Baroreflex sensitivity (BRS) is commonly assessed from spontaneous fluctuations of heart period (HP) and systolic arterial pressure (SAP) during general anesthesia. Unfortunately, general anesthesia depresses autonomic function and, consequently, spontaneous SAP variations could not be capable to drive HP changes, thus preventing the use of spontaneous variability to infer BRS. We applied two Granger causality approaches (F-test and Wald test) during two anesthesiological strategies (i.e. sevoflurane plus remifentanil or propofol plus remifentanil). We found a significant Granger-causality from SAP to HP independently of the anesthesiological strategy; thus suggesting that techniques estimating BRS from spontaneous variability can be utilized during general anesthesia. © 2011 Elsevier Ltd.

Bassani, T., Magagnin, V., Guzzetti, S., Baselli, G., Citerio, G., Porta, A. (2012). Testing the involvement of baroreflex during general anesthesia through Granger causality approach. COMPUTERS IN BIOLOGY AND MEDICINE, 42(3), 306-312 [10.1016/j.compbiomed.2011.03.005].

Testing the involvement of baroreflex during general anesthesia through Granger causality approach

CITERIO, GIUSEPPE
Penultimo
;
2012

Abstract

Baroreflex sensitivity (BRS) is commonly assessed from spontaneous fluctuations of heart period (HP) and systolic arterial pressure (SAP) during general anesthesia. Unfortunately, general anesthesia depresses autonomic function and, consequently, spontaneous SAP variations could not be capable to drive HP changes, thus preventing the use of spontaneous variability to infer BRS. We applied two Granger causality approaches (F-test and Wald test) during two anesthesiological strategies (i.e. sevoflurane plus remifentanil or propofol plus remifentanil). We found a significant Granger-causality from SAP to HP independently of the anesthesiological strategy; thus suggesting that techniques estimating BRS from spontaneous variability can be utilized during general anesthesia. © 2011 Elsevier Ltd.
Articolo in rivista - Articolo scientifico
Autonomic nervous system; Baroreflex; Cardiovascular control; General anesthesia; Granger causality; Adolescent; Adult; Aged; Anesthesia, General; Anesthetics; Baroreflex; Blood Pressure; Computer Simulation; Craniotomy; Electrocardiography; Humans; Methyl Ethers; Middle Aged; Piperidines; Propofol; Regression Analysis; Signal Processing, Computer-Assisted; Statistics, Nonparametric; Models, Cardiovascular; Models, Statistical; Computer Science Applications1707 Computer Vision and Pattern Recognition; Health Informatics
English
2012
42
3
306
312
reserved
Bassani, T., Magagnin, V., Guzzetti, S., Baselli, G., Citerio, G., Porta, A. (2012). Testing the involvement of baroreflex during general anesthesia through Granger causality approach. COMPUTERS IN BIOLOGY AND MEDICINE, 42(3), 306-312 [10.1016/j.compbiomed.2011.03.005].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/54751
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