Appropriate weaning is of crucial importance for critically ill patients requiring respiratory support. However, a remarkable proportion of them are difficult to wean. Levosimendan is a positive inotropic agent characterized by vasodilatory properties, which is used for the treatment of acute decompensated heart failure or in patients needing inotropic treatment, including cardiogenic shock, septic shock, pulmonary hypertension and right ventricular dysfunction, needed for hemodynamic support in patients with diuretic resistance, and weaning either from ventilator or from extracorporeal membrane oxygenation. This position paper will discuss the use of levosimendan in facilitating weaning from cardiorespiratory support in critically ill patients, according to available evidence and the personal experience of a group of Italian Experts.

Sangalli, F., Bellani, G., Affronti, A., Volpi, F., Feri, M., Marini, M., et al. (2020). Levosimendan to facilitate weaning from cardiorespiratory support in critically ill patients: current evidence and future directions. MINERVA ANESTESIOLOGICA, 86(6), 645-651 [10.23736/S0375-9393.20.14219-6].

Levosimendan to facilitate weaning from cardiorespiratory support in critically ill patients: current evidence and future directions

Sangalli, Fabio
;
Bellani, Giacomo;
2020

Abstract

Appropriate weaning is of crucial importance for critically ill patients requiring respiratory support. However, a remarkable proportion of them are difficult to wean. Levosimendan is a positive inotropic agent characterized by vasodilatory properties, which is used for the treatment of acute decompensated heart failure or in patients needing inotropic treatment, including cardiogenic shock, septic shock, pulmonary hypertension and right ventricular dysfunction, needed for hemodynamic support in patients with diuretic resistance, and weaning either from ventilator or from extracorporeal membrane oxygenation. This position paper will discuss the use of levosimendan in facilitating weaning from cardiorespiratory support in critically ill patients, according to available evidence and the personal experience of a group of Italian Experts.
Articolo in rivista - Review Essay
Scientifica
Weaning; levosimendan
English
Sangalli, F., Bellani, G., Affronti, A., Volpi, F., Feri, M., Marini, M., et al. (2020). Levosimendan to facilitate weaning from cardiorespiratory support in critically ill patients: current evidence and future directions. MINERVA ANESTESIOLOGICA, 86(6), 645-651 [10.23736/S0375-9393.20.14219-6].
Sangalli, F; Bellani, G; Affronti, A; Volpi, F; Feri, M; Marini, M; Quacquarelli, A; Vitale, D; Guarracino, F
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10281/273306
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