Neuroprotective strategies that limit secondary tissue loss and/or improve functional outcomes have been identified in multiple animal models of ischemic, hemorrhagic, traumatic and nontraumatic cerebral lesions. However, use of these potential interventions in human randomized controlled studies has generally given disappointing results. In this paper, we summarize the current status in terms of neuroprotective strategies, both in the immediate and later stages of acute brain injury in adults. We also review potential new strategies and highlight areas for future research.

Stocchetti, N., Taccone, F., Citerio, G., Pepe, P., Le Roux, P., Oddo, M., et al. (2015). Neuroprotection in acute brain injury: An up-to-date review. CRITICAL CARE, 19(1), 1-11 [10.1186/s13054-015-0887-8].

Neuroprotection in acute brain injury: An up-to-date review

CITERIO, GIUSEPPE;
2015

Abstract

Neuroprotective strategies that limit secondary tissue loss and/or improve functional outcomes have been identified in multiple animal models of ischemic, hemorrhagic, traumatic and nontraumatic cerebral lesions. However, use of these potential interventions in human randomized controlled studies has generally given disappointing results. In this paper, we summarize the current status in terms of neuroprotective strategies, both in the immediate and later stages of acute brain injury in adults. We also review potential new strategies and highlight areas for future research.
Articolo in rivista - Articolo scientifico
Neuroprotection
English
2015
19
1
1
11
186
open
Stocchetti, N., Taccone, F., Citerio, G., Pepe, P., Le Roux, P., Oddo, M., et al. (2015). Neuroprotection in acute brain injury: An up-to-date review. CRITICAL CARE, 19(1), 1-11 [10.1186/s13054-015-0887-8].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/81290
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