The use of Graphics Processing Units (GPUs) has recently witnessed ever growing applications for different computational analyses in the field of Life Sciences. In this work we present a CUDA-powered computational tool, named coagSODA, that was purposely developed and applied for the analysis of a large model of the blood coagulation cascade defined as a system of ordinary differential equations, based on both mass-action kinetics and Hill functions. We discuss the biological results of the parameter sweep analyses of this model, and show that GPUs can boost the computational performances up to 177× speedup.

Bellini, M., Besozzi, D., Cazzaniga, P., Mauri, G., Nobile, M. (2014). Simulation and Analysis of the Blood Coagulation Cascade Accelerated on GPU. In Proceedings - 2014 22nd Euromicro International Conference on Parallel, Distributed, and Network-Based Processing, PDP 2014 (pp.590-593). IEEE Press [10.1109/PDP.2014.52].

Simulation and Analysis of the Blood Coagulation Cascade Accelerated on GPU

BESOZZI, DANIELA;MAURI, GIANCARLO;NOBILE, MARCO SALVATORE
2014

Abstract

The use of Graphics Processing Units (GPUs) has recently witnessed ever growing applications for different computational analyses in the field of Life Sciences. In this work we present a CUDA-powered computational tool, named coagSODA, that was purposely developed and applied for the analysis of a large model of the blood coagulation cascade defined as a system of ordinary differential equations, based on both mass-action kinetics and Hill functions. We discuss the biological results of the parameter sweep analyses of this model, and show that GPUs can boost the computational performances up to 177× speedup.
slide + paper
GPU Computing, blood coagulation, parameter sweep
English
Euromicro International Conference on Parallel, Distributed, and Network-Based Processing
2014
Proceedings - 2014 22nd Euromicro International Conference on Parallel, Distributed, and Network-Based Processing, PDP 2014
978-1-4799-2729-6
2014
590
593
6787335
none
Bellini, M., Besozzi, D., Cazzaniga, P., Mauri, G., Nobile, M. (2014). Simulation and Analysis of the Blood Coagulation Cascade Accelerated on GPU. In Proceedings - 2014 22nd Euromicro International Conference on Parallel, Distributed, and Network-Based Processing, PDP 2014 (pp.590-593). IEEE Press [10.1109/PDP.2014.52].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/52221
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