BACKGROUND: The aim of this study was to evaluate feasibility, safety and efficacy in day surgery of electrochemotherapy (ECT) using bleomycin in non-melanoma head and neck skin cancer. METHODS: We performed a prospective study on fifteen patients treated at the General Surgery Department at University Hospital of Tor Vergata, Rome between April 2011 and February 2013. RESULTS: We observed 100% complete response evaluated with WHO criteria at 6 weeks after treatment. No partial response was achieved. CONCLUSIONS: ECT is a simple, highly effective and safe treatment for head and neck non melanoma skin cancer. In our experience ECT can be performed safely in Day Surgery also in patients ASA III. Side effects associated with ECT are minimal and the treatment is well tolerated also by older patients, with minimal impairment of organ function and healthy tissues and with good esthetic results. We would encourage this treatment especially for older patients with multiple comorbidities, in which conventional surgical approach is not easily practicable.

Montuori, M., Santurro, L., Feliziani, A., DE Sanctis, F., Ricciardi, E., Gaudio, D., et al. (2018). Electrochemotherapy for basocellular and squamocellular head and neck cancer: Preliminary experience in Day Surgery Unit. GIORNALE ITALIANO DI DERMATOLOGIA E VENEREOLOGIA, 153(1), 19-25 [10.23736/S0392-0488.16.05373-6].

Electrochemotherapy for basocellular and squamocellular head and neck cancer: Preliminary experience in Day Surgery Unit

Montuori, Mauro
Primo
;
Santurro, Letizia;
2018

Abstract

BACKGROUND: The aim of this study was to evaluate feasibility, safety and efficacy in day surgery of electrochemotherapy (ECT) using bleomycin in non-melanoma head and neck skin cancer. METHODS: We performed a prospective study on fifteen patients treated at the General Surgery Department at University Hospital of Tor Vergata, Rome between April 2011 and February 2013. RESULTS: We observed 100% complete response evaluated with WHO criteria at 6 weeks after treatment. No partial response was achieved. CONCLUSIONS: ECT is a simple, highly effective and safe treatment for head and neck non melanoma skin cancer. In our experience ECT can be performed safely in Day Surgery also in patients ASA III. Side effects associated with ECT are minimal and the treatment is well tolerated also by older patients, with minimal impairment of organ function and healthy tissues and with good esthetic results. We would encourage this treatment especially for older patients with multiple comorbidities, in which conventional surgical approach is not easily practicable.
No
Articolo in rivista - Articolo scientifico
Scientifica
Basal cell; Bleomycin; Carcinoma; Carcinoma; Electrochemotherapy; Head and neck neoplasms; Squamous cell;
Aged; Aged, 80 and over; Ambulatory Surgical Procedures; Antineoplastic Agents; Bleomycin; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Electrochemotherapy; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Male; Middle Aged; Prospective Studies; Skin Neoplasms; Squamous Cell Carcinoma of Head and Neck; Treatment Outcome
English
19
25
7
Montuori, M., Santurro, L., Feliziani, A., DE Sanctis, F., Ricciardi, E., Gaudio, D., et al. (2018). Electrochemotherapy for basocellular and squamocellular head and neck cancer: Preliminary experience in Day Surgery Unit. GIORNALE ITALIANO DI DERMATOLOGIA E VENEREOLOGIA, 153(1), 19-25 [10.23736/S0392-0488.16.05373-6].
Montuori, M; Santurro, L; Feliziani, A; DE Sanctis, F; Ricciardi, E; Gaudio, D; Campione, E; Bianchi, L; Silvi, M; Rossi, P
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10281/215718
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