Background: We sought to investigate right ventricular (RV) and right atrial (RA) deformation obtained using 3-dimensional echocardiography (3DE) and 2-dimensional (2DE) strain in subjects with the metabolic syndrome (MS). Methods: This cross-sectional study included 108 untreated subjects with the MS and 75 control subjects similar according to sex and age. The MS was defined by the presence ® 3 American Heart Association/National Heart, Lung, and Blood Institute criteria. All the subjects underwent adequate laboratory analyses and complete 2DE and 3DE examination. Results: 2DE global longitudinal strain of the RV was significantly decreased in the MS group compared with the control subjects (-24 ± 5 vs-27 ± 5%; P < 0.001). Similar results were obtained for the RA longitudinal strain (40 ± 5 vs 44 ± 7%; P < 0.001). Systolic and early diastolic RV and RA strain rates were decreased, whereas late diastolic strain rates were increased among the MS participants compared with the control subjects. 3DE RV ejection fraction was significantly decreased in the MS subjects (55 ± 4 vs 58 ± 4%; P < 0.001). The multivariate analysis of MS criteria showed that systolic blood pressure, waist circumference, and fasting glucose were independently associated with RV and/or RA myocardial function and deformation. Conclusions: RV mechanics and RA mechanics, assessed using 3DE and 2DE strain, were significantly deteriorated in the MS subjects. Among all MS risk factors, systolic blood pressure, abdominal circumference, and fasting glucose were the most responsible for the right heart remodelling. © 2014 Canadian Cardiovascular Society.
Tadic, M., Cuspidi, C., Sljivic, A., Andric, A., Ivanovic, B., Scepanovic, R., et al. (2014). Effects of the metabolic syndrome on right heart mechanics and function. CANADIAN JOURNAL OF CARDIOLOGY, 30(3), 325-331 [10.1016/j.cjca.2013.12.006].
|Citazione:||Tadic, M., Cuspidi, C., Sljivic, A., Andric, A., Ivanovic, B., Scepanovic, R., et al. (2014). Effects of the metabolic syndrome on right heart mechanics and function. CANADIAN JOURNAL OF CARDIOLOGY, 30(3), 325-331 [10.1016/j.cjca.2013.12.006].|
|Tipo:||Articolo in rivista - Articolo scientifico|
|Carattere della pubblicazione:||Scientifica|
|Presenza di un coautore afferente ad Istituzioni straniere:||Si|
|Titolo:||Effects of the metabolic syndrome on right heart mechanics and function.|
|Autori:||Tadic, M; Cuspidi, C; Sljivic, A; Andric, A; Ivanovic, B; Scepanovic, R; Ilic, I; Jozika, L; Marjanovic, T; Celic, V|
CUSPIDI, CESARE (Secondo)
|Data di pubblicazione:||2014|
|Rivista:||CANADIAN JOURNAL OF CARDIOLOGY|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1016/j.cjca.2013.12.006|
|Appare nelle tipologie:||01 - Articolo su rivista|