The growth of gliomas depends on the balance of factors stimulating or inhibiting angiogenesis, tumor cell invasion and proliferation. The administration of endogenous inhibitors to experimental human gliomas in animal models resulted in a significant inhibition of tumor growth. It is becoming apparent that resistance can develop over time to many types of endogenous inhibitors and seems to be influenced by the tumor type and system of delivery.

Pluderi, M., Lucini, V., Caronzolo, D., Pannacci, M., Costa, F., Carrabba, G., et al. (2003). Long-term inhibition of glioma growth by systemic administration of human PEX. JOURNAL OF NEUROSURGICAL SCIENCES, 47(2), 69-78.

Long-term inhibition of glioma growth by systemic administration of human PEX

Carrabba, G;GIUSSANI, CARLO GIORGIO;
2003

Abstract

The growth of gliomas depends on the balance of factors stimulating or inhibiting angiogenesis, tumor cell invasion and proliferation. The administration of endogenous inhibitors to experimental human gliomas in animal models resulted in a significant inhibition of tumor growth. It is becoming apparent that resistance can develop over time to many types of endogenous inhibitors and seems to be influenced by the tumor type and system of delivery.
Articolo in rivista - Articolo scientifico
Angiogenesis Inhibitors; Animals; Apoptosis; Blotting, Western; Cell Division; Disease Models, Animal; Endothelial Cells; Glioma; Humans; Male; Matrix Metalloproteinase 2; Mice; Mice, Nude; Neoplasm Transplantation; Peptide Fragments; Polymerase Chain Reaction; Recombinant Proteins; Time Factors; Tumor Cells, Cultured
English
2003
47
2
69
78
reserved
Pluderi, M., Lucini, V., Caronzolo, D., Pannacci, M., Costa, F., Carrabba, G., et al. (2003). Long-term inhibition of glioma growth by systemic administration of human PEX. JOURNAL OF NEUROSURGICAL SCIENCES, 47(2), 69-78.
File in questo prodotto:
File Dimensione Formato  
Long term inhibition glioma.pdf

Solo gestori archivio

Dimensione 4.55 MB
Formato Adobe PDF
4.55 MB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/148271
Citazioni
  • Scopus 15
  • ???jsp.display-item.citation.isi??? ND
Social impact