IRIS – Institutional Research Information System
IRIS è il sistema di gestione della ricerca dell’Università degli Studi di Milano-Bicocca.Il repository BOA è il modulo del sistema dedicato alla raccolta e alla disseminazione della produzione scientifica di Ateneo. Le pubblicazioni sono ricercabili per parola chiave attraverso il box nella barra orizzontale in alto oppure, mediante il pulsante Sfoglia, per "Afferenza", "Autore", "Titolo", "Tipologia" o "Settore scientifico-disciplinare".
IRIS contiene inoltre alcuni moduli dedicati alla registrazione dei progetti e dei contratti, e alla reportistica avanzata per le attività di valutazione della ricerca
EnglishObjectives: To compare the diagnostic accuracy of dynamic contrast-enhanced (DCE) and diffusion-weighted (DW) MR imaging in detecting deep myometrial invasion in endometrial cancer, using surgical-pathological staging as reference standard. Methods: After searching a wide range of electronic databases and screening titles/abstracts, we obtained full papers for potentially eligible studies and evaluated according to predefined inclusion criteria. Quality assessmentwas conducted by adapting the Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2) checklist. From each study, we extracted information on diagnostic performance of DW and DCE sequences. After exploring heterogeneity, we adopted a bivariate generalized linear mixedmodel to compare the effect of the two MR sequences jointly on sensitivity and specificity. Results: Nine studies (442 patients) were considered. Significant evidence of heterogeneity was found only for specificity, both in DW and DCE imaging (I 2 = 70.8% and 70.6%). Pooled sensitivity of DW and DCE was 0.86 and specificity did not significantly differ (p=0.16) between the two sequences (DW=0.86 and DCE=0.82). No difference was found between 3-T and 1.5-T MR. There was no evidence of publication bias. Conclusions: MR diagnostic accuracy in presurgical detection of deep myometrial infiltration in endometrial cancer is high. DCE and DW imaging do not differ in sensitivity and specificity. Key Points: • Myometrial invasion is the most important morphological prognostic feature of endometrial cancer • MR diagnostic accuracy in presurgical detection of deep myometrial infiltration is high • MR examination including T2 and DCE imaging is considered the reference standard • DWimaging has been increasingly employed with heterogeneous results • This meta-analysis shows that DCE and DW do not differ in diagnostic accuracy. © European Society of Radiology 2014.
Andreano, A., Rechichi, G., Rebora, P., Sironi, S., Valsecchi, M.G., & Galimberti, S. (2014). MR diffusion imaging for preoperative staging of myometrial invasion in patients with endometrial cancer: a systematic review and meta-analysis. EUROPEAN RADIOLOGY, 24(6), 1327-1338 [10.1007/s00330-014-3139-4].
| Citazione: | Andreano, A., Rechichi, G., Rebora, P., Sironi, S., Valsecchi, M.G., & Galimberti, S. (2014). MR diffusion imaging for preoperative staging of myometrial invasion in patients with endometrial cancer: a systematic review and meta-analysis. EUROPEAN RADIOLOGY, 24(6), 1327-1338 [10.1007/s00330-014-3139-4]. | |
| Tipo: | Articolo in rivista - Articolo scientifico | |
| Carattere della pubblicazione: | Scientifica | |
| Presenza di un coautore afferente ad Istituzioni straniere: | No | |
| Titolo: | MR diffusion imaging for preoperative staging of myometrial invasion in patients with endometrial cancer: a systematic review and meta-analysis | |
| Autori: | Andreano, A; Rechichi, G; Rebora, P; Sironi, S; Valsecchi, MG; Galimberti, S | |
| Autori: | ||
| Data di pubblicazione: | 2014 | |
| Lingua: | English | |
| Rivista: | EUROPEAN RADIOLOGY | |
| Digital Object Identifier (DOI): | http://dx.doi.org/10.1007/s00330-014-3139-4 | |
| Appare nelle tipologie: | 01 - Articolo su rivista |
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