We read with interest the study by Cigrowsky et al published in the World Journal of Transplantation. Obesity is a common and serious health issue worldwide. Its incidence has been rapidly and continuously increasing. Obesity causes extensive and heterogeneous comorbidities affecting nearly all organs, including the liver. Severe obesity (SO) has historically been considered a contraindication for liver transplantation due to the increased risk of perioperative complications, mortality, and graft failure. However, recent studies have shown that SO is not associated with worse post-transplant outcomes but rather with higher waiting list mortality. Therefore, severely obese patients should be considered potential candidates and, conversely, prioritized.

Baggio, L., Gianni, S., Carlis, R., Valsecchi, M., Barbaglio, C., Brunetti, A., et al. (2026). Letter to the Editor: Three questions to be answered when evaluating a super obese patient for urgent liver transplant. WORLD JOURNAL OF TRANSPLANTATION, 16(2) [10.5500/wjt.v16.i2.115352].

Letter to the Editor: Three questions to be answered when evaluating a super obese patient for urgent liver transplant

Lauterio A.;
2026

Abstract

We read with interest the study by Cigrowsky et al published in the World Journal of Transplantation. Obesity is a common and serious health issue worldwide. Its incidence has been rapidly and continuously increasing. Obesity causes extensive and heterogeneous comorbidities affecting nearly all organs, including the liver. Severe obesity (SO) has historically been considered a contraindication for liver transplantation due to the increased risk of perioperative complications, mortality, and graft failure. However, recent studies have shown that SO is not associated with worse post-transplant outcomes but rather with higher waiting list mortality. Therefore, severely obese patients should be considered potential candidates and, conversely, prioritized.
Editoriale, introduzione, contributo a forum/dibattito
Bariatric surgery; Body mass index; Comorbidities; Metabolic dysfunction-associated steatotic liver disease; Super-obesity; Urgent liver transplant;
English
18-giu-2026
2026
16
2
115352
open
Baggio, L., Gianni, S., Carlis, R., Valsecchi, M., Barbaglio, C., Brunetti, A., et al. (2026). Letter to the Editor: Three questions to be answered when evaluating a super obese patient for urgent liver transplant. WORLD JOURNAL OF TRANSPLANTATION, 16(2) [10.5500/wjt.v16.i2.115352].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/628992
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