Epithelial ovarian cancer (EOC) is one of the most lethal gynecologic diseases, with survival rate virtually unchanged for the past 30 years. EOC comprises different histotypes with molecular and clinical heterogeneity, but up till now the present gold standard platinum-based treatment has been conducted without any patient stratification. The aim of the present study is to generate microRNA (miRNA) profiles characteristic of each stage I EOC histotype, to identify subtype-specific biomarkers to improve our understanding underlying the tumor mechanisms.

Calura, E., Fruscio, R., Paracchini, L., Bignotti, E., Ravaggi, A., Martini, P., et al. (2013). MiRNA landscape in stage I epithelial ovarian cancer defines the histotype specificities. CLINICAL CANCER RESEARCH, 19(15) [10.1158/1078-0432.CCR-13-0360].

MiRNA landscape in stage I epithelial ovarian cancer defines the histotype specificities

FRUSCIO, ROBERT;CEPPI, LORENZO;CATTORETTI, GIORGIO;MILANI, RODOLFO;MANGIONI, COSTANTINO;
2013

Abstract

Epithelial ovarian cancer (EOC) is one of the most lethal gynecologic diseases, with survival rate virtually unchanged for the past 30 years. EOC comprises different histotypes with molecular and clinical heterogeneity, but up till now the present gold standard platinum-based treatment has been conducted without any patient stratification. The aim of the present study is to generate microRNA (miRNA) profiles characteristic of each stage I EOC histotype, to identify subtype-specific biomarkers to improve our understanding underlying the tumor mechanisms.
Articolo in rivista - Articolo scientifico
Gene Expression Regulation, Neoplastic; Gene Expression Profiling; Ovarian Neoplasms; MicroRNAs; Neoplasm Staging; Humans; Prognosis; Microarray Analysis; Tumor Markers, Biological; Female; Neoplasms, Glandular and Epithelial
English
Calura, E., Fruscio, R., Paracchini, L., Bignotti, E., Ravaggi, A., Martini, P., et al. (2013). MiRNA landscape in stage I epithelial ovarian cancer defines the histotype specificities. CLINICAL CANCER RESEARCH, 19(15) [10.1158/1078-0432.CCR-13-0360].
Calura, E; Fruscio, R; Paracchini, L; Bignotti, E; Ravaggi, A; Martini, P; Sales, G; Beltrame, L; Clivio, L; Ceppi, L; Di Marino, M; Fuso Nerini, I; Zanotti, L; Cavalieri, D; Cattoretti, G; Perego, P; Milani, R; Katsaros, D; Tognon, G; Sartori, E; Pecorelli, S; Mangioni, C; D'Incalci, M; Romualdi, C; Marchini, S
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/53294
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