Managing Malaria. Malaria is responsible for two million deaths per year particularly in developing countries, therefore there is great need for the development of cost effective treatment. The synthesis of a library of trisubstituted triazines with potent antimalarial in vitro activity is reported. Among them, five products may be developed as potential leads in the search for new drugs against plasmodial chloroquine-resistant strains.

Melato, S., Prosperi, D., Coghi, P., Basilico, N., & Monti, D. (2008). A combinatorial approach to 2,4,6-trisubstituted triazines with potent antimalarial activity: combining conventional synthesis and microwave-assistance. CHEMMEDCHEM, 3(6), 873-876 [10.1002/cmdc.200700344].

A combinatorial approach to 2,4,6-trisubstituted triazines with potent antimalarial activity: combining conventional synthesis and microwave-assistance

PROSPERI, DAVIDE;
2008

Abstract

Managing Malaria. Malaria is responsible for two million deaths per year particularly in developing countries, therefore there is great need for the development of cost effective treatment. The synthesis of a library of trisubstituted triazines with potent antimalarial in vitro activity is reported. Among them, five products may be developed as potential leads in the search for new drugs against plasmodial chloroquine-resistant strains.
Articolo in rivista - Articolo scientifico
aminoquinolines; antimalarial agents; combinatorial chemistry; microwave assistance; triazines
English
Melato, S., Prosperi, D., Coghi, P., Basilico, N., & Monti, D. (2008). A combinatorial approach to 2,4,6-trisubstituted triazines with potent antimalarial activity: combining conventional synthesis and microwave-assistance. CHEMMEDCHEM, 3(6), 873-876 [10.1002/cmdc.200700344].
Melato, S; Prosperi, D; Coghi, P; Basilico, N; Monti, D
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10281/7907
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