Reconstructing the evolutionary history of a set of species is a central task in computational biology. In real data, it is often the case that some information is missing: the Incomplete Directed Perfect Phylogeny (IDPP) problem asks, given a collection of species described by a set of binary characters with some unknown states, to complete the missing states in such a way that the result can be explained with a directed perfect phylogeny. Pe’er et al. [SICOMP 2004] proposed a solution that takes O~ (nm) time (the O~ (· ) notation suppresses polylog factors) for n species and m characters. Their algorithm relies on pre-existing dynamic connectivity data structures: a computational study recently conducted by Fernández-Baca and Liu showed that, in this context, complex data structures perform worse than simpler ones with worse asymptotic bounds. This gives us the motivation to look into the particular properties of the dynamic connectivity problem in this setting, so as to avoid the use of sophisticated data structures as a blackbox. Not only are we successful in doing so, and give a much simpler O(nmlog n) -time algorithm for the IDPP problem; our insights into the specific structure of the problem lead to an asymptotically optimal O(nm) -time algorithm.
Bernardini, G., Bonizzoni, P., Gawrychowski, P. (2021). Incomplete Directed Perfect Phylogeny in Linear Time. In Algorithms and Data Structures (pp.172-185). GEWERBESTRASSE 11, CHAM, CH-6330, SWITZERLAND : Springer Science and Business Media Deutschland GmbH [10.1007/978-3-030-83508-8_13].
Incomplete Directed Perfect Phylogeny in Linear Time
Bonizzoni P.
Co-primo
Membro del Collaboration Group
;
2021
Abstract
Reconstructing the evolutionary history of a set of species is a central task in computational biology. In real data, it is often the case that some information is missing: the Incomplete Directed Perfect Phylogeny (IDPP) problem asks, given a collection of species described by a set of binary characters with some unknown states, to complete the missing states in such a way that the result can be explained with a directed perfect phylogeny. Pe’er et al. [SICOMP 2004] proposed a solution that takes O~ (nm) time (the O~ (· ) notation suppresses polylog factors) for n species and m characters. Their algorithm relies on pre-existing dynamic connectivity data structures: a computational study recently conducted by Fernández-Baca and Liu showed that, in this context, complex data structures perform worse than simpler ones with worse asymptotic bounds. This gives us the motivation to look into the particular properties of the dynamic connectivity problem in this setting, so as to avoid the use of sophisticated data structures as a blackbox. Not only are we successful in doing so, and give a much simpler O(nmlog n) -time algorithm for the IDPP problem; our insights into the specific structure of the problem lead to an asymptotically optimal O(nm) -time algorithm.
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