Periodontal diseases (PD) are extremely prevalent worldwide, affecting roughly half of the adult population. Any person who has a known susceptibility to periodontal disease and needs prosthetic or implant-prosthetic therapy (PIT) is recommended to undergo genetic testing to see if he/she is genetically predisposed to the development of periodontal disease, because such a patient is at increased risk of developing PD during or after the dental treatment. In other words, it seems beneficial to use a genetic test for identifying those most at risk of PD and to subject them to oral hygiene protocols. Several studies have investigated the association between some markers [such as interleukin (IL)-1, 4, 6, 10] polymorphisms and periodontitis susceptibility but with conflicting results. We recently reported that polymorphisms of IL6 and IL10 constitute risk factors for chronic periodontitis; therefore, genetic tests for these two factors are promising for constructing efficient preventive protocol during or after PIT.
Carinci, F., Palmieri, A., Girardi, A., Cura, F., Lauritano, D. (2015). Genetic Risk Assessment of Periodontal Disease during Dental Treatments. ANNALS OF FORENSIC RESEARCH AND ANALYSIS, 2(1), 1-3.
Genetic Risk Assessment of Periodontal Disease during Dental Treatments
LAURITANO, DORINAUltimo
2015
Abstract
Periodontal diseases (PD) are extremely prevalent worldwide, affecting roughly half of the adult population. Any person who has a known susceptibility to periodontal disease and needs prosthetic or implant-prosthetic therapy (PIT) is recommended to undergo genetic testing to see if he/she is genetically predisposed to the development of periodontal disease, because such a patient is at increased risk of developing PD during or after the dental treatment. In other words, it seems beneficial to use a genetic test for identifying those most at risk of PD and to subject them to oral hygiene protocols. Several studies have investigated the association between some markers [such as interleukin (IL)-1, 4, 6, 10] polymorphisms and periodontitis susceptibility but with conflicting results. We recently reported that polymorphisms of IL6 and IL10 constitute risk factors for chronic periodontitis; therefore, genetic tests for these two factors are promising for constructing efficient preventive protocol during or after PIT.File | Dimensione | Formato | |
---|---|---|---|
243 AFRA.pdf
accesso aperto
Descrizione: Articolo principale
Dimensione
320.31 kB
Formato
Adobe PDF
|
320.31 kB | Adobe PDF | Visualizza/Apri |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.