A novel approach for multivalent targeting by using gold nanoparticles noncovalently decorated by tight functionalization with a cone-glycocalixarene bearing four mannose units is reported. The targeting efficiency of these multivalent nanoparticles is shown to be remarkably improved compared to that of nanoparticles bearing a monovalent mannosylated derivative. This journal is © the Partner Organisations 2014.

Avvakumova, S., Fezzardi, P., Pandolfi, L., Colombo, M., Sansone, F., Casnati, A., et al. (2014). Gold nanoparticles decorated by clustered multivalent cone-glycocalixarenes actively improve the targeting efficiency toward cancer cells. CHEMICAL COMMUNICATIONS, 50(75), 11029-11032 [10.1039/c4cc03159h].

Gold nanoparticles decorated by clustered multivalent cone-glycocalixarenes actively improve the targeting efficiency toward cancer cells

AVVAKUMOVA, SVETLANA
Primo
;
PANDOLFI, LAURA;COLOMBO, MIRIAM;PROSPERI, DAVIDE
Ultimo
2014

Abstract

A novel approach for multivalent targeting by using gold nanoparticles noncovalently decorated by tight functionalization with a cone-glycocalixarene bearing four mannose units is reported. The targeting efficiency of these multivalent nanoparticles is shown to be remarkably improved compared to that of nanoparticles bearing a monovalent mannosylated derivative. This journal is © the Partner Organisations 2014.
Articolo in rivista - Articolo scientifico
Scientifica
Chemistry; Catalysis; Ceramics and Composites; Electronic, Optical and Magnetic Materials; Surfaces, Coatings and Films; Materials Chemistry; Metals and Alloys
English
Avvakumova, S., Fezzardi, P., Pandolfi, L., Colombo, M., Sansone, F., Casnati, A., et al. (2014). Gold nanoparticles decorated by clustered multivalent cone-glycocalixarenes actively improve the targeting efficiency toward cancer cells. CHEMICAL COMMUNICATIONS, 50(75), 11029-11032 [10.1039/c4cc03159h].
Avvakumova, S; Fezzardi, P; Pandolfi, L; Colombo, M; Sansone, F; Casnati, A; Prosperi, D
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10281/64420
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