Background: People with HIV daily cope with a chronic disease that requires a complex management. Antiretroviral treatments (highly active antiretroviral treatment, HAART) are effective in slowing HIV progression but it requests a strong compliance. Patients' depression along with negative emotions could affect compliance negatively and deserve attention both from the clinical and research points of view. Indeed, they are associated with faster HIV progression and substance use. A suitable psychological factor that may help people with HIV in the daily management of their disease is the HAART perceived self-efficacy, namely people's beliefs about their capability to be strongly compliant with the HAART treatment. HAART perceived self-efficacy also acts indirectly, affecting depressive symptoms. Methods: Cross-sectional data have been collected through Internet. Participants were 146 people with HIV (gender: 84.2% M, 15.1% F, 0.7% missing data; mean age: M = 40.22, DS = 9.27). Self-report questionnaires were administered. Path analyses were conducted through Amos 18.0. Results: HAART perceived self-efficacy was a significant predictor of low depression and low viral load (respectively β = -.34 p < .001, β = -.20 p < .05). Besides, depression was a significant predictor of low CD4 count (indirect effect β = -.11 p < .01). Such influence was mediated by nervousness, which also showed direct significant effects on CD4 count (β = -.23 p < .01) and substance use (β = .16 p < .05). Fit indices were adequate (CFI and TLI .995, RMSEA .018, χ2 = 9.404 df = 9, p > .05). Conclusion: The study confirms the protective effect of HAART self-efficacy on the health of people with HIV. The negative effect of nervousness and depression suggest the need for psychological assessment in HIV clinical practice. Based on these findings, psychological interventions focused on HAART self-efficacy may provide positive effect on patients' clinical outcome

NORCINI PALA, A., Steca, P. (2011). HAART perceived self-efficacy: a promising psychological factor that may reduce depression and disease progression. In Atti del congresso "6th IAS Conference On HIV Pathogenesis Treatment and Prevention" (pp.64-65). INT MEDICAL PRESS LTD.

HAART perceived self-efficacy: a promising psychological factor that may reduce depression and disease progression

NORCINI PALA, ANDREA;STECA, PATRIZIA
2011

Abstract

Background: People with HIV daily cope with a chronic disease that requires a complex management. Antiretroviral treatments (highly active antiretroviral treatment, HAART) are effective in slowing HIV progression but it requests a strong compliance. Patients' depression along with negative emotions could affect compliance negatively and deserve attention both from the clinical and research points of view. Indeed, they are associated with faster HIV progression and substance use. A suitable psychological factor that may help people with HIV in the daily management of their disease is the HAART perceived self-efficacy, namely people's beliefs about their capability to be strongly compliant with the HAART treatment. HAART perceived self-efficacy also acts indirectly, affecting depressive symptoms. Methods: Cross-sectional data have been collected through Internet. Participants were 146 people with HIV (gender: 84.2% M, 15.1% F, 0.7% missing data; mean age: M = 40.22, DS = 9.27). Self-report questionnaires were administered. Path analyses were conducted through Amos 18.0. Results: HAART perceived self-efficacy was a significant predictor of low depression and low viral load (respectively β = -.34 p < .001, β = -.20 p < .05). Besides, depression was a significant predictor of low CD4 count (indirect effect β = -.11 p < .01). Such influence was mediated by nervousness, which also showed direct significant effects on CD4 count (β = -.23 p < .01) and substance use (β = .16 p < .05). Fit indices were adequate (CFI and TLI .995, RMSEA .018, χ2 = 9.404 df = 9, p > .05). Conclusion: The study confirms the protective effect of HAART self-efficacy on the health of people with HIV. The negative effect of nervousness and depression suggest the need for psychological assessment in HIV clinical practice. Based on these findings, psychological interventions focused on HAART self-efficacy may provide positive effect on patients' clinical outcome
abstract + poster
HIV/AIDS, HAART, Self-efficacy, Depression, HIV progression
English
IAS International AIDS Society Conference
2011
Atti del congresso "6th IAS Conference On HIV Pathogenesis Treatment and Prevention"
2011
16
64
65
none
NORCINI PALA, A., Steca, P. (2011). HAART perceived self-efficacy: a promising psychological factor that may reduce depression and disease progression. In Atti del congresso "6th IAS Conference On HIV Pathogenesis Treatment and Prevention" (pp.64-65). INT MEDICAL PRESS LTD.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/24899
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