The cortical and subcortical neural correlates underlying item and order information in verbal short-term memory (STM) were investigated by means of digit span in 29 patients with direct electrical stimulation during awake surgery for removal of a neoplastic lesion. Stimulation of left Broca's area interfered with span, producing significantly more item than order errors, as compared to the stimulation of the supramarginal/angular gyrus, which also interfered with span but, conversely, produced more order than item errors. Similarly, stimulation of the third segment of the left superior longitudinal fasciculus (SLF-III), also known as anterior segment of the arcuate fascicle (AF), produced more order than item errors. Therefore, we obtained two crucial results: first, we were able to distinguish between content and order information storage. Second, we demonstrated that the SLF-III is involved in transferring order information from Geschwind's area to Broca's area. In a few patients, we demonstrated that also order information of nonverbal material was disrupted by left supramarginal gyrus stimulation. Order information is thus likely stored in the supramarginal gyrus, possibly independently from the nature of the material. Hum Brain Mapp 38:3011–3024, 2017. © 2017 Wiley Periodicals, Inc

Papagno, C., Comi, A., Riva, M., Bizzi, A., Vernice, M., Casarotti, A., et al. (2017). Mapping the brain network of the phonological loop. HUMAN BRAIN MAPPING, 38(6), 3011-3024 [10.1002/hbm.23569].

Mapping the brain network of the phonological loop

PAPAGNO, COSTANZA
Primo
;
COMI, ALESSANDRO
Secondo
;
VERNICE, MIRTA;CASAROTTI, ALESSANDRA;
2017

Abstract

The cortical and subcortical neural correlates underlying item and order information in verbal short-term memory (STM) were investigated by means of digit span in 29 patients with direct electrical stimulation during awake surgery for removal of a neoplastic lesion. Stimulation of left Broca's area interfered with span, producing significantly more item than order errors, as compared to the stimulation of the supramarginal/angular gyrus, which also interfered with span but, conversely, produced more order than item errors. Similarly, stimulation of the third segment of the left superior longitudinal fasciculus (SLF-III), also known as anterior segment of the arcuate fascicle (AF), produced more order than item errors. Therefore, we obtained two crucial results: first, we were able to distinguish between content and order information storage. Second, we demonstrated that the SLF-III is involved in transferring order information from Geschwind's area to Broca's area. In a few patients, we demonstrated that also order information of nonverbal material was disrupted by left supramarginal gyrus stimulation. Order information is thus likely stored in the supramarginal gyrus, possibly independently from the nature of the material. Hum Brain Mapp 38:3011–3024, 2017. © 2017 Wiley Periodicals, Inc
Articolo in rivista - Articolo scientifico
arcuate; direct electric stimulation; inferior parietal lobule; memory short-term; neurosurgery; Anatomy; Radiological and Ultrasound Technology; Radiology, Nuclear Medicine and Imaging; Neurology; Neurology (clinical)
English
2017
38
6
3011
3024
reserved
Papagno, C., Comi, A., Riva, M., Bizzi, A., Vernice, M., Casarotti, A., et al. (2017). Mapping the brain network of the phonological loop. HUMAN BRAIN MAPPING, 38(6), 3011-3024 [10.1002/hbm.23569].
File in questo prodotto:
File Dimensione Formato  
hbm23569 copia 2.pdf

Solo gestori archivio

Tipologia di allegato: Publisher’s Version (Version of Record, VoR)
Dimensione 747.03 kB
Formato Adobe PDF
747.03 kB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/164949
Citazioni
  • Scopus 87
  • ???jsp.display-item.citation.isi??? 78
Social impact