Several studies have investigated the behavior of sympathetic cardiovascular drive in essential hypertension, providing conclusive evidence of the adrenergic activation characterizing this condition. These studies have also shown the importance of neuroadrenergic overdrive in the development and progression of the hypertensive state as well as in the pathogenesis of hypertension-related end-organ damage. The information available on the sympathetic nervous system's behavior in 'pseudo-resistant' and 'true resistant' hypertension is much more scarce. This paper will review the available knowledge on this issue by examining the data collected via indirect and direct approaches to investigate adrenergic function in resistant hypertension as well as the effects of pharmacological and non-pharmacological interventions.

Grassi, G., Bombelli, M., Buzzi, S., Volpe, M., Brambilla, G. (2014). Neuroadrenergic disarray in pseudo-resistant and resistant hypertension. HYPERTENSION RESEARCH, 37(6), 479-483 [10.1038/hr.2014.25].

Neuroadrenergic disarray in pseudo-resistant and resistant hypertension

GRASSI, GUIDO;BOMBELLI, MICHELE;BUZZI, SILVIA;VOLPE, MARCO ANTONIO VALENTINO;BRAMBILLA, GIANMARIA
2014

Abstract

Several studies have investigated the behavior of sympathetic cardiovascular drive in essential hypertension, providing conclusive evidence of the adrenergic activation characterizing this condition. These studies have also shown the importance of neuroadrenergic overdrive in the development and progression of the hypertensive state as well as in the pathogenesis of hypertension-related end-organ damage. The information available on the sympathetic nervous system's behavior in 'pseudo-resistant' and 'true resistant' hypertension is much more scarce. This paper will review the available knowledge on this issue by examining the data collected via indirect and direct approaches to investigate adrenergic function in resistant hypertension as well as the effects of pharmacological and non-pharmacological interventions.
Articolo in rivista - Articolo scientifico
Resistant hypertension, Adrenergic nervous system
English
479
483
5
Grassi, G., Bombelli, M., Buzzi, S., Volpe, M., Brambilla, G. (2014). Neuroadrenergic disarray in pseudo-resistant and resistant hypertension. HYPERTENSION RESEARCH, 37(6), 479-483 [10.1038/hr.2014.25].
Grassi, G; Bombelli, M; Buzzi, S; Volpe, M; Brambilla, G
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/56753
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