To investigate tumor response rate and treatment toxicity of a modified combination chemotherapy consisting of bleomycin (B), methotrexate (M), and CCNU (C) for patients with locally advanced, squamous-cell carcinoma of the vulva (not amenable to resection by standard radical vulvectomy) or recurrent disease (after incomplete resection). Tumor resectability was reassessed in patients who had responded to chemotherapy.

Wagenaar, H., Colombo, N., Vergote, I., Hoctin Boes, G., Zanetta, G., Pecorelli, S., et al. (2001). Bleomycin, methotrexate, and CCNU in locally advanced or recurrent, inoperable, squamous-cell carcinoma of the vulva: An EORTC gynaecological cancer cooperative group study. GYNECOLOGIC ONCOLOGY, 81(3), 348-354 [10.1006/gyno.2001.6180].

Bleomycin, methotrexate, and CCNU in locally advanced or recurrent, inoperable, squamous-cell carcinoma of the vulva: An EORTC gynaecological cancer cooperative group study

COLOMBO, NICOLETTA;
2001

Abstract

To investigate tumor response rate and treatment toxicity of a modified combination chemotherapy consisting of bleomycin (B), methotrexate (M), and CCNU (C) for patients with locally advanced, squamous-cell carcinoma of the vulva (not amenable to resection by standard radical vulvectomy) or recurrent disease (after incomplete resection). Tumor resectability was reassessed in patients who had responded to chemotherapy.
Articolo in rivista - Articolo scientifico
Aged, 80 and over; Bleomycin; Middle Aged; Female; Neoplasm Recurrence, Local; Vulvar Neoplasms; Dose-Response Relationship, Drug; Methotrexate; Humans; Prospective Studies; Antineoplastic Agents; Lomustine; Antineoplastic Combined Chemotherapy Protocols; Aged; Adult; Drug Administration Schedule; Carcinoma, Squamous Cell; Combined Modality Therapy
English
giu-2001
81
3
348
354
none
Wagenaar, H., Colombo, N., Vergote, I., Hoctin Boes, G., Zanetta, G., Pecorelli, S., et al. (2001). Bleomycin, methotrexate, and CCNU in locally advanced or recurrent, inoperable, squamous-cell carcinoma of the vulva: An EORTC gynaecological cancer cooperative group study. GYNECOLOGIC ONCOLOGY, 81(3), 348-354 [10.1006/gyno.2001.6180].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/26704
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