A detailed study on the reaction mechanism of trans-EE and trans-EE/Met Pt-containing anticancer drugs was carried out in order to rationalize the experimental kinetic data concerning the whole process leading to DNA platination.
Alberto, M., Russo, N. (2011). Methionine ligand selectively promotes monofunctional adducts between trans-EE platinum anticancer drug and guanine DNA base. CHEMICAL COMMUNICATIONS, 47(3), 887-889 [10.1039/c0cc03605f].
Methionine ligand selectively promotes monofunctional adducts between trans-EE platinum anticancer drug and guanine DNA base
Alberto M. E.;
2011
Abstract
A detailed study on the reaction mechanism of trans-EE and trans-EE/Met Pt-containing anticancer drugs was carried out in order to rationalize the experimental kinetic data concerning the whole process leading to DNA platination.
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