSY). Some well-resolved signals could be used for an accurate measurement of the diastereomeric composition of argatroban.
Colombo, D., Ferraboschi, P., Grisenti, P., Legnani, L. (2008). Complete 1H and 13C assignments of (21R) and (21S) diastereomers of argatroban. MAGNETIC RESONANCE IN CHEMISTRY, 46(1), 99-102 [10.1002/mrc.2122].
Complete 1H and 13C assignments of (21R) and (21S) diastereomers of argatroban
Legnani Laura
2008
Abstract
The complete 1H and 13C NMR assignments are reported for the antithrombotic (21R)- and (21S)-argatroban by 1D and 2D NMR experiments (HSQC, HMBC, NOESY and 1H-1H COSY). Some well-resolved signals could be used for an accurate measurement of the diastereomeric composition of argatroban.
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