In the neurointensive care setting, specific considerations of sedation are required; sedation may act as a therapeutic agent itself, when causing a reduction in cerebral metabolic rate of oxygen, cerebral blood flow, and intracranial pressure and in the incidence of seizures. However, the physician must be aware of the effects of every sedative agent on cerebral physiology, in order to obtain beneficial effects and avoid side effects. In this chapter, the effects of sedative agents on cerebral physiology are described in order to provide knowledge for an adequate sedative strategy.
Villa, F., Citerio, G. (2013). Sedation and Analgesia in Neurointensive Care. In A.J. Layon, A. Gabrielli, W.A. Friedman (a cura di), Textbook of neurointensive care - 2nd edition (pp. 281-291). Springer-Verlag [10.1007/978-1-4471-5226-2_14].
Sedation and Analgesia in Neurointensive Care
Citerio, G
2013
Abstract
In the neurointensive care setting, specific considerations of sedation are required; sedation may act as a therapeutic agent itself, when causing a reduction in cerebral metabolic rate of oxygen, cerebral blood flow, and intracranial pressure and in the incidence of seizures. However, the physician must be aware of the effects of every sedative agent on cerebral physiology, in order to obtain beneficial effects and avoid side effects. In this chapter, the effects of sedative agents on cerebral physiology are described in order to provide knowledge for an adequate sedative strategy.
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