IRIS – Institutional Research Information System
IRIS è il sistema di gestione della ricerca dell’Università degli Studi di Milano-Bicocca.Il repository BOA è il modulo del sistema dedicato alla raccolta e alla disseminazione della produzione scientifica di Ateneo. Le pubblicazioni sono ricercabili per parola chiave attraverso il box nella barra orizzontale in alto oppure, mediante il pulsante Sfoglia, per "Afferenza", "Autore", "Titolo", "Tipologia" o "Settore scientifico-disciplinare".
IRIS contiene inoltre alcuni moduli dedicati alla registrazione dei progetti e dei contratti, e alla reportistica avanzata per le attività di valutazione della ricerca
EnglishObjective To identify independent predictors of adverse neonatal outcome in cases of fetal growth restriction (FGR) at >= 34 weeks.Methods From a cohort of 481 FGR cases delivered at >= 34 weeks, demographic and obstetric variables, fetal biometry and Doppler indices of the uterine, umbilical and fetal middle cerebral arteries available within 2 weeks of delivery, were related to adverse neonatal outcome, defined as admission to the neonatal intensive care unit for indications other than low birth weight alone.Results Logistic regression analysis showed that gestational age (GA) at delivery (odds ratio (OR) = 0.59; 95% Cl, 0.50-0.70), abdominal circumference (AC) centile (OR = 0.69; 95% CI, 0.59-0.81) and umbilical artery (UA) pulsatility index (PI) centile (OR = 1.02; 95% CI, 1.01-1.04) significantly correlated with adverse neonatal outcome. From this model we calculated a score of adverse neonatal outcome expressed by the formula: (UA-PI centile/3) (10 x AC centile) + (10 x (40 GA at delivery in weeks)). Receiver operating characteristics curve analysis demonstrated that a score of >= 25 optimally predicted adverse neonatal outcome (sensitivity of 75%, false-positive rate of 18%). Beyond 37.5 weeks, gestational age no longer had an independent impact on outcome.Conclusions In late preterm or term FGR, GA at delivery is the most important predictor of adverse neonatal outcome. At > 37.5 weeks, delivery may be the best option to minimize adverse outcome in all FGR cases. At 34-37 weeks, a score based on GA at delivery, UA-PI centile and AC centile optimally predicts adverse neonatal outcome. Copyright (C) 2010 ISUOG. Published by John Wiley & Sons, Ltd.
Vergani, P., Roncaglia, N., Ghidini, A., Crippa, I., Cameroni, I., Orsenigo, F., et al. (2010). Can we predict adverse neonatal outcome in late preterm or term fetal growth restriction?. ULTRASOUND IN OBSTETRICS & GYNECOLOGY, 36(2), 166-170 [10.1002/uog.7583].
| Citazione: | Vergani, P., Roncaglia, N., Ghidini, A., Crippa, I., Cameroni, I., Orsenigo, F., et al. (2010). Can we predict adverse neonatal outcome in late preterm or term fetal growth restriction?. ULTRASOUND IN OBSTETRICS & GYNECOLOGY, 36(2), 166-170 [10.1002/uog.7583]. | |
| Tipo: | Articolo in rivista - Articolo scientifico | |
| Carattere della pubblicazione: | Scientifica | |
| Presenza di un coautore afferente ad Istituzioni straniere: | No | |
| Titolo: | Can we predict adverse neonatal outcome in late preterm or term fetal growth restriction? | |
| Autori: | Vergani, P; Roncaglia, N; Ghidini, A; Crippa, I; Cameroni, I; Orsenigo, F; Pezzullo, J | |
| Autori: | ||
| Data di pubblicazione: | 2010 | |
| Lingua: | English | |
| Rivista: | ULTRASOUND IN OBSTETRICS & GYNECOLOGY | |
| Digital Object Identifier (DOI): | http://dx.doi.org/10.1002/uog.7583 | |
| Appare nelle tipologie: | 01 - Articolo su rivista |
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