Objective: To identify the classification protocol for stillbirth that minimizes the rate of unexplained causes. Study Design: All stillbirths at > 22 weeks from 1995-2007 underwent a workup inclusive of fetal ultrasonography, amniocentesis for karyotype and cultures, placental histology, fetal autopsy, skin biopsy, total body X-ray, maternal testing for thrombophilias, TORCH, Parvovirus spp, thyroid function, indirect Coombs, Kleiheuer-Betke test, and genital cultures. To such a cohort, we applied the 4 most commonly used classification protocols. Results: The stillbirth rate during the study period was 0.4% (154/37,958). The RoDeCo classification provided the lowest rate of unexplained stillbirth (14.3%) compared with Wigglesworth (47.4%), de Galan-Roosen (18.2%), and Tulip (16.2%) classifications. Mean gestational age at stillbirth in unexplained vs explained stillbirth was similar in the 4 protocols. Conclusion: Adoption of a consistent and appropriate workup protocol can reduce the rate of unexplained stillbirth to 14%. © 2008 Mosby, Inc. All rights reserved.
Vergani, P., Cozzolino, S., Pozzi, E., Cuttin, M.S., Greco, M., Ornaghi, S., et al. (2008). Identifying the causes of stillbirth: a comparison of four classification systems. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 199(3), 319.e1-319.e4 [10.1016/j.ajog.2008.06.098].
Citazione: | Vergani, P., Cozzolino, S., Pozzi, E., Cuttin, M.S., Greco, M., Ornaghi, S., et al. (2008). Identifying the causes of stillbirth: a comparison of four classification systems. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 199(3), 319.e1-319.e4 [10.1016/j.ajog.2008.06.098]. | |
Tipo: | Articolo in rivista - Articolo scientifico | |
Carattere della pubblicazione: | Scientifica | |
Titolo: | Identifying the causes of stillbirth: a comparison of four classification systems | |
Autori: | Vergani, P; Cozzolino, S; Pozzi, E; Cuttin, MS; Greco, M; Ornaghi, S; Lucchini, V | |
Autori: | ||
Data di pubblicazione: | set-2008 | |
Lingua: | English | |
Rivista: | AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY | |
Digital Object Identifier (DOI): | http://dx.doi.org/10.1016/j.ajog.2008.06.098 | |
Appare nelle tipologie: | 01 - Articolo su rivista |