Objective: To investigate the effects of transabdominal amnioinfusion (TA) on the histology of amnion (A) and umbilical cord (UC). Study Design: From a cohort of 56 singleton pregnancies with premature rupture of membranes (PROM) at ≤24.6 weeks, we excluded those who did not develop severe oligohydramnios (n=12). Of the 44 patients, 29 consented to TA and 15 declined the procedure. TA was performed with normal saline solution. Result: Women who consented to TA underwent a median of three procedures had a gestational age at PROM of 18.7 weeks and at delivery of 26.1 weeks, with a latency of 50 days. Compared with subjects who declined the procedure, TA had a beneficial effect on clinical variables, mediated primarily by a longer latency. TA was not associated with identifiable effects on the histologic features of A or UC. Conclusion: A and UC histology is not significantly affected by exposure to saline solution even for prolonged periods of time.

Locatelli, A., Andreani, M., Ghidini, A., Verderio, M., Pizzardi, A., Vergani, P., et al. (2008). Amnioinfusion in preterm PROM: effects on amnion and cord histology. JOURNAL OF PERINATOLOGY, 28(2), 97-101 [10.1038/sj.jp.7211876].

Amnioinfusion in preterm PROM: effects on amnion and cord histology

LOCATELLI, ANNA;VERGANI, PATRIZIA;
2008

Abstract

Objective: To investigate the effects of transabdominal amnioinfusion (TA) on the histology of amnion (A) and umbilical cord (UC). Study Design: From a cohort of 56 singleton pregnancies with premature rupture of membranes (PROM) at ≤24.6 weeks, we excluded those who did not develop severe oligohydramnios (n=12). Of the 44 patients, 29 consented to TA and 15 declined the procedure. TA was performed with normal saline solution. Result: Women who consented to TA underwent a median of three procedures had a gestational age at PROM of 18.7 weeks and at delivery of 26.1 weeks, with a latency of 50 days. Compared with subjects who declined the procedure, TA had a beneficial effect on clinical variables, mediated primarily by a longer latency. TA was not associated with identifiable effects on the histologic features of A or UC. Conclusion: A and UC histology is not significantly affected by exposure to saline solution even for prolonged periods of time.
Articolo in rivista - Articolo scientifico
amnioinfusion, PROM
English
97
101
Locatelli, A., Andreani, M., Ghidini, A., Verderio, M., Pizzardi, A., Vergani, P., et al. (2008). Amnioinfusion in preterm PROM: effects on amnion and cord histology. JOURNAL OF PERINATOLOGY, 28(2), 97-101 [10.1038/sj.jp.7211876].
Locatelli, A; Andreani, M; Ghidini, A; Verderio, M; Pizzardi, A; Vergani, P; Salaria, C
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10281/6580
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