Glutamate has been implicated in the pathogenesis of several diseases on the central nervous system, but recent studies have also suggested that it can be involved also in the onset and course of peripheral neuropathies. Given the increasing evidence of this possibility, several attempts have been performed in order to modulate its activity. Among them, glutamate carboxypeptidase II (GCP II) inhibition demonstrated promising results in different models of peripheral nerve damage, including diabetic and toxic neuropathies
Carozzi, V., & Ceresa, C. (2012). The role of glutamate in diabetic and in chemotherapy induced peripheral neuropathies and its regulation by glutamate carboxypeptidase II. CURRENT MEDICINAL CHEMISTRY, 19(9), 1261-1268 [10.2174/092986712799462694].
Citazione: | Carozzi, V., & Ceresa, C. (2012). The role of glutamate in diabetic and in chemotherapy induced peripheral neuropathies and its regulation by glutamate carboxypeptidase II. CURRENT MEDICINAL CHEMISTRY, 19(9), 1261-1268 [10.2174/092986712799462694]. | |
Tipo: | Articolo in rivista - Review Essay | |
Carattere della pubblicazione: | Scientifica | |
Presenza di un coautore afferente ad Istituzioni straniere: | No | |
Titolo: | The role of glutamate in diabetic and in chemotherapy induced peripheral neuropathies and its regulation by glutamate carboxypeptidase II. | |
Autori: | Carozzi, V; Ceresa, C | |
Autori: | CAROZZI, VALENTINA ALDA (Primo) CERESA, CECILIA (Ultimo) | |
Data di pubblicazione: | 2012 | |
Lingua: | English | |
Rivista: | CURRENT MEDICINAL CHEMISTRY | |
Digital Object Identifier (DOI): | http://dx.doi.org/10.2174/092986712799462694 | |
Appare nelle tipologie: | 01 - Articolo su rivista |
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