Epidemic of obesity, especially morbid obesity, among children and adolescents, is a key factor associated with the dramatic increase in prevalence of type 2 diabetes mellitus, arterial hypertension, and metabolic syndrome in this population. Furthermore, childhood obesity represents a very important predictor of obesity in adulthood that is related to cardiovascular and cerebrovascular diseases. Overweight and obesity in children and adolescents are associated with impairment of cardiac structure and function. The majority of studies investigated the influence of obesity on left ventricular remodeling. However, the impact of obesity on the right ventricle, both the atria, and myocardial mechanics has been insufficiently studied. The aim of this review article is to summarize all data about heart remodeling in childhood, from cardiac size, throughout systolic and diastolic function, to myocardial mechanics, using a wide range of mainly echocardiographic techniques and parameters. Additionally, we sought to present current knowledge about the influence of weight loss, achieved by various therapeutic approaches, on the improvement of cardiac geometry, structure, and function in obese children and adolescents.

Tadic, M., Cuspidi, C. (2015). Childhood obesity and cardiac remodeling: From cardiac structure to myocardial mechanics. JOURNAL OF CARDIOVASCULAR MEDICINE, 16(8), 538-546 [10.2459/JCM.0000000000000261].

Childhood obesity and cardiac remodeling: From cardiac structure to myocardial mechanics

CUSPIDI, CESARE
Ultimo
2015

Abstract

Epidemic of obesity, especially morbid obesity, among children and adolescents, is a key factor associated with the dramatic increase in prevalence of type 2 diabetes mellitus, arterial hypertension, and metabolic syndrome in this population. Furthermore, childhood obesity represents a very important predictor of obesity in adulthood that is related to cardiovascular and cerebrovascular diseases. Overweight and obesity in children and adolescents are associated with impairment of cardiac structure and function. The majority of studies investigated the influence of obesity on left ventricular remodeling. However, the impact of obesity on the right ventricle, both the atria, and myocardial mechanics has been insufficiently studied. The aim of this review article is to summarize all data about heart remodeling in childhood, from cardiac size, throughout systolic and diastolic function, to myocardial mechanics, using a wide range of mainly echocardiographic techniques and parameters. Additionally, we sought to present current knowledge about the influence of weight loss, achieved by various therapeutic approaches, on the improvement of cardiac geometry, structure, and function in obese children and adolescents.
Articolo in rivista - Articolo scientifico
Bmi; Children; Dolescents; Function; Hypertrophy; Left ventricle; Obesity; Overweight; Right ventricle; Strain;
Childhood obesity and cardiac remodeling:
English
2015
16
8
538
546
none
Tadic, M., Cuspidi, C. (2015). Childhood obesity and cardiac remodeling: From cardiac structure to myocardial mechanics. JOURNAL OF CARDIOVASCULAR MEDICINE, 16(8), 538-546 [10.2459/JCM.0000000000000261].
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/79894
Citazioni
  • Scopus 14
  • ???jsp.display-item.citation.isi??? 13
Social impact