Acute-on-chronic liver failure (ACLF) is a severe clinical condition for which liver transplantation (LT) is the only curative option. Due to the recipients’ generally poor pre-operative clinical conditions and extensive surgery, post-LT respiratory disorders are very common and significantly contribute to related morbidity and mortality. We report the case of a 49-year-old patient with ACLF grade 3 who has been taken care of by the Respiratory Physiotherapy Team since hospital admission. After the extubation, the patient was supported with non-invasive ventilation and mechanical in-exsufflation; meanwhile, early resistance and functional training were started. No adverse events occurred during physiotherapy sessions, and the patient returned home without respiratory support. Respiratory and physical therapy in the intensive care unit after LT were safe and feasible interventions for this patient. Given the high incidence of postoperative pulmonary complications and the high rehabilitation needs, we suggest that physiotherapy should be provided for ACLF recipients.

Tarello, D., Gioga, F., Lauterio, A., Becchetti, C., Perricone, G., Santi, G., et al. (2025). Respiratory and physical therapy in the intensive care unit after liver transplantation for acute-on-chronic liver failure: a case report. MONALDI ARCHIVES FOR CHEST DISEASE, 95(3) [10.4081/monaldi.2024.2898].

Respiratory and physical therapy in the intensive care unit after liver transplantation for acute-on-chronic liver failure: a case report

Lauterio A.;
2025

Abstract

Acute-on-chronic liver failure (ACLF) is a severe clinical condition for which liver transplantation (LT) is the only curative option. Due to the recipients’ generally poor pre-operative clinical conditions and extensive surgery, post-LT respiratory disorders are very common and significantly contribute to related morbidity and mortality. We report the case of a 49-year-old patient with ACLF grade 3 who has been taken care of by the Respiratory Physiotherapy Team since hospital admission. After the extubation, the patient was supported with non-invasive ventilation and mechanical in-exsufflation; meanwhile, early resistance and functional training were started. No adverse events occurred during physiotherapy sessions, and the patient returned home without respiratory support. Respiratory and physical therapy in the intensive care unit after LT were safe and feasible interventions for this patient. Given the high incidence of postoperative pulmonary complications and the high rehabilitation needs, we suggest that physiotherapy should be provided for ACLF recipients.
Articolo in rivista - Articolo scientifico
acute-on-chronic liver failure; case report; extubation failure; intensive care unit; liver transplantation; noninvasive ventilation; physiotherapy;
English
10-set-2024
2025
95
3
2898
open
Tarello, D., Gioga, F., Lauterio, A., Becchetti, C., Perricone, G., Santi, G., et al. (2025). Respiratory and physical therapy in the intensive care unit after liver transplantation for acute-on-chronic liver failure: a case report. MONALDI ARCHIVES FOR CHEST DISEASE, 95(3) [10.4081/monaldi.2024.2898].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/594564
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