Perioral rejuvenation and lip augmentation with hyaluronic acid

In the cosmetic medical area facial rejuvenation with permanent or absorbable fillers requires not only biochemical and biological informations about the molecules used, but also insights into the ageing anatomy and physiology: This article reviews the results of 46 cases undergone to lip augmentation and perioral rejuvenation in the last 1 year. A total of 46 consecutive female patients, between 27 and 60 years of age, with type I and type II lips by Fulton classification were recruited to the study. In all patients both lips were treated. The product was a cross-linked hyaluronic acid (ALIAZIN(R) FL-LIP S IBSA-Lodi, Italy) injected in a single session. The aesthetic evaluation was performed at 3, 6, 9, and 12 months after injection. As to the injection technique the filler has been implanted withdrawing the needle while injecting along the lips margins. After 3 months, 87.88% of participants were satisfied or very satisfied with their treatment result. After 6, 9 and 12 months, 52.73%, 40.67% and 10.67% of participants, respectively, were satisfied or very satisfied. The investigator evaluation rates of acceptable effect (score of 2 or 3) were 96.65%, 40.43%, 28, 39 and 16.79% at 3, 6, 9 and 12 months, respectively. Fining results lasted approximately 5 months with a gradual decline to baseline. The procedure was very well tolerated with only few, mild adverse reactions that resolved spontaneously. In conclusion during first years of clinical use, crosslinked Hyaluronic Acid was proven to be reliable filler preferred by cosmetic doctors an effective and safe facial soft tissue expander and predictable treatment for lip augmentation.