High frequency oscillations in the hippocampal structures recorded during sleep have been proved to be essential for long-term episodic memory consolidation in both animals and in humans. The aim of this study was to test if transcranial Alternating Current Stimulation (tACS) of the dorsolateral prefrontal cortex (DLPFC) in the hippocampal ripple range, applied bi-frontally during encoding, could modulate declarative memory performance, measured immediately after encoding, and after a night’s sleep. An associative word-pair learning test was used. During an evening encoding phase, participants received 1 mA 140. Hz tACS or sham stimulation over both DLPFCs for 10 min while being presented twice with a list of word-pairs. Cued recall performance was investigated 10min after training and the morning following the training session. Forgetting from evening to morning was observed in the sham condition, but not in the 140. Hz stimulation condition. 140. Hz tACS during encoding may have an effect on the consolidation of declarative material.

Ambrus, G., Pisoni, A., Primaßin, A., Turi, Z., Paulus, W., & Antal, A. (2015). Bi-frontal transcranial alternating current stimulation in the ripple range reduced overnight forgetting. FRONTIERS IN CELLULAR NEUROSCIENCE, 9(September), 374 [10.3389/fncel.2015.00374].

Bi-frontal transcranial alternating current stimulation in the ripple range reduced overnight forgetting

PISONI, ALBERTO
Secondo
;
2015

Abstract

High frequency oscillations in the hippocampal structures recorded during sleep have been proved to be essential for long-term episodic memory consolidation in both animals and in humans. The aim of this study was to test if transcranial Alternating Current Stimulation (tACS) of the dorsolateral prefrontal cortex (DLPFC) in the hippocampal ripple range, applied bi-frontally during encoding, could modulate declarative memory performance, measured immediately after encoding, and after a night’s sleep. An associative word-pair learning test was used. During an evening encoding phase, participants received 1 mA 140. Hz tACS or sham stimulation over both DLPFCs for 10 min while being presented twice with a list of word-pairs. Cued recall performance was investigated 10min after training and the morning following the training session. Forgetting from evening to morning was observed in the sham condition, but not in the 140. Hz stimulation condition. 140. Hz tACS during encoding may have an effect on the consolidation of declarative material.
Articolo in rivista - Articolo scientifico
Declarative memory; Ripple oscillation; TACS; Transcranial alternating current stimulation; Verbal associative learning;
Declarative memory; Ripple oscillation; TACS; Transcranial alternating current stimulation; Verbal associative learning; Cellular and Molecular Neuroscience
English
374
Ambrus, G., Pisoni, A., Primaßin, A., Turi, Z., Paulus, W., & Antal, A. (2015). Bi-frontal transcranial alternating current stimulation in the ripple range reduced overnight forgetting. FRONTIERS IN CELLULAR NEUROSCIENCE, 9(September), 374 [10.3389/fncel.2015.00374].
Ambrus, G; Pisoni, A; Primaßin, A; Turi, Z; Paulus, W; Antal, A
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/99573
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