Despite important advances in diagnosis and treatment, heart failure (HF) remains a syndrome with substantial morbidity and dismal prognosis. Although implementation and optimization of existing technologies and drugs may lead to better management of HF, new or alternative strategies are desirable. In this regard, basic science is expected to give fundamental inputs, by expanding the knowledge of the pathways underlying HF development and progression, identifying approaches that may improve HF detection and prognostic stratification, and finding novel treatments. Here, we discuss recent basic science insights that encompass major areas of translational research in HF and have high potential clinical impact.

Ameri, P., Schiattarella, G., Crotti, L., Torchio, M., Bertero, E., Rodolico, D., et al. (2020). Novel basic science insights to improve the management of heart failure: Review of the working group on cellular and molecular biology of the heart of the italian society of cardiology. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 21(4) [10.3390/ijms21041192].

Novel basic science insights to improve the management of heart failure: Review of the working group on cellular and molecular biology of the heart of the italian society of cardiology

Crotti L;
2020

Abstract

Despite important advances in diagnosis and treatment, heart failure (HF) remains a syndrome with substantial morbidity and dismal prognosis. Although implementation and optimization of existing technologies and drugs may lead to better management of HF, new or alternative strategies are desirable. In this regard, basic science is expected to give fundamental inputs, by expanding the knowledge of the pathways underlying HF development and progression, identifying approaches that may improve HF detection and prognostic stratification, and finding novel treatments. Here, we discuss recent basic science insights that encompass major areas of translational research in HF and have high potential clinical impact.
Articolo in rivista - Review Essay
basic; heart failure; mechanisms; research; translational;
English
11-feb-2020
2020
21
4
1192
open
Ameri, P., Schiattarella, G., Crotti, L., Torchio, M., Bertero, E., Rodolico, D., et al. (2020). Novel basic science insights to improve the management of heart failure: Review of the working group on cellular and molecular biology of the heart of the italian society of cardiology. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 21(4) [10.3390/ijms21041192].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/298104
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