Patients affected by Parkinson's disease (PD) may present with lower urinary tract (LUT) dysfunction characterized by involuntary detrusor overactivity. We evaluated possible impact of a 2-week course of low frequency 1 Hz repetitive transcranial magnetic stimulation (rTMS) on LUT behavior in eight advanced PD patients complaining of urinary disturbances. We tested the effects of rTMS measuring urodynamic examination and the International Prostate Symptoms Score (IPSS) questionnaire, used for evaluation of subjective LUTS. rTMS was able to improve temporarily LUT behavior in PD patients, increasing bladder capacity and the first sensation of filling phase. Moreover, a reduction of IPSS score was noticed, due to an improvement on filling phase symptoms. The beneficial effects assessed with the IPSS lasted for up to 2 weeks after the end of the stimulation. rTMS seems to be an effective, noninvasive alternative treatment for PD patients with urinary disturbances. © 2009 Movement Disorder Society.

Brusa, L., Agrò, E., Petta, F., Sciobica, F., Torriero, S., LO GERFO, E., et al. (2009). Effects of inhibitory rTMS on bladder function in Parkinson's disease Patients. MOVEMENT DISORDERS, 24(3), 445-448 [10.1002/mds.22434].

Effects of inhibitory rTMS on bladder function in Parkinson's disease Patients

Torriero, Sara;LO GERFO, EMANUELE;
2009

Abstract

Patients affected by Parkinson's disease (PD) may present with lower urinary tract (LUT) dysfunction characterized by involuntary detrusor overactivity. We evaluated possible impact of a 2-week course of low frequency 1 Hz repetitive transcranial magnetic stimulation (rTMS) on LUT behavior in eight advanced PD patients complaining of urinary disturbances. We tested the effects of rTMS measuring urodynamic examination and the International Prostate Symptoms Score (IPSS) questionnaire, used for evaluation of subjective LUTS. rTMS was able to improve temporarily LUT behavior in PD patients, increasing bladder capacity and the first sensation of filling phase. Moreover, a reduction of IPSS score was noticed, due to an improvement on filling phase symptoms. The beneficial effects assessed with the IPSS lasted for up to 2 weeks after the end of the stimulation. rTMS seems to be an effective, noninvasive alternative treatment for PD patients with urinary disturbances. © 2009 Movement Disorder Society.
Articolo in rivista - Articolo scientifico
Bladder functions; Parkinson's disease; rTMS; Transcranial magnetic stimulation; Urodynamic; Aged; Antiparkinson Agents; Female; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Prostatic Neoplasms; Questionnaires; Severity of Illness Index; Time Factors; Transcranial Magnetic Stimulation; Urodynamics; Urinary Bladder, Overactive; Neurology (clinical); Neurology; Medicine (all)
English
2009
24
3
445
448
none
Brusa, L., Agrò, E., Petta, F., Sciobica, F., Torriero, S., LO GERFO, E., et al. (2009). Effects of inhibitory rTMS on bladder function in Parkinson's disease Patients. MOVEMENT DISORDERS, 24(3), 445-448 [10.1002/mds.22434].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/66268
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