Periodontal diseases (PD) are extremely prevalent worldwide, affecting roughly half of the adult population. Any person who has a known susceptibility to periodontal disease and needs prosthetic or implant-prosthetic therapy (PIT) is recommended to undergo genetic testing to see if he/she is genetically predisposed to the development of periodontal disease, because such a patient is at increased risk of developing PD during or after the dental treatment. In other words, it seems beneficial to use a genetic test for identifying those most at risk of PD and to subject them to oral hygiene protocols. Several studies have investigated the association between some markers [such as interleukin (IL)-1, 4, 6, 10] polymorphisms and periodontitis susceptibility but with conflicting results. We recently reported that polymorphisms of IL6 and IL10 constitute risk factors for chronic periodontitis; therefore, genetic tests for these two factors are promising for constructing efficient preventive protocol during or after PIT.

Carinci, F., Palmieri, A., Girardi, A., Cura, F., Lauritano, D. (2015). Genetic Risk Assessment of Periodontal Disease during Dental Treatments. ANNALS OF FORENSIC RESEARCH AND ANALYSIS, 2(1), 1-3.

Genetic Risk Assessment of Periodontal Disease during Dental Treatments

LAURITANO, DORINA
Ultimo
2015

Abstract

Periodontal diseases (PD) are extremely prevalent worldwide, affecting roughly half of the adult population. Any person who has a known susceptibility to periodontal disease and needs prosthetic or implant-prosthetic therapy (PIT) is recommended to undergo genetic testing to see if he/she is genetically predisposed to the development of periodontal disease, because such a patient is at increased risk of developing PD during or after the dental treatment. In other words, it seems beneficial to use a genetic test for identifying those most at risk of PD and to subject them to oral hygiene protocols. Several studies have investigated the association between some markers [such as interleukin (IL)-1, 4, 6, 10] polymorphisms and periodontitis susceptibility but with conflicting results. We recently reported that polymorphisms of IL6 and IL10 constitute risk factors for chronic periodontitis; therefore, genetic tests for these two factors are promising for constructing efficient preventive protocol during or after PIT.
Articolo in rivista - Articolo scientifico
Prosthodontic, periodontitis, genetic susceptibility, genetic test.
English
2015
2
1
1
3
open
Carinci, F., Palmieri, A., Girardi, A., Cura, F., Lauritano, D. (2015). Genetic Risk Assessment of Periodontal Disease during Dental Treatments. ANNALS OF FORENSIC RESEARCH AND ANALYSIS, 2(1), 1-3.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/80249
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