Fetal malformations are more frequent in twins than in singletons. The aim of our study was to define the influence of a malformed twin on di-chorionic pregnancy outcomes. We performed a retrospective cohort study of di-chorionic pregnancies delivered between 2000 and 2015. Exclusion criteria were: both twins affected by fetal malformations, double intra-uterine fetal death in pregnancies without fetal malformation, selective feticide and therapeutic pregnancy termination. We compared maternal and fetal outcomes of di-chorionic pregnancies not complicated by fetal malformations with pregnancies affected by a single malformed fetus with conservative management. We included 642 di-chorionic pregnancies: 56 (case group, 8.7%) with one twin affected by a malformation (20 minor, 36 major ones), 586 (control group, 91.3%) without fetal malformation. No differences were found on maternal and not malformed co-twin outcomes when compared to pregnancies with no malformation; case vs control group presented similar rates of preeclampsia (8.9% vs. 10.8%, respectively), intrauterine growth restriction (7.1% vs. 9.4%) and composite adverse neonatal outcomes (19.6% vs. 15.1%). No case of fetal death in not malformed co-twin was reported. Expectant management could be a safe option for both mother and co-twin in case of di-chorionic twin pregnancy complicated by only one malformed fetus.
Algeri, P., Russo, F., Incerti, M., Cozzolino, S., Pelizzoni, F., Bernasconi, D., et al. (2018). Expectant management in di-chorionic pregnancies complicated by discordant anomalous twin. JOURNAL OF PERINATAL MEDICINE, 46(7), 721-727 [10.1515/jpm-2017-0032].
|Citazione:||Algeri, P., Russo, F., Incerti, M., Cozzolino, S., Pelizzoni, F., Bernasconi, D., et al. (2018). Expectant management in di-chorionic pregnancies complicated by discordant anomalous twin. JOURNAL OF PERINATAL MEDICINE, 46(7), 721-727 [10.1515/jpm-2017-0032].|
|Tipo:||Articolo in rivista - Articolo scientifico|
|Carattere della pubblicazione:||Scientifica|
|Presenza di un coautore afferente ad Istituzioni straniere:||No|
|Titolo:||Expectant management in di-chorionic pregnancies complicated by discordant anomalous twin|
|Autori:||Algeri, P; Russo, F; Incerti, M; Cozzolino, S; Pelizzoni, F; Bernasconi, D; Montanelli, L; Locatelli, L; Vergani, P|
ALGERI, PAOLA (Corresponding)
|Data di pubblicazione:||2018|
|Rivista:||JOURNAL OF PERINATAL MEDICINE|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1515/jpm-2017-0032|
|Appare nelle tipologie:||01 - Articolo su rivista|