BACKGROUND: Previous Literature has never evaluated the effectiveness of fiber intake after surgery for obstructed defecation in improving residual constipation and defecation urgency. METHODS: From May 2010 to June 2011, 65 patients were randomly assigned to either the active group (N.=32) or placebo group (N.=33) receiving 3.5 g/day of pure Psyllium fiber or inert compound respectively. During the 6-month follow-up score systems were evaluated: Longo's Obstructed Defecation Syndrome Score, Cleveland Constipation Score; Wexner incontinence Score and Visual Analogic Scale. We also recorded the incidence of postoperative defecation urgency. RESULTS: Active group reported less constipation at 1 week (ODS: 6.25±3.55 vs. 11.94±4.99, P<0.01-CCS: 6.59±2.65 vs. 15.10±3.33, P<0.01) and 6 months (ODS: 3.40±5.26 vs. 4.97±4.21, P<0.05-CCS: 5.00±3.82 vs. 6.63±3.68; P<0.01). Wexner Score was better at t-test in the treatment group (difference from baseline: 0.5 vs. 2.70, P<0.01 after 1 week and-0.17 vs. 1.33, P<0.01 after 6 months). Defecation urgency was less frequent in the treatment group (15.62% vs. 42.42%, P<0.05 at the Χ2 Test). CONCLUSIONS: Early treatment with Psyllium fiber improves early and 6 month results after stapled transanal rectal resection, both in terms of residual constipation and fecal incontinence. It also reduces postoperative defecation urgency.

GABRIELLI, F., MACCHINI, D., GUTTADAURO, A., FRASSANI, S., Bertolini, A., Giussani, C., et al. (2016). Psyllium fiber vs. placebo in early treatment after STARR for obstructed defecation: A randomized double-blind clinical trial. MINERVA CHIRURGICA, 71(2), 98-105.

Psyllium fiber vs. placebo in early treatment after STARR for obstructed defecation: A randomized double-blind clinical trial

GABRIELLI, FRANCESCO
Primo
;
MACCHINI, DANIELE
Secondo
;
GUTTADAURO, ANGELO;FRASSANI, SILVIA;
2016

Abstract

BACKGROUND: Previous Literature has never evaluated the effectiveness of fiber intake after surgery for obstructed defecation in improving residual constipation and defecation urgency. METHODS: From May 2010 to June 2011, 65 patients were randomly assigned to either the active group (N.=32) or placebo group (N.=33) receiving 3.5 g/day of pure Psyllium fiber or inert compound respectively. During the 6-month follow-up score systems were evaluated: Longo's Obstructed Defecation Syndrome Score, Cleveland Constipation Score; Wexner incontinence Score and Visual Analogic Scale. We also recorded the incidence of postoperative defecation urgency. RESULTS: Active group reported less constipation at 1 week (ODS: 6.25±3.55 vs. 11.94±4.99, P<0.01-CCS: 6.59±2.65 vs. 15.10±3.33, P<0.01) and 6 months (ODS: 3.40±5.26 vs. 4.97±4.21, P<0.05-CCS: 5.00±3.82 vs. 6.63±3.68; P<0.01). Wexner Score was better at t-test in the treatment group (difference from baseline: 0.5 vs. 2.70, P<0.01 after 1 week and-0.17 vs. 1.33, P<0.01 after 6 months). Defecation urgency was less frequent in the treatment group (15.62% vs. 42.42%, P<0.05 at the Χ2 Test). CONCLUSIONS: Early treatment with Psyllium fiber improves early and 6 month results after stapled transanal rectal resection, both in terms of residual constipation and fecal incontinence. It also reduces postoperative defecation urgency.
Articolo in rivista - Articolo scientifico
Scientifica
Intussusception; Placebos; Postoperative period; Psyllium;
obstructed defecation, starr, psyllium
English
GABRIELLI, F., MACCHINI, D., GUTTADAURO, A., FRASSANI, S., Bertolini, A., Giussani, C., et al. (2016). Psyllium fiber vs. placebo in early treatment after STARR for obstructed defecation: A randomized double-blind clinical trial. MINERVA CHIRURGICA, 71(2), 98-105.
Gabrielli, F; Macchini, D; Guttadauro, A; Frassani, S; Bertolini, A; Giussani, C; De Simone, M; Cioffi, U
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10281/95222
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